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A case of Krukenberg tumor, eight years after treatment of gastric cancer

Year 2018, Volume: 31 Issue: 2, 81 - 84, 05.06.2018
https://doi.org/10.5472/marumj.430802

Abstract

Krukenberg tumor is a rare metastatic tumor of the ovary. The
primary tumors are usually gastrointestinal cancers. Most of the
Krukenberg tumors reported in the literature occurred within the
first 2 years after treatment of the primary disease. Herein, we
present a case of Krukenberg tumor in a 37-year-old woman who
previously underwent surgery and chemotherapy for stomach
cancer. This patient is noteworthy because it is one of the few
documented cases of ovarian metastasis appearing after a diseasefree
period of 8 years following treatment of the primary tumor.
Krukenberg tumors are associated with poor prognosis; therefore,
regular gynecological examination in female patients with history
of gastric cancer is very important for the early diagnosis and
treatment of this disease.

References

  • Kubecek O, Laco J, Spacek J, et al. The pathogenesis, diagnosis, and management of metastatic tumors to the ovary: a comprehensive review. Clin Exp Metastasis 2017; 34 : 295- 307. doi: 10.1007/s10585-017-9856-8
  • Krukenberg F E. Fibrosarcoma ovarii mucocellulare (carcinomatodes). Arch Gynäkol 1896; 50: 287-321. doi: 10.1007/BF01700650
  • Schlagenhaufer F. Ueber das metastatische ovarial carcinom nach Krebs des Magens, Darmes, und anderer Bauchorgane. Monatschr Gebursth Gynakol 1902;1:485-528ç doi: 10.1159/000283419
  • Young RH. From Krukenberg to today: part I. Historical perspective, general principles, mucinous tumors including the Krukenberg tumor. Adv Anat Pathol 2006; 13: 205-7. doi: 10.1097/01.pap.0000213038.85704.e4
  • Malgorzata J, Janusz E. Krukenberg tumor—8 years after surgical treatment of gastric carcinoma. Ginekol Pol 2008; 79: 564-6.
  • Szarmach A, Swieton D, Szydlowska-Szarmach E, et al. Krukenberg tumor—a multidisciplinary approach—a case report. Ginekol Pol 2014; 85: 545-8.
  • Li W, Wang H, Wang J, Fangfang LV, Zhu X, Wang Z. Ovarian metastases resection from extragenital primary sites: outcome and prognostic factor analysis of 147 patients. BMC Cancer 2012; 12: 278. doi:10.1186/1471-2407-12-278
  • Aziz M, Kasi A. Cancer, Krukenberg Tumor. StatPearls [Internet].Treasure Island (FL): StatPearls Publishing; 2018. [Access on 14.03.2018]
  • Matsushita H, Watanabe K, Wakatsuki A. Metastatic gastric cancer to the female genital tract. Mol Clin Oncol 2016; 5: 495-9. doi: 10.3892/mco.2016.1035
  • Wu F, Zhao X, Mi B, et al. Clinical characteristics and prognostic analysis of Krukenberg tumor. Mol Clin Oncol 2015; 3: 1323-8. doi: 10.3892/mco.2015.634
  • Nakamura Y, Hiramatsu A, Koyama T, Oyama Y, Tanaka A, Honma K. A krukenberg tumor from an occult intramucosal gastric carcinoma identified during an autopsy. Case Rep Oncol Med 2014; 2014: 797429. doi: 10.1155/2014/797429
  • Kakushima N, Kamoshida T, Hirai S, et al. Early gastric cancer with Krukenberg tumor and review of cases of intramucosal gastric cancers with Krukenberg tumor. J Gastroenterol 2003; 38: 1176-80. doi:10.1007/s00535-003-1227-3
  • Yu P, Huang L, Cheng G, et al. Treatment strategy and prognostic factors for Krukenberg tumors of gastric origin: report of a 10-year single-center experience from China. Oncotarget 2017; 8: 82558-70. doi: 10.18632/ oncotarget.19759

Mide kanseri tedavisinden 8 yıl sonra gelişen Krukenberg tümörü olgusu

Year 2018, Volume: 31 Issue: 2, 81 - 84, 05.06.2018
https://doi.org/10.5472/marumj.430802

Abstract

Krukenberg tümörü overleri tutan, nadir görülen metastatik bir
tümördür. Sıklıkla primer odak gastrointestinal kanserlerdir.
Literatürdeki Krukenberg tümörlerinin çoğunluğu primer
hastalığın tedavisinden sonra ilk 2 yıl içinde meydana gelmektedir.
Biz burada mide kanseri nedeniyle cerrahi tedavi ve kemoterapi
uygulanmış 37 yaşında bir kadın hastada karşılaştığımız
Krukenberg olgusunu sunduk. Olgumuzun dikkat çeken tarafı
primer hastalığın tedavisinden sonra hastalıksız geçen 8 yılın
ardından over metastazı görülmesi olup, literatürdeki nadir
olgulardan biridir. Mide kanserli kadın hastalarda düzenli
jinekolojik muayene, prognozu oldukça kötü olan bu hastalığın
erken tanı ve tedavisi açısından önemlidir.

