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THE ROLE OF CYSTOSCOPY IN THE EVALUATION OF HEMATURIA IN THE PRESENCE OF NORMAL RADIOLOGICAL AND MICROBIOLOGICAL WORK-UP

Year 2003, Volume: 16 Issue: 4, 255 - 260, 03.12.2016

Abstract

Objective: The etiology of microscopic and
macroscopic hematuria may range from
conditions posing minimal risk to the patient to
potentially life-threatening conditions. There are
contraversial ideas about the evaluation of
hematuria. In this survey, we examined the
necessity of cystoscopy in patients with
microscopic and macroscopic hematuria who
were radiologically and microbiologically normal.
Methods: A total of 139 patients with
microscopic or macroscopic hematuria who were
microbiologically and radiologically normal and
had cystoscopy between 1991 and 2003 were
retrospectively analyzed. Routine history,
physical examination, routine blood tests, urine
analysis, urine culture, a plain radiography,
urinary system ultrasonography / intravenous
pyelography, computerized tomography and
tuberculosis tests, including ARB-Bactec were
unable to diagnose a pathology to identify the
reason for hematuria, and cystoscopy was
performed on all patients.
R e su lts : Seventy five (53.9%) patients were
male and 64 (46.1%) were female. There was
no pathology in 86 (61.8%) patients in
diagnostic cystoscopy whereas, 21(15.2%) had
a papillary tumor and 16 (11.5%) had a
suspicious lesion in the bladder that was
biopsied. In 16 (11.5%) patients prostatic
hypertrophy was the only cystoscopic finding.
According to the histopathological examination,
15 (93.5%) of the suspicious lesion biopsies
were benign, but 1 (6.5%) patient had
carcinoma in-situ. All of the papillary lesions
were reported as superficial transitional cell
carcinoma (TCCA). Overall, TCCA was detected
in 4(4.9%) and 18(31%) patients with
microscopic and macroscopic hematuria,
respectively. Irrespective of the type of the
hematuria, none of the patients under 40 years
of age were found to have bladder cancer.
C o n c lu s io n : Our findings indicate that all
patients older than 40 years of age with
microscopic and macroscopic hematuria should
undergo a cystoscopy. The current study further
suggests that patients younger than 40 years of
age with microscopic hematuria can only be
safely followed up with non-invasive methods,
without performing cystoscopy.
K e y W o rd s : Microscopic, Macroscopic,
Hematuria, Cystoscopy, Diagnosis

References

  • Khan MA, Shaw G, Paris AMI. Is microscopic hematuria an urological emergency? BJU Int 2002; 90; 355-357.
  • Benson G, Brewer E. Hematuria algorithms for diagnosis hematuria in the adult and hematuria secondary to trauma. JAMA 1981; 246; 993-995.
  • Suzuki Y, Sasagawa I, Abe Y, et al. Indication of cystoscopy in patients with asymptomatic microscopic hematuria. Scand J Urol Hep tiro I 2000; 34; 51-54.
  • Messing EM, Young TB, Hunt VE, et al. Home
  • screening for hematuria: results of a
  • multiclinic study. J Urol 1992; 148; 289-292.
  • Messing EM, Young TB, Hunt VE, et al. Hematuria home screenig: repeat testing results. J Urol 1995; 154; 57.
  • Cowin H, Silverstein M. The diagnosis of neoplasia in patients with asymptomatic microscopic hematuria: a decision analysis. J Urol 1988; 139; 1002-1006.
  • Lowe PC, Brendler CB. Evaluation of the urologie patient. In: Walsh PC et a! eds: Campbell's Urology, 6. ed. Vol. I. Philadelphia: Saunders, 1992;, 307-331.
  • Proom P, Ribak J, Benbassat J. Significance of microhematuria in young adults. Br Med J 1984; 288; 20-22.
  • Mariani AJ, Mariani MC, Macchioni C, et al. The significance of adult hematuria: 1000 hematuria evaluation including a risk-benefit and cost-effectiveness analysis. J Urol 1989; 141; 350-355.
  • Golin AL, Howard RS. Asymptomatic microscopic hematuria. J Urol 1980; 124; 389-391.
  • Sutton JM. Evaluation of hematuria in adults. JAMA; 1990; 263; 2475.
  • Khadra MH, Pickard RS, Charlton M, et al. A prospective analysis of 1930 patients with
  • hematuria to evaluate current diagnostic practice. J Urol 2000; 163; 524-527.
  • Britton JP, Dowell AC, Whelan P, et al. A community study of bladder cancer screening by the detection of occulturinary bleeding. J Urol 1992: 148; 788-790.
  • Mohr DH. Offord KP, Owen RA et al. Asymptomatic microhematuria and urologie disease: a population based study. JAMA 1986; 256; 224-229.
  • Schôder PH. Microscopic hematuria. Br Med J 1994; 309; 70-72.
  • Mayfield MP, Whelan P. Bladder tumors detected on screening: results at 7 years. Br J Urol 1998; 82; 825-828.
  • 7. Thompson IM. The evaluation of microscopic hematuria:a population based study. J Urol 1987; 138: 1189-1 190.
  • Murakami S, Igarashi T, Hara S. et al. Strategies for asymptomatic microscopic hematuria: a prospective study of 1034 patients. J Urol 1990; 144; 99-101.
  • Kupor LR, Mullins JD, McPhaul JJ. Immunopathologie findings in idiopathic renal hematuria. Arch Intern Pled 1975; 135; 1204- 1211.
  • Topham PS, Harper SJ, Furness PH, et al. Glomerular disease as a cause of isolated microscopic hematuria. Quart J Med 1994; 87; 329-335.
  • Grossfeld G, Litwin PI, Wolf S. Evaluation of asymptomatic microscopic hematuria in adults: the American Urological Association best practice policy-Part 11: Patient evaluation, cytology, voided markers, imaging, cystoscopy, nephrology evaluation and followup. J Urol 2001; 57; 604-610.
  • Carson CC, Segura JW, Greene LP. Clinical importance of microhematuria. JAMA 1979; 241; 149-150.
  • Howard R, Grolin A. Long term follow-up of asymptomatic m
Year 2003, Volume: 16 Issue: 4, 255 - 260, 03.12.2016

