Twenty patients with palpable cervical lymphadenopathy underwent Tc-99m (V) DMSA scintigraphy during their diagnostic work-up. In this prospective study, the scintigraphic findings were correlated with the clinical diagnoses and the results of the routine laboratory tests (complete blood count, biochemical analyses, chest X-ray, and tuberculin skin tests) and histopathological examinations of the excisional biopsy specimens.
In patients with tuberculous lymphadenitis (diagnosed clinically and histopathologically) the intense Tc-99m (V) DMSA uptake in the involved cervical lymph nodes was found to be significant.
In seems thaï Tc-99m (V) DMSA scintigraphy is a safe and non-invasive diagnostic imaging modality, that may be utilized in the initial work-up to assist in the differential diagnosis of cervical
lymphadenopathies. The observed affinity of the radiopharmaceutical for mycobacteria-infected cervical lymph nodes seems to be congruent with the localization mechanism (i.e. structural similarity to phosphate ion) proposed by Ohta and his coworkers.
Cervical lymphadenopathy tuberculous lymphadenitis mycobacterial lymphadenitis Tc-99m (V) DMSA scintigraphy
Subjects | Clinical Sciences |
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Journal Section | Review Makaleler |
Authors | |
Publication Date | March 1, 1995 |
Published in Issue | Year 1995 Volume: 8 Issue: 2 |