IMPRESSION CYTOLOGY (IC) IN CLINICAL PRACTICE

Year 2000, Volume: 13 Issue: 2, 75 - 81, 03.12.2016

Tarık Şapçı Ahmet Karavuş Hale Onmuş Melda Karavuş Uğur Günter Akbulut

Abstract

Objective: Nasal cytology is the most useful technique in differentiating infectious rhinitis from other types of rhinitis. Various techniques have been described for obtaining nasal cytology specimens, including blowing secretions into wax paper; taking a smear by using cotton wool swabs or brushes; or performing nasal scraping, lavage, biopsy and impression cytology.
We aimed to compare impression cytology findings between allergic, vasomotor and infectious rhinitis patients and the control group as far as eosinophils, neutrophils, basophilic cell, goblet cells and bacteria counts were concerned.
Material and Method: In this study, we used an alternative method, namely Impression Cytology (1C) which is a noninvasive diagnostic procedure allowing the collection of a monolayer of cells from the epithelial or mucous surface. 1C was used in 28 allergic rhinitis, 21 vasomotor rhinitis and 23 infectious rhinitis patients. There were 22 control subjects in this study.
Results: IC was found to show significantly higher gradings of eosinophil counts and goblet cell counts in allergic rhinitis patients as
compared to other groups (p<0.001); whereas neutrophil counts were found to be higher in the infectious rhinitis patients as compared to other groups (p<0.001). In the basophilic cell counts allergic rhinitis and the infectious rhinitis patients were found to present higher gradings as compared to the control group (p<0.05). Bacteria invasion detected by IC was present only in the infectious rhinitis patients with a percentage of
26.1.
Conclusion: Our study has shown that IC is a very valuable and practical technique, offering a valuable alternative test for investigating cytology in all rhinitis and other pathologies causing cytologic changes.
Key Words: Impression cytology, rhinitis,
eosinophil, basophilic cell, neutrophil.

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