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Papillary thyroid carcinoma after radioactive iodine treatment for toxic thyroid nodule: Case report

Year 2018, Volume: 31 Issue: 1, 50 - 53, 27.02.2018
https://doi.org/10.5472/marumj.399212

Abstract

Radioactive iodine (RAI) treatment is recommended as the first choice for toxic thyroid nodules by American Thyroid Association (ATA). Here, we present our second case of papillary thyroid carcinoma after RAI therapy. A fifty fiveyear-old woman received RAI therapy for toxic thyroid nodule in the right lobe in 2005. Pre-treatment fine needle aspiration biopsy (FNAB) revealed benign cytology. She was euthyroid after the therapy. However, 8 years after the treatment she had 15 mm thyroid nodule in the same location. This time, FNAB result was suspected for papillary thyroid carcinoma. The patient underwent bilateral total thyroidectomy and the histopathological evaluation revealed papillary thyroid carcinoma in the nodule. This is the second case with papillary carcinoma after RAI therapy. Papillary carcinoma developed after the RAI therapy. In conclusion, all cases should be closely followed up after RAI therapy for carcinoma development.

References

  • Mazzaferri EL. Management of a solitary thyroid nodule. N Eng J Med 1993;328:553-9. doi: 10.1056/ NEJM199302253280807
  • AACE/AME Guidelines. AACE/AME task force on thyroid nodules. American Association of Clinical Endocrinologist and Associaione Medici Endocrinologimedical guidelines for clinical practice for the diagnosis and management of thyroid nodules. Endocr Pract 2006;12:63-102.
  • Ziessman HA, O’malley JP, Thrall JH (Eds). Nuclear Medicine. Elsevier Mosby Philadelphia, PA: Elsevier Mosby,2006, 3-19.
  • Staffurth JS, Holl-Allen RTJ. Follicular carcinoma of the thyroid following radioactive iodine treatment for Graves’ disease. Postgrad Med J 1988;64:878-80. doi: 10.1136/pgmj.64.757.878
  • Maatouk J, Barklow TA, Zakaria W, Al-Abbadi MA. Anaplastic thyroid carcinoma arising in long-standing multinodular goiter following radioactive iodine therapy. Acta Cytol 2009;53:581-3. doi:10.1159/000325388
  • Cannizzaro MA, De Maria A, Fazzi C, et al. Anaplastic carcinoma of the thyroid: long-term survival. Minerva Chir 1993;48:1293-9.
  • Hayes FJ, Sheahan K, Heffernan A, McKenna TJ. Aggressive thyroid cancer associated with toxic nodular goiter. Eur J Endocrinol 1996;134:366-70. doi: 10.1530/eje.0.1340366
  • Vescini F, Di Gaetano P, Vigna E, Pascoli A, Cacciari M. Anaplastic thyroid carcinoma in a 49 year-old woman with a long-standing goiter: A case report. Minerva Endocrinol 2000;25:81-3.
  • Duran C, Cayci M, Kutlu O, et al. Papillary thyroid carcinoma developments after radioactive ıodine treatment for toxic adenoma: A Case Report. J Med Cases 2013;4:686-8. doi: 10.4021/jmc1459w
  • Rice, CO. Incidence of nodules in the thyroid. Arch Surg 1932; 24:505-15. doi:10.1001/archsurg.1932.01160150168008.
  • Mortensen JD, Woolner LB, Bennett WA. Gross and microscopic findings in clinically normal thyroid glands. J Clin Endocrinol Metab 1955;15:1270-80. doi:10.1210/jcem15-10-1270#sthash.4fB9a4TH.dpuf
  • Werk EE Jr, Vernon BM, Gonzalez JJ, Ungaro PC, McCoy RC. Cancer in thyroid nodules. A community hospital survey. Arch Intern Med 1984;144:474-76. doi:10.1001/ archinte.1984.00350150058018
  • Belfiore A, Giuffrida D, La Rosa GL, et al. High frequency of cancer in cold thyroid nodules occurring at young age. Acta Endocrinol (Copenh) 1989;121:197-202. Hegedüs L. Clinical practice. The thyroid nodule. N Engl J Med 2004;351:1764-71. doi: 10.1056/nejmcp031436
  • Lin JD, Chao TC, Huang BY, Chen ST, Chang HY, Hsueh C. Thyroid cancer in the thyroid nodules evaluated by ultrasonography and fine-needle aspiration cytology. Thyroid 2005;15:708-17. doi: 10.1089/thy.2005.15.708
  • Singer PA, Cooper DS, Daniels GH, et al. Treatment guidelines for patients with thyroid nodules and welldifferentiated thyroid cancer. American Thyroid Association. Arch Intern Med 1996;156:2165-72. doi:10.1001/ archinte.1996.00440180017002.