Abstract

References

  • Khan MA, Shaw G, Paris AMI. Is microscopic hematuria an urological emergency? BJU Int 2002; 90; 355-357.
  • Benson G, Brewer E. Hematuria algorithms for diagnosis hematuria in the adult and hematuria secondary to trauma. JAMA 1981; 246; 993-995.
  • Suzuki Y, Sasagawa I, Abe Y, et al. Indication of cystoscopy in patients with asymptomatic microscopic hematuria. Scand J Urol Hep tiro I 2000; 34; 51-54.
  • Messing EM, Young TB, Hunt VE, et al. Home
  • screening for hematuria: results of a
  • multiclinic study. J Urol 1992; 148; 289-292.
  • Messing EM, Young TB, Hunt VE, et al. Hematuria home screenig: repeat testing results. J Urol 1995; 154; 57.
  • Cowin H, Silverstein M. The diagnosis of neoplasia in patients with asymptomatic microscopic hematuria: a decision analysis. J Urol 1988; 139; 1002-1006.
  • Lowe PC, Brendler CB. Evaluation of the urologie patient. In: Walsh PC et a! eds: Campbell's Urology, 6. ed. Vol. I. Philadelphia: Saunders, 1992;, 307-331.
  • Proom P, Ribak J, Benbassat J. Significance of microhematuria in young adults. Br Med J 1984; 288; 20-22.
  • Mariani AJ, Mariani MC, Macchioni C, et al. The significance of adult hematuria: 1000 hematuria evaluation including a risk-benefit and cost-effectiveness analysis. J Urol 1989; 141; 350-355.
  • Golin AL, Howard RS. Asymptomatic microscopic hematuria. J Urol 1980; 124; 389-391.
  • Sutton JM. Evaluation of hematuria in adults. JAMA; 1990; 263; 2475.
  • Khadra MH, Pickard RS, Charlton M, et al. A prospective analysis of 1930 patients with
  • hematuria to evaluate current diagnostic practice. J Urol 2000; 163; 524-527.
  • Britton JP, Dowell AC, Whelan P, et al. A community study of bladder cancer screening by the detection of occulturinary bleeding. J Urol 1992: 148; 788-790.
  • Mohr DH. Offord KP, Owen RA et al. Asymptomatic microhematuria and urologie disease: a population based study. JAMA 1986; 256; 224-229.
  • Schôder PH. Microscopic hematuria. Br Med J 1994; 309; 70-72.
  • Mayfield MP, Whelan P. Bladder tumors detected on screening: results at 7 years. Br J Urol 1998; 82; 825-828.
  • 7. Thompson IM. The evaluation of microscopic hematuria:a population based study. J Urol 1987; 138: 1189-1 190.
  • Murakami S, Igarashi T, Hara S. et al. Strategies for asymptomatic microscopic hematuria: a prospective study of 1034 patients. J Urol 1990; 144; 99-101.
  • Kupor LR, Mullins JD, McPhaul JJ. Immunopathologie findings in idiopathic renal hematuria. Arch Intern Pled 1975; 135; 1204- 1211.
  • Topham PS, Harper SJ, Furness PH, et al. Glomerular disease as a cause of isolated microscopic hematuria. Quart J Med 1994; 87; 329-335.
  • Grossfeld G, Litwin PI, Wolf S. Evaluation of asymptomatic microscopic hematuria in adults: the American Urological Association best practice policy-Part 11: Patient evaluation, cytology, voided markers, imaging, cystoscopy, nephrology evaluation and followup. J Urol 2001; 57; 604-610.
  • Carson CC, Segura JW, Greene LP. Clinical importance of microhematuria. JAMA 1979; 241; 149-150.
  • Howard R, Grolin A. Long term follow-up of asymptomatic m
There are 26 citations in total.

