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INTRATUNICAL INSTILLATION OF BUPIVACAINE AND METHYLPREDNISOLONE FOR RELIEF OF SCROTAL PAIN AND SWELLING FROM TESE OR MESA

Year 2001, Volume: 14 Issue: 1, 12 - 15, 03.12.2016

Abstract

Objective: Scrotal pain and swelling due to surgical sperm retrieval procedures and peritesticular fibrosis, as a problem of late term, create significant morbidity in the postoperative life of patients and affect possible future sperm retrieval procedures.
Methods: Thirty-one patients received NSAIDS postoperatively by IM (intramuscular) route without local anaesthetic agent and/or corticosteroid instillation around the testicles before closure of the tunica vaginalis-control group-. No NSAIDS were given to the remaining 34 patients in whom 2.5 ml of 0.5% bupivacaine combined with 10 mg/ml. methylprednisolone were introduced before closing of the tunica vaginalis. The mean pain scale scores and duration of painless period after surgery between the two groups were evaluated.
Results: The mean pain score difference was not statistically significant just after surgery between the two groups (p>0.05), while the differences were significant for 2 and 4 hours after surgery (p<0.05 and p<0.01). The mean duration of pain free interval (hours) after the procedure was 47.8 ± 16.9 (12-72) hours in the intratunical instillated group patients, and 10
(29%) and 23 (67%) of them were completely free of pain and had no scrotal swelling, respectively. Meanwhile, in the control group, the mean painless period was 9.9 ± 3.6 (4-20) hours, after second NSAID, and 30 of them (97%) had scrotal swelling, postoperatively.
Conclusion: This study confirms that direct intratunical Instillation of bupivacaine and methylprednisolone around the testis reduces postoperative pain, scrotal swelling and peritesticular fibrosis. Controlling of post surgical scrotal pain and edema results in more rapid return to daily activities and work.
Key Words: ICSI, Pain, Scrotum, Surgical sperm retrieval, Testis

References

  • Krarup T. Essential testodynia. Ugeskr Laeger 1998; 160: 7444-7446.
  • Ezeh Ul, Shepherd S, Moore HD, Cooke ID. Morbidity and cost-effectiveness analysis of outpatient analgesia versus general anaesthesia for testicular sperm extraction in men with azoospermia due to defects in spermatogenesis. Hum Repro 1999; 14: 321- 328.
  • Pfeiffer U, McLoughlin GA, Dodson ME. Wound instillation for postoperative pain relief. Br J Surg 1989; 76: 315.
  • Spittal MJ, Hunter SJ. A comparison of bupivacaine instillation and inguinal field block for control of pain after herniorrhaphy. Ann R Coll Surg Engl 1992; 74: 85-88.
  • Weber A, Munoz J, Garteiz D, Cueto J. Use of subdiaphragmatic bupivacaine instillation to control postoperative pain after laparoscopic surgery. Surg Laparosc Endosc 1997; 7: 6-8.
  • Wong C, Rees Bl. Randomized trial of periportal peritoneal bupivacaine for pain relief after laparoscopic cholecystectomy. Br J Surg 1997; 84: 138.
  • Saunders PRi, Hendry WE. Bupivacaine instillation for the relief of pain from testicular biopsy. Br J Urol 1998; 82: 911.
  • Beck DE, Opelka EG. Perioperative steroid use in colorectal patients: results of a survey. Dis Colon Rectum 1996; 39: 995-999.
  • Esen E, Tasar E, Akhan OJ. Determination of the anti-inflammatory effects of méthylprednisolone on the sequelae of third molar surgery. Oral Maxillofas Surg 1999; 57: 1201-1206.
  • Citardi MJ, Kuhn EA. Endoscopically guided frontal sinus beciomethasone instillation for refractory frontal sinus/recess mucosal edema and polyposis. Am J RhinoI 1998; 12: 179-182.
  • Assîmes TL, Lessard ML. The use of perioperative corticosteroids in cranio maxillofascial surgery. Plast Reconstr Surg 1999; 103: 313-321.
  • Watanuki C, Doi I, Watanuki A, Sakai H, Sumiya A, Ota Y. Effect of steroids on postoperative pain and pyrexia. Masui 1991; 40: 570-573.
Year 2001, Volume: 14 Issue: 1, 12 - 15, 03.12.2016