Toksik tiroit nodülü için radyoaktif iyot tedavisinden sonra gelişen tiroit papiller karsinomu: Olgu sunumu

Year 2018, Volume: 31 Issue: 1, 50 - 53, 27.02.2018
https://doi.org/10.5472/marumj.399212

Abstract

Amerikan Tiroit Derneği (ATA) toksik tiroit nodüllerinde ince iğne aspirasyon biyopsisi (İİAB) yapılmaksızın radyoaktif iyot (RAI) tedavisi önermektedir. Elli beş yaşında kadın hasta 2005 yılında tespit edilen tiroit sağ lobunda yerleşimli toksik nodül nedeniyle RAI tedavisi almış. Hastanın RAI öncesi yapılan İİAB sonucu benign tiroit nodülü olarak rapor edilmiş. Hastanın 8 yıl sonra yapılan kontrol ultrasonografisinde tiroit sağ lobda yerleşimli 15 mm çaplı solid nodül saptandı. Hastaya yapılan İİAB sonucu papiller karsinom açısından şüpheli olarak rapor edildi. Hastaya bilateral total tiroidektomi yapıldı. Histopatolojik incelemede nodülde papiller tiroit karsinomu tespit edildi. Bu vaka RAI sonrası karşılaştığımız ikinci papiller karsinom vakasıdır. Bu yazıda sunduğumuz olgu, RAI öncesi hastanın karsinomunun olmadığı ve kanser gelişiminin RAI tedavisi sonrası olduğu İİAB ile gösterilmiştir. Sonuç olarak, RAI tedavisi alan hastalar uzun dönemde karsinom gelişimi açısından yakın takip edilmelidir.

References

  • Mazzaferri EL. Management of a solitary thyroid nodule. N Eng J Med 1993;328:553-9. doi: 10.1056/ NEJM199302253280807
  • AACE/AME Guidelines. AACE/AME task force on thyroid nodules. American Association of Clinical Endocrinologist and Associaione Medici Endocrinologimedical guidelines for clinical practice for the diagnosis and management of thyroid nodules. Endocr Pract 2006;12:63-102.
  • Ziessman HA, O’malley JP, Thrall JH (Eds). Nuclear Medicine. Elsevier Mosby Philadelphia, PA: Elsevier Mosby,2006, 3-19.
  • Staffurth JS, Holl-Allen RTJ. Follicular carcinoma of the thyroid following radioactive iodine treatment for Graves’ disease. Postgrad Med J 1988;64:878-80. doi: 10.1136/pgmj.64.757.878
  • Maatouk J, Barklow TA, Zakaria W, Al-Abbadi MA. Anaplastic thyroid carcinoma arising in long-standing multinodular goiter following radioactive iodine therapy. Acta Cytol 2009;53:581-3. doi:10.1159/000325388
  • Cannizzaro MA, De Maria A, Fazzi C, et al. Anaplastic carcinoma of the thyroid: long-term survival. Minerva Chir 1993;48:1293-9.
  • Hayes FJ, Sheahan K, Heffernan A, McKenna TJ. Aggressive thyroid cancer associated with toxic nodular goiter. Eur J Endocrinol 1996;134:366-70. doi: 10.1530/eje.0.1340366
  • Vescini F, Di Gaetano P, Vigna E, Pascoli A, Cacciari M. Anaplastic thyroid carcinoma in a 49 year-old woman with a long-standing goiter: A case report. Minerva Endocrinol 2000;25:81-3.
  • Duran C, Cayci M, Kutlu O, et al. Papillary thyroid carcinoma developments after radioactive ıodine treatment for toxic adenoma: A Case Report. J Med Cases 2013;4:686-8. doi: 10.4021/jmc1459w
  • Rice, CO. Incidence of nodules in the thyroid. Arch Surg 1932; 24:505-15. doi:10.1001/archsurg.1932.01160150168008.
  • Mortensen JD, Woolner LB, Bennett WA. Gross and microscopic findings in clinically normal thyroid glands. J Clin Endocrinol Metab 1955;15:1270-80. doi:10.1210/jcem15-10-1270#sthash.4fB9a4TH.dpuf
  • Werk EE Jr, Vernon BM, Gonzalez JJ, Ungaro PC, McCoy RC. Cancer in thyroid nodules. A community hospital survey. Arch Intern Med 1984;144:474-76. doi:10.1001/ archinte.1984.00350150058018
  • Belfiore A, Giuffrida D, La Rosa GL, et al. High frequency of cancer in cold thyroid nodules occurring at young age. Acta Endocrinol (Copenh) 1989;121:197-202. Hegedüs L. Clinical practice. The thyroid nodule. N Engl J Med 2004;351:1764-71. doi: 10.1056/nejmcp031436
  • Lin JD, Chao TC, Huang BY, Chen ST, Chang HY, Hsueh C. Thyroid cancer in the thyroid nodules evaluated by ultrasonography and fine-needle aspiration cytology. Thyroid 2005;15:708-17. doi: 10.1089/thy.2005.15.708
  • Singer PA, Cooper DS, Daniels GH, et al. Treatment guidelines for patients with thyroid nodules and welldifferentiated thyroid cancer. American Thyroid Association. Arch Intern Med 1996;156:2165-72. doi:10.1001/ archinte.1996.00440180017002.
There are 15 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Case Reports
Authors

