The seasonality in the diagnosis of acute leukemia: A single center data from Turkey

Year 2018, Volume: 31 Issue: 3, 112 - 115, 31.10.2018

Rafet Eren , Mehmet Hilmi Doğu Şermin Altındal Osman Yokuş Elif Suyanı

https://doi.org/10.5472/marumj.474176

Abstract

Objectives: The seasonality in the diagnosis of acute leukemias

(ALs) has been conceived ever since and the results have been

confounding between summer and winter peaks since those times.

To our knowledge, the seasonality in the diagnosis ALs has not

been explored in our region and we aimed to investigate for a

seasonal accumulation in the diagnosis of AL patients.

Materials and Methods: A hundred and sixty-two patients

who were diagnosed with either acute myeloid leukemia (AML)

or acute lymphocytic leukemia (ALL) between November 2012

and October 2017 were included in the study. The data regarding

the gender, age, type of leukemia and the time of admission were

noted from files of the patients.

Results: The median age of the patients was 51.5 years (range,

17-85) with 64 (39.5%) female, 98 (60.5%) male. Most of AL

patients were diagnosed in August (21,13%) and the least in June

with 6 (3.7%) patients. According to the seasons; 39 (24.1%)

patients were diagnosed in winter, 40 (24.7%) patients in spring,

40 (24.7%) patients in summer and 43 (26.5%) patients in autumn

(P>0.05).

Conclusion: We could not determine any seasonality in the

diagnosis of ALs, both AML and ALL, in our study.

Keywords

Acute myeloid leukemia, Acute lymphoblastic leukemia, Seasonality

Akut lösemi tanısında mevsimsel dağılım: Türkiye’den tek merkez verisi

Abstract

Amaç: Akut lösemilerin (AL) tanısında mevsimsel değişkenlik

olabileceği uzun süredir düşünülüyor olsa da yapılan çalışmaların

sonuçları yaz ve kış pikleri arasında çelişkilidir. Bilindiği kadarıyla

bölgemizde AL tanısında mevsimsel değişkenlik incelenmemiştir.

Bu çalışmada AL hastalarının tanısında mevsimsel bir birikim olup

olmadığını araştırmayı amaçladık.

Yöntemler ve Gereçler: Kasım 2012 ile Ekim 2017 tarihleri

arasında akut myeloid lösemi (AML) veya akut lenfositik lösemi

(ALL) tanısı alan 162 hasta çalışmaya dâhil edildi. Cinsiyet, yaş,

lösemi tipi ve hastaneye yatış bilgileri hasta dosyalarından edinildi.

Bulgular: Hastaların medyan yaşı 51,5 idi (aralık: 17-85). 64

hasta (%39,5) kadın, 98’i ise (%60,5) erkekti. AL tanısı alan 21

hasta (%13) ile en sık Ağustos ayında iken, 6 hasta (%3,7) ile en

nadir Haziran ayındaydı. Mevsimlere göre incelendiğinde, 39 hasta

(%24,1) kış, 40 hasta (%24,7) ilkbahar, 40 hasta (%24,7) yaz ve 43

hasta (%26,5) ise sonbahar mevsiminde tanı almıştı (P>0,05).

Sonuç: Hem AML hem de ALL açısından bakıldığında,

çalışmamızda AL tanısında herhangi bir mevsimsel değişkenlik

belirleyemedik.

Keywords

Akut myeloid lösemi, Akut lenfoblastik lösemi, Mevsimsel dağılım

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