Abstract

References

  • Krarup T. Essential testodynia. Ugeskr Laeger 1998; 160: 7444-7446.
  • Ezeh Ul, Shepherd S, Moore HD, Cooke ID. Morbidity and cost-effectiveness analysis of outpatient analgesia versus general anaesthesia for testicular sperm extraction in men with azoospermia due to defects in spermatogenesis. Hum Repro 1999; 14: 321- 328.
  • Pfeiffer U, McLoughlin GA, Dodson ME. Wound instillation for postoperative pain relief. Br J Surg 1989; 76: 315.
  • Spittal MJ, Hunter SJ. A comparison of bupivacaine instillation and inguinal field block for control of pain after herniorrhaphy. Ann R Coll Surg Engl 1992; 74: 85-88.
  • Weber A, Munoz J, Garteiz D, Cueto J. Use of subdiaphragmatic bupivacaine instillation to control postoperative pain after laparoscopic surgery. Surg Laparosc Endosc 1997; 7: 6-8.
  • Wong C, Rees Bl. Randomized trial of periportal peritoneal bupivacaine for pain relief after laparoscopic cholecystectomy. Br J Surg 1997; 84: 138.
  • Saunders PRi, Hendry WE. Bupivacaine instillation for the relief of pain from testicular biopsy. Br J Urol 1998; 82: 911.
  • Beck DE, Opelka EG. Perioperative steroid use in colorectal patients: results of a survey. Dis Colon Rectum 1996; 39: 995-999.
  • Esen E, Tasar E, Akhan OJ. Determination of the anti-inflammatory effects of méthylprednisolone on the sequelae of third molar surgery. Oral Maxillofas Surg 1999; 57: 1201-1206.
  • Citardi MJ, Kuhn EA. Endoscopically guided frontal sinus beciomethasone instillation for refractory frontal sinus/recess mucosal edema and polyposis. Am J RhinoI 1998; 12: 179-182.
  • Assîmes TL, Lessard ML. The use of perioperative corticosteroids in cranio maxillofascial surgery. Plast Reconstr Surg 1999; 103: 313-321.
  • Watanuki C, Doi I, Watanuki A, Sakai H, Sumiya A, Ota Y. Effect of steroids on postoperative pain and pyrexia. Masui 1991; 40: 570-573.
There are 12 citations in total.

Details

Journal Section Original Research
Authors

Tibet Erdogru This is me

Esra Akyol This is me

Süleyman Tosun This is me

Numan Bayazıt This is me

Publication Date December 3, 2016
Published in Issue Year 2001 Volume: 14 Issue: 1

Cite

APA Erdogru, T., Akyol, E., Tosun, S., Bayazıt, N. (2016). INTRATUNICAL INSTILLATION OF BUPIVACAINE AND METHYLPREDNISOLONE FOR RELIEF OF SCROTAL PAIN AND SWELLING FROM TESE OR MESA. Marmara Medical Journal, 14(1), 12-15.
AMA Erdogru T, Akyol E, Tosun S, Bayazıt N. INTRATUNICAL INSTILLATION OF BUPIVACAINE AND METHYLPREDNISOLONE FOR RELIEF OF SCROTAL PAIN AND SWELLING FROM TESE OR MESA. Marmara Med J. June 2016;14(1):12-15.
Chicago Erdogru, Tibet, Esra Akyol, Süleyman Tosun, and Numan Bayazıt. “INTRATUNICAL INSTILLATION OF BUPIVACAINE AND METHYLPREDNISOLONE FOR RELIEF OF SCROTAL PAIN AND SWELLING FROM TESE OR MESA”. Marmara Medical Journal 14, no. 1 (June 2016): 12-15.
EndNote Erdogru T, Akyol E, Tosun S, Bayazıt N (June 1, 2016) INTRATUNICAL INSTILLATION OF BUPIVACAINE AND METHYLPREDNISOLONE FOR RELIEF OF SCROTAL PAIN AND SWELLING FROM TESE OR MESA. Marmara Medical Journal 14 1 12–15.
IEEE T. Erdogru, E. Akyol, S. Tosun, and N. Bayazıt, “INTRATUNICAL INSTILLATION OF BUPIVACAINE AND METHYLPREDNISOLONE FOR RELIEF OF SCROTAL PAIN AND SWELLING FROM TESE OR MESA”, Marmara Med J, vol. 14, no. 1, pp. 12–15, 2016.
ISNAD Erdogru, Tibet et al. “INTRATUNICAL INSTILLATION OF BUPIVACAINE AND METHYLPREDNISOLONE FOR RELIEF OF SCROTAL PAIN AND SWELLING FROM TESE OR MESA”. Marmara Medical Journal 14/1 (June 2016), 12-15.
JAMA Erdogru T, Akyol E, Tosun S, Bayazıt N. INTRATUNICAL INSTILLATION OF BUPIVACAINE AND METHYLPREDNISOLONE FOR RELIEF OF SCROTAL PAIN AND SWELLING FROM TESE OR MESA. Marmara Med J. 2016;14:12–15.
MLA Erdogru, Tibet et al. “INTRATUNICAL INSTILLATION OF BUPIVACAINE AND METHYLPREDNISOLONE FOR RELIEF OF SCROTAL PAIN AND SWELLING FROM TESE OR MESA”. Marmara Medical Journal, vol. 14, no. 1, 2016, pp. 12-15.
Vancouver Erdogru T, Akyol E, Tosun S, Bayazıt N. INTRATUNICAL INSTILLATION OF BUPIVACAINE AND METHYLPREDNISOLONE FOR RELIEF OF SCROTAL PAIN AND SWELLING FROM TESE OR MESA. Marmara Med J. 2016;14(1):12-5.