Barış Sevinç

Ömer Karahan This is me

Cevdet Duran This is me

Mustafa Çaycı This is me

Serden Ay This is me

Publication Date February 27, 2018
Published in Issue Year 2018 Volume: 31 Issue: 1

Cite

APA Sevinç, B., Karahan, Ö., Duran, C., Çaycı, M., et al. (2018). Papillary thyroid carcinoma after radioactive iodine treatment for toxic thyroid nodule: Case report. Marmara Medical Journal, 31(1), 50-53. https://doi.org/10.5472/marumj.399212
AMA Sevinç B, Karahan Ö, Duran C, Çaycı M, Ay S. Papillary thyroid carcinoma after radioactive iodine treatment for toxic thyroid nodule: Case report. Marmara Med J. January 2018;31(1):50-53. doi:10.5472/marumj.399212
Chicago Sevinç, Barış, Ömer Karahan, Cevdet Duran, Mustafa Çaycı, and Serden Ay. “Papillary Thyroid Carcinoma After Radioactive Iodine Treatment for Toxic Thyroid Nodule: Case Report”. Marmara Medical Journal 31, no. 1 (January 2018): 50-53. https://doi.org/10.5472/marumj.399212.
EndNote Sevinç B, Karahan Ö, Duran C, Çaycı M, Ay S (January 1, 2018) Papillary thyroid carcinoma after radioactive iodine treatment for toxic thyroid nodule: Case report. Marmara Medical Journal 31 1 50–53.
IEEE B. Sevinç, Ö. Karahan, C. Duran, M. Çaycı, and S. Ay, “Papillary thyroid carcinoma after radioactive iodine treatment for toxic thyroid nodule: Case report”, Marmara Med J, vol. 31, no. 1, pp. 50–53, 2018, doi: 10.5472/marumj.399212.
ISNAD Sevinç, Barış et al. “Papillary Thyroid Carcinoma After Radioactive Iodine Treatment for Toxic Thyroid Nodule: Case Report”. Marmara Medical Journal 31/1 (January 2018), 50-53. https://doi.org/10.5472/marumj.399212.
JAMA Sevinç B, Karahan Ö, Duran C, Çaycı M, Ay S. Papillary thyroid carcinoma after radioactive iodine treatment for toxic thyroid nodule: Case report. Marmara Med J. 2018;31:50–53.
MLA Sevinç, Barış et al. “Papillary Thyroid Carcinoma After Radioactive Iodine Treatment for Toxic Thyroid Nodule: Case Report”. Marmara Medical Journal, vol. 31, no. 1, 2018, pp. 50-53, doi:10.5472/marumj.399212.
Vancouver Sevinç B, Karahan Ö, Duran C, Çaycı M, Ay S. Papillary thyroid carcinoma after radioactive iodine treatment for toxic thyroid nodule: Case report. Marmara Med J. 2018;31(1):50-3.