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Year 1995, Volume: 8 Issue: 1, 11 - 14, 01.01.1995

Abstract

References

  • Kayaalp O. Rasyonel Tedavi Yönünden Tıbbi Farmakoloji. Vol 2, 5th ed. Ankara: Faryal Mat-San ve Ud. Şti, 1991: 1109-1115.

Effects of diltiazem on renal function

Year 1995, Volume: 8 Issue: 1, 11 - 14, 01.01.1995

Abstract

We planned to investigate the effect of diltiazem on

urine volume, urine sodium (Na+) and potassium (K+) excretion and glomerular filtration rate (GFR). Twenty healthy men, aged between 23 and 36 (mean age: 29 ± 0.87) were examined. A double - blind placebo controlled study was completed by weekly intervals in 3 periods. In each period, first day no drug was given, the second day placebo, the third day diltiazem (30 mg or 60 mg) or placebo was given.

In the first 6 hour period following diltiazem 30 or 60 mg administration, increases in GFR (p<0.05), urine volume (p<0.01) and urine Na+ excretion were

significant (p<0.001), but increase in urine K+ excretion was not significant (p>0.05). In the next 18 hour period, we observed that diltiazem did not affect

the excretion of K+ urine volume and GFR (p> 0.05), but increased the excretion of Na+ (p<0.05).

References

  • Kayaalp O. Rasyonel Tedavi Yönünden Tıbbi Farmakoloji. Vol 2, 5th ed. Ankara: Faryal Mat-San ve Ud. Şti, 1991: 1109-1115.
There are 1 citations in total.

Details

Subjects Clinical Sciences
Journal Section Review Makaleler
Authors

S. Topçu This is me

S. Sağır This is me

F. Candan This is me

S. İçağasıoğlu This is me

C. Yıldırır This is me

Publication Date January 1, 1995
Published in Issue Year 1995 Volume: 8 Issue: 1

Cite

APA Topçu, S., Sağır, S., Candan, F., İçağasıoğlu, S., et al. (1995). Effects of diltiazem on renal function. Marmara Medical Journal, 8(1), 11-14.
AMA Topçu S, Sağır S, Candan F, İçağasıoğlu S, Yıldırır C. Effects of diltiazem on renal function. Marmara Med J. January 1995;8(1):11-14.
Chicago Topçu, S., S. Sağır, F. Candan, S. İçağasıoğlu, and C. Yıldırır. “Effects of Diltiazem on Renal Function”. Marmara Medical Journal 8, no. 1 (January 1995): 11-14.
EndNote Topçu S, Sağır S, Candan F, İçağasıoğlu S, Yıldırır C (January 1, 1995) Effects of diltiazem on renal function. Marmara Medical Journal 8 1 11–14.
IEEE S. Topçu, S. Sağır, F. Candan, S. İçağasıoğlu, and C. Yıldırır, “Effects of diltiazem on renal function”, Marmara Med J, vol. 8, no. 1, pp. 11–14, 1995.
ISNAD Topçu, S. et al. “Effects of Diltiazem on Renal Function”. Marmara Medical Journal 8/1 (January 1995), 11-14.
JAMA Topçu S, Sağır S, Candan F, İçağasıoğlu S, Yıldırır C. Effects of diltiazem on renal function. Marmara Med J. 1995;8:11–14.
MLA Topçu, S. et al. “Effects of Diltiazem on Renal Function”. Marmara Medical Journal, vol. 8, no. 1, 1995, pp. 11-14.
Vancouver Topçu S, Sağır S, Candan F, İçağasıoğlu S, Yıldırır C. Effects of diltiazem on renal function. Marmara Med J. 1995;8(1):11-4.