References

  • Kubecek O, Laco J, Spacek J, et al. The pathogenesis, diagnosis, and management of metastatic tumors to the ovary: a comprehensive review. Clin Exp Metastasis 2017; 34 : 295- 307. doi: 10.1007/s10585-017-9856-8
  • Krukenberg F E. Fibrosarcoma ovarii mucocellulare (carcinomatodes). Arch Gynäkol 1896; 50: 287-321. doi: 10.1007/BF01700650
  • Schlagenhaufer F. Ueber das metastatische ovarial carcinom nach Krebs des Magens, Darmes, und anderer Bauchorgane. Monatschr Gebursth Gynakol 1902;1:485-528ç doi: 10.1159/000283419
  • Young RH. From Krukenberg to today: part I. Historical perspective, general principles, mucinous tumors including the Krukenberg tumor. Adv Anat Pathol 2006; 13: 205-7. doi: 10.1097/01.pap.0000213038.85704.e4
  • Malgorzata J, Janusz E. Krukenberg tumor—8 years after surgical treatment of gastric carcinoma. Ginekol Pol 2008; 79: 564-6.
  • Szarmach A, Swieton D, Szydlowska-Szarmach E, et al. Krukenberg tumor—a multidisciplinary approach—a case report. Ginekol Pol 2014; 85: 545-8.
  • Li W, Wang H, Wang J, Fangfang LV, Zhu X, Wang Z. Ovarian metastases resection from extragenital primary sites: outcome and prognostic factor analysis of 147 patients. BMC Cancer 2012; 12: 278. doi:10.1186/1471-2407-12-278
  • Aziz M, Kasi A. Cancer, Krukenberg Tumor. StatPearls [Internet].Treasure Island (FL): StatPearls Publishing; 2018. [Access on 14.03.2018]
  • Matsushita H, Watanabe K, Wakatsuki A. Metastatic gastric cancer to the female genital tract. Mol Clin Oncol 2016; 5: 495-9. doi: 10.3892/mco.2016.1035
  • Wu F, Zhao X, Mi B, et al. Clinical characteristics and prognostic analysis of Krukenberg tumor. Mol Clin Oncol 2015; 3: 1323-8. doi: 10.3892/mco.2015.634
  • Nakamura Y, Hiramatsu A, Koyama T, Oyama Y, Tanaka A, Honma K. A krukenberg tumor from an occult intramucosal gastric carcinoma identified during an autopsy. Case Rep Oncol Med 2014; 2014: 797429. doi: 10.1155/2014/797429
  • Kakushima N, Kamoshida T, Hirai S, et al. Early gastric cancer with Krukenberg tumor and review of cases of intramucosal gastric cancers with Krukenberg tumor. J Gastroenterol 2003; 38: 1176-80. doi:10.1007/s00535-003-1227-3
  • Yu P, Huang L, Cheng G, et al. Treatment strategy and prognostic factors for Krukenberg tumors of gastric origin: report of a 10-year single-center experience from China. Oncotarget 2017; 8: 82558-70. doi: 10.18632/ oncotarget.19759
There are 13 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Case Reports
Authors

Servet Karagül This is me

Fatih Sümer This is me

Asım Onur This is me

Ali Tardu This is me

Adile Ferda Dağlı This is me

Cuneyt Kayaalp This is me

Publication Date June 5, 2018
Published in Issue Year 2018 Volume: 31 Issue: 2

Cite

APA Karagül, S., Sümer, F., Onur, A., Tardu, A., et al. (2018). A case of Krukenberg tumor, eight years after treatment of gastric cancer. Marmara Medical Journal, 31(2), 81-84. https://doi.org/10.5472/marumj.430802
AMA Karagül S, Sümer F, Onur A, Tardu A, Dağlı AF, Kayaalp C. A case of Krukenberg tumor, eight years after treatment of gastric cancer. Marmara Med J. May 2018;31(2):81-84. doi:10.5472/marumj.430802
Chicago Karagül, Servet, Fatih Sümer, Asım Onur, Ali Tardu, Adile Ferda Dağlı, and Cuneyt Kayaalp. “A Case of Krukenberg Tumor, Eight Years After Treatment of Gastric Cancer”. Marmara Medical Journal 31, no. 2 (May 2018): 81-84. https://doi.org/10.5472/marumj.430802.
EndNote Karagül S, Sümer F, Onur A, Tardu A, Dağlı AF, Kayaalp C (May 1, 2018) A case of Krukenberg tumor, eight years after treatment of gastric cancer. Marmara Medical Journal 31 2 81–84.
IEEE S. Karagül, F. Sümer, A. Onur, A. Tardu, A. F. Dağlı, and C. Kayaalp, “A case of Krukenberg tumor, eight years after treatment of gastric cancer”, Marmara Med J, vol. 31, no. 2, pp. 81–84, 2018, doi: 10.5472/marumj.430802.
ISNAD Karagül, Servet et al. “A Case of Krukenberg Tumor, Eight Years After Treatment of Gastric Cancer”. Marmara Medical Journal 31/2 (May 2018), 81-84. https://doi.org/10.5472/marumj.430802.
JAMA Karagül S, Sümer F, Onur A, Tardu A, Dağlı AF, Kayaalp C. A case of Krukenberg tumor, eight years after treatment of gastric cancer. Marmara Med J. 2018;31:81–84.
MLA Karagül, Servet et al. “A Case of Krukenberg Tumor, Eight Years After Treatment of Gastric Cancer”. Marmara Medical Journal, vol. 31, no. 2, 2018, pp. 81-84, doi:10.5472/marumj.430802.
Vancouver Karagül S, Sümer F, Onur A, Tardu A, Dağlı AF, Kayaalp C. A case of Krukenberg tumor, eight years after treatment of gastric cancer. Marmara Med J. 2018;31(2):81-4.