Details

Journal Section Original Research
Authors

Cenk Yazıcı This is me

Levent Türkeri This is me

Yalçın Ülker This is me

Ferruh Şimşek This is me

Publication Date December 3, 2016
Published in Issue Year 2003 Volume: 16 Issue: 4

Cite

APA Yazıcı, C., Türkeri, L., Ülker, Y., Şimşek, F. (2016). THE ROLE OF CYSTOSCOPY IN THE EVALUATION OF HEMATURIA IN THE PRESENCE OF NORMAL RADIOLOGICAL AND MICROBIOLOGICAL WORK-UP. Marmara Medical Journal, 16(4), 255-260.
AMA Yazıcı C, Türkeri L, Ülker Y, Şimşek F. THE ROLE OF CYSTOSCOPY IN THE EVALUATION OF HEMATURIA IN THE PRESENCE OF NORMAL RADIOLOGICAL AND MICROBIOLOGICAL WORK-UP. Marmara Med J. March 2016;16(4):255-260.
Chicago Yazıcı, Cenk, Levent Türkeri, Yalçın Ülker, and Ferruh Şimşek. “THE ROLE OF CYSTOSCOPY IN THE EVALUATION OF HEMATURIA IN THE PRESENCE OF NORMAL RADIOLOGICAL AND MICROBIOLOGICAL WORK-UP”. Marmara Medical Journal 16, no. 4 (March 2016): 255-60.
EndNote Yazıcı C, Türkeri L, Ülker Y, Şimşek F (March 1, 2016) THE ROLE OF CYSTOSCOPY IN THE EVALUATION OF HEMATURIA IN THE PRESENCE OF NORMAL RADIOLOGICAL AND MICROBIOLOGICAL WORK-UP. Marmara Medical Journal 16 4 255–260.
IEEE C. Yazıcı, L. Türkeri, Y. Ülker, and F. Şimşek, “THE ROLE OF CYSTOSCOPY IN THE EVALUATION OF HEMATURIA IN THE PRESENCE OF NORMAL RADIOLOGICAL AND MICROBIOLOGICAL WORK-UP”, Marmara Med J, vol. 16, no. 4, pp. 255–260, 2016.
ISNAD Yazıcı, Cenk et al. “THE ROLE OF CYSTOSCOPY IN THE EVALUATION OF HEMATURIA IN THE PRESENCE OF NORMAL RADIOLOGICAL AND MICROBIOLOGICAL WORK-UP”. Marmara Medical Journal 16/4 (March 2016), 255-260.
JAMA Yazıcı C, Türkeri L, Ülker Y, Şimşek F. THE ROLE OF CYSTOSCOPY IN THE EVALUATION OF HEMATURIA IN THE PRESENCE OF NORMAL RADIOLOGICAL AND MICROBIOLOGICAL WORK-UP. Marmara Med J. 2016;16:255–260.
MLA Yazıcı, Cenk et al. “THE ROLE OF CYSTOSCOPY IN THE EVALUATION OF HEMATURIA IN THE PRESENCE OF NORMAL RADIOLOGICAL AND MICROBIOLOGICAL WORK-UP”. Marmara Medical Journal, vol. 16, no. 4, 2016, pp. 255-60.
Vancouver Yazıcı C, Türkeri L, Ülker Y, Şimşek F. THE ROLE OF CYSTOSCOPY IN THE EVALUATION OF HEMATURIA IN THE PRESENCE OF NORMAL RADIOLOGICAL AND MICROBIOLOGICAL WORK-UP. Marmara Med J. 2016;16(4):255-60.