Year 2018, Volume 31 , Issue 1, Pages 33 - 40 2018-02-26

Anxiety and depression in patients with chronic obstructive pulmonary disease and their relation to serum vitamin D levels

Derya KOCAKAYA [1] , Sehnaz OLGUN YILDIZELI [2] , Ozan KOCAKAYA [3] , Huseyin ARIKAN [4] , Emel ERYUKSEL [5] , Emel ERYUKSEL [6]


Objectives: To determine whether serum vitamin D levels were

related to the prevalence of anxiety and depression among patients

with chronic obstructive pulmonary disease (COPD), as well as their

spirometry parameters, disease severity, and other clinical findings.

Materials and Methods: Ninety-two stable patients with

COPD aged over 18 years with no exacerbations in the previous

month were included. Symptom severity was assessed using the

modified Medical Research Council (mMRC) dyspnea scale and

COPD Assessment Test (CAT) scores. Spirometry tests were

performed and previous hospitalization histories were recorded

to determine ABCD groups of the patients according to their

combined COPD assessments. Their Body mass index, airflow

Obstruction, Dyspnea and Exercise capacity (BODE) indices were

calculated and the Hospital Anxiety and Depression Scale (HADS)

was administered. Serum vitamin D levels were determined using

immune electrochemiluminescence.

Results: According to the HADS scores, 16 patients (17.4%) had

the risk of anxiety and 29 (31.5%) had the risk of depression. The

risk of anxiety differed significantly (P= 0.016 Fischer’s exact test)

between the ABCD groups. Anxiety scores were positively correlated

with both mMRC (r= 0.315; P= 0.002) and CAT (r= 0.445; P= 0.000)

scores. Similarly, depression scores correlated positively with mMRC

(r= 0.249; P= 0.017) and CAT (r= 0.373; P= 0.000) scores. Neither

anxiety nor depression scores were significantly correlated with % of

predicted FEV1 (p= 0.339, P= 0.671). Serum vitamin D levels were

inversely correlated with anxiety (r= -0.215; P= 0.039) and depression

(r= -0.244; P= 0.019) scores. Anxiety scores were positively correlated

with BODE although not statistically significantly (r= 0.199; P= 0.058).

Conclusion: A negative correlation was revealed between

serum vitamin D levels and HADS scores, and symptom scores

were positively correlated to HADS scores, independent of % of

predicted FEV1.

Anxiety, Depression, Vitamin D, Chronic obstructive pulmonary disease
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Primary Language en
Subjects Medicine
Journal Section Articles
Authors

Author: Derya KOCAKAYA

Author: Sehnaz OLGUN YILDIZELI

Author: Ozan KOCAKAYA

Author: Huseyin ARIKAN

Author: Emel ERYUKSEL

Author: Emel ERYUKSEL

Dates

Publication Date : February 26, 2018

Bibtex @research article { marumj398936, journal = {Marmara Medical Journal}, issn = {1019-1941}, eissn = {1309-9469}, address = {}, publisher = {Marmara University}, year = {2018}, volume = {31}, pages = {33 - 40}, doi = {10.5472/marumj.398936}, title = {Anxiety and depression in patients with chronic obstructive pulmonary disease and their relation to serum vitamin D levels}, key = {cite}, author = {Kocakaya, Derya and Olgun Yıldızelı, Sehnaz and Kocakaya, Ozan and Arıkan, Huseyin and Eryuksel, Emel and Eryuksel, Emel} }
APA Kocakaya, D , Olgun Yıldızelı, S , Kocakaya, O , Arıkan, H , Eryuksel, E , Eryuksel, E . (2018). Anxiety and depression in patients with chronic obstructive pulmonary disease and their relation to serum vitamin D levels . Marmara Medical Journal , 31 (1) , 33-40 . DOI: 10.5472/marumj.398936
MLA Kocakaya, D , Olgun Yıldızelı, S , Kocakaya, O , Arıkan, H , Eryuksel, E , Eryuksel, E . "Anxiety and depression in patients with chronic obstructive pulmonary disease and their relation to serum vitamin D levels" . Marmara Medical Journal 31 (2018 ): 33-40 <https://dergipark.org.tr/en/pub/marumj/issue/33298/398936>
Chicago Kocakaya, D , Olgun Yıldızelı, S , Kocakaya, O , Arıkan, H , Eryuksel, E , Eryuksel, E . "Anxiety and depression in patients with chronic obstructive pulmonary disease and their relation to serum vitamin D levels". Marmara Medical Journal 31 (2018 ): 33-40
RIS TY - JOUR T1 - Anxiety and depression in patients with chronic obstructive pulmonary disease and their relation to serum vitamin D levels AU - Derya Kocakaya , Sehnaz Olgun Yıldızelı , Ozan Kocakaya , Huseyin Arıkan , Emel Eryuksel , Emel Eryuksel Y1 - 2018 PY - 2018 N1 - doi: 10.5472/marumj.398936 DO - 10.5472/marumj.398936 T2 - Marmara Medical Journal JF - Journal JO - JOR SP - 33 EP - 40 VL - 31 IS - 1 SN - 1019-1941-1309-9469 M3 - doi: 10.5472/marumj.398936 UR - https://doi.org/10.5472/marumj.398936 Y2 - 2017 ER -
EndNote %0 Marmara Medical Journal Anxiety and depression in patients with chronic obstructive pulmonary disease and their relation to serum vitamin D levels %A Derya Kocakaya , Sehnaz Olgun Yıldızelı , Ozan Kocakaya , Huseyin Arıkan , Emel Eryuksel , Emel Eryuksel %T Anxiety and depression in patients with chronic obstructive pulmonary disease and their relation to serum vitamin D levels %D 2018 %J Marmara Medical Journal %P 1019-1941-1309-9469 %V 31 %N 1 %R doi: 10.5472/marumj.398936 %U 10.5472/marumj.398936
ISNAD Kocakaya, Derya , Olgun Yıldızelı, Sehnaz , Kocakaya, Ozan , Arıkan, Huseyin , Eryuksel, Emel , Eryuksel, Emel . "Anxiety and depression in patients with chronic obstructive pulmonary disease and their relation to serum vitamin D levels". Marmara Medical Journal 31 / 1 (February 2018): 33-40 . https://doi.org/10.5472/marumj.398936
AMA Kocakaya D , Olgun Yıldızelı S , Kocakaya O , Arıkan H , Eryuksel E , Eryuksel E . Anxiety and depression in patients with chronic obstructive pulmonary disease and their relation to serum vitamin D levels. Marmara Med J. 2018; 31(1): 33-40.
Vancouver Kocakaya D , Olgun Yıldızelı S , Kocakaya O , Arıkan H , Eryuksel E , Eryuksel E . Anxiety and depression in patients with chronic obstructive pulmonary disease and their relation to serum vitamin D levels. Marmara Medical Journal. 2018; 31(1): 33-40.