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Comparsion of "2-octyl-cyanoacrylate" and suture in the closure of skin graft

Year 1998, Volume: 11 Issue: 2, 83 - 90, 01.03.1998

Abstract

Objective: Every year emergency clinics are accepting many patients having traumatic injuries. Suturing the lacerated injury using local anesthetics and injection materials creates stress and fear in patients; besides suturing is a time taking procedure. The cyanoacyrylate derivatives that have been first used as tissue glues in 1950 have improved quite a lot up to date. At present they are being used in various areas of otolaryngology-head and neck surgery.

Methods: In this study a total of 8 adult Wistar albino rats have been used; 6 of them being the study group and 2 of them being the control group. On the back of 2 rats pediculated and rectangle shaped (2x4 cm in size) skin flaps; on the back of another 2 rats triangle shaped skin flaps and finally on the remaining 2 rats rectangle shaped skin flaps with irregular edges (traumatic) were elevated. Then Coaptex® (2-octyl- cyanoacrylate) tissue glue has been applied underneath the flaps and flaps were glued back to their original places. In the control group (2 rats) pediculated rectangle shaped (2x4 cm) skin flaps were elevated and have been stitched back to their places using 4/0 silk thread.

Results: In the study group very good clinical and cosmetic healing was observed, in the control group mild edema was detected first, then at later stages this edema slowly disappeared. No other problem worth mentioning was detected, fn the histopathological evaluation subcutaneous moderate foreign body reaction was detected in the study group

(Coaptex group), however epidermis had healed completely. In the control group, however, severe acute inflammation was detected in all layers of incision, epidermis had disappeared with superficial ulceration taking its place and no regeneration being present underneath.

Conclusion: We believe tissue glues can be used with confidence in the treatment of lacerations because they give cosmetically and histopathologically very good results. They can be applied easily and quickly, they give no pain to the patient and they do not require local anesthesia.

References

  • Trott AT. Cyanoacrylate tissue adhesives (An Advance in wound care). JAPTA 1997;277:1559- 1560.
Year 1998, Volume: 11 Issue: 2, 83 - 90, 01.03.1998

Abstract

References

  • Trott AT. Cyanoacrylate tissue adhesives (An Advance in wound care). JAPTA 1997;277:1559- 1560.
There are 1 citations in total.

Details

Subjects Clinical Sciences
Journal Section Review Makaleler
Authors

T. Şapçı This is me

A. Karavuş This is me

G. Yıldırım This is me

H. Onmuş This is me

M. Gürdal This is me

İ. Kurtuluş This is me

Publication Date March 1, 1998
Published in Issue Year 1998 Volume: 11 Issue: 2

Cite

APA Şapçı, T., Karavuş, A., Yıldırım, G., Onmuş, H., et al. (1998). Comparsion of "2-octyl-cyanoacrylate" and suture in the closure of skin graft. Marmara Medical Journal, 11(2), 83-90.
AMA Şapçı T, Karavuş A, Yıldırım G, Onmuş H, Gürdal M, Kurtuluş İ. Comparsion of "2-octyl-cyanoacrylate" and suture in the closure of skin graft. Marmara Med J. March 1998;11(2):83-90.
Chicago Şapçı, T., A. Karavuş, G. Yıldırım, H. Onmuş, M. Gürdal, and İ. Kurtuluş. “Comparsion of ‘2-Octyl-Cyanoacrylate’ and Suture in the Closure of Skin Graft”. Marmara Medical Journal 11, no. 2 (March 1998): 83-90.
EndNote Şapçı T, Karavuş A, Yıldırım G, Onmuş H, Gürdal M, Kurtuluş İ (March 1, 1998) Comparsion of "2-octyl-cyanoacrylate" and suture in the closure of skin graft. Marmara Medical Journal 11 2 83–90.
IEEE T. Şapçı, A. Karavuş, G. Yıldırım, H. Onmuş, M. Gürdal, and İ. Kurtuluş, “Comparsion of ‘2-octyl-cyanoacrylate’ and suture in the closure of skin graft”, Marmara Med J, vol. 11, no. 2, pp. 83–90, 1998.
ISNAD Şapçı, T. et al. “Comparsion of ‘2-Octyl-Cyanoacrylate’ and Suture in the Closure of Skin Graft”. Marmara Medical Journal 11/2 (March 1998), 83-90.
JAMA Şapçı T, Karavuş A, Yıldırım G, Onmuş H, Gürdal M, Kurtuluş İ. Comparsion of "2-octyl-cyanoacrylate" and suture in the closure of skin graft. Marmara Med J. 1998;11:83–90.
MLA Şapçı, T. et al. “Comparsion of ‘2-Octyl-Cyanoacrylate’ and Suture in the Closure of Skin Graft”. Marmara Medical Journal, vol. 11, no. 2, 1998, pp. 83-90.
Vancouver Şapçı T, Karavuş A, Yıldırım G, Onmuş H, Gürdal M, Kurtuluş İ. Comparsion of "2-octyl-cyanoacrylate" and suture in the closure of skin graft. Marmara Med J. 1998;11(2):83-90.