Year 2012,
Volume: 25 Issue: 2, 69 - 73, 17.03.2015
Tevfik Yoldemir
Mithat Erenus
References
- 1. Bancsi LF, Broekmans FJ, Eijkemans MJ, de Jong FH, Habbema JD, te Velde ER. Predictors of poor ovarian response in in vitro fertilization: a prospective study comparing basal markers of ovarian reserve. Fertil Steril 2002;77:328-36. doi: 10.1016/S0015-0282(01)02983-1
- 2. Hendriks DJ, Mol BW, Bancsi LF, te Velde ER, Broekmans FJ. Antral follicle count in the prediction of poor ovarian response and pregnancy after in vitro fertilization: a meta-analysis and comparison with basal folliclestimulating hormone level. Fertil Steril 2005;83: 291-301. doi:10.1016/j.fertnstert.2004.10.011
- 3. Broekmans FJ, Kwee J, Hendriks DJ, Mol BW, Lambalk CB. A systematic review of tests predicting ovarian reserve and IVF outcome. Hum Reprod Update 2006;12:685-718. doi:10.1093/humupd/dml034
- 4. Mol BW, Verhagen TE, Hendriks DJ, et al. Value of ovarian reserve testing before IVF: a clinical decision analysis. Hum Reprod 2006;21:1816-23.
- 5. Muasher SJ, Oehninger S, Simonetti S. The value of basal and/or stimulated serum gonadotropin levels in prediction of stimulation response and in vitro fertilization outcome. Fertil Steril 1998;50:298-307.
- 6. Tanbo T, Dale P O, Lunde O. Prediction of response to controlled ovarian hyperstimulation: a comparison of basal and clomiphene citratestimulated follicle-stimulating hormone levels. Fertil Steril 1992;57:819-24.
- 7. Winslow KL, Toner JP, Brzyski RG. The gonadotrophin releasing hormone agonist stimulation test - a sensitive predictor of performance in the flareup in vitro fertilization cycle. Fertil Steril 1991;56:711-17.
- 8. Franchin R, De Ziegler D, Olivennes F. Exogenous follicle stimulating hormone ovarian reserve test (EFORT): a simple and reliable screening test for detecting ‘poor responders’ in in vitro fertilization. Hum Reprod 1994; 9:1607-11.
- 9. Smotrich DB., Widra EA, Gindoff PR. Prognostic value of day 3 estradiol on in vitro fertilization outcome. Fertil Steril 1995; 64: 1136-40.
- 10. Van er Spuy ZM, Alberts PJ. Ovarian reserve. In: Healy DL, Kovacs GT, McLachlan R, Rodriguez-Armas O, eds. Reproductive Medicine in the Twenty-First Century. London: Parthenon, 2002; 295-305.
- 11. Sharara FI, Scott RT Jr , Seifer DB. The detection of diminished ovarian reserve in infertile women. Am J Obstet Gynecol 1998; 179: 804-12.
- 12. Licciardi FL, Liu HC, Rosenwaks Z. Day 3 estradiol serum concentrations as prognosticators of ovarian stimulation response and pregnancy outcome in patients undergoing in vitro fertilization. Fertil Steril 1995;64:991-4.
- 13. Tarlatzis BC, Zepiridis L, Grimbizis G, Bontis J. Clinical management of low ovarian response to stimulation for IVF: a systematic review. Hum Reprod Update 2003;9:61-76. doi: 10.1093/humupd/dmg007
- 14. Barnhart K, Osherhoff J. Follicule stimulating hormone as a predictor of fertility. Curr Opin Obstet Gynecol 1998;10:227-32.
- 15. Fasouliotis SJ, Simon A, Laufer N. Evaluation and treatment of low responders in assisted reproductive technology: a challenge to meet. J Assist Reprod Genet 2000;17:357-73. doi: 10.1023/A:1009465324197
- 16. Bukman A., Heineman MJ. Ovarian reserve testing and the use of prognostic models in patients with subfertility Hum Reprod Update 2001;7:581-90. doi: 10.1093/humupd/7.6.581
- 17. Creus M, Peñarrubia J, Fábregues F, et al. Day 3 serum inhibin B and FSH and age as predictors of assisted reproduction treatment outcome Hum Reprod 2000;15:2341-6. doi: 10.1093/humrep/15.11.2341
- 18. Lass A, Gerrard A, Abusheikha N, Akagbosu F, Brinsden P. IVF performance of women who have fluctuating early follicular FSH levels. J Assist Reprod Genet 2000;17:566-73.
- 19. Peñarrubia J, Balasch J, Fábregues F, et al. Day 5 inhibin B serum concentrations as predictors of assisted reproductive technology outcome in cycles stimulated with gonadotrophin-releasing hormone agonistgonadotrophin treatment. Hum Reprod 2000;15:1499-504. doi: 10.1093/humrep/15.7.1499
- 20. Scott RT Jr, Hofmann GE, Oehninger S, Muasher SJ. Intercycle variability of day 3 follicle-stimulating hormone levels and its effect on stimulation quality in in vitro fertilization. Fertil Steril 1990;54:297-302.
- 21. Martin JS, Nisker JA, Tummon IS, Daniel SA, Auckland JL, Feyles V. Future in vitro fertilization pregnancy potential of women with variably elevated day 3 follicle-stimulating hormone levels. Fertil Steril 1996;65:1238-40.
- 22. Mukherjee T, Copperman AB, Lapinski R, Sandler B, Bustillo M, Grunfeld L. An elevated day three follicle-stimulating hormone:luteinizing hormone ratio (FSH:LH) in the presence of a normal day 3 FSH predicts a poor response to controlled ovarian hyperstimulation. Fertil Steril 1996;65:588-93.
- 23. Barroso G, Oehninger S, Monzo A, Kolm P, Gibbons WE, Muasher SJ. High FSH:LH ratio and low LH levels in basal cycle day 3: impact on follicular development and IVF outcome. J Assist Reprod Genet 2001;18:499-505. doi: 10.1093/humrep/dep254
- 24. Shrim A, Elizur SE, Seidman DS, Rabinovici J,Wiser A, Dor J. Elevated day 3 FSH/LH ratio due to low LH concentrations predicts reduced ovarian response. Reprod Biomed Online 2006;12:418-22.
- 25. Noci I, Biagiotti R, Maggi M, Ricci F, Cinotti A, Scarselli G. Low day 3 luteinizing hormone values are predictive of reduced response to ovarian stimulation. Hum Reprod 1998;13:531-4. doi: 10.1093/humrep/ 14.3.863
- 26. Mukherjee T, Copperman AB, Rosen T. Low day three LH in the presence of a normal baseline FSH predicts a poor response to controlled ovarian hyperstimulation. Abstracts, 51st Annual Meeting of the American Society for Reproductive Medicine, October 7-12, 1995, Seattle, Washington, USA, abstract 0-020:511.
- 27. Bosch E, Escudero E, Crespo J, Simon C, Remohi J, Pellicer A. Serum luteinizing hormone in patients undergoing ovarian stimulation with gonadotropin-releasing hormone antagonists and recombinant folliclestimulating hormone and its relationship with cycle outcome. Fertil Steril 2005;84:1529-32. doi:10.1016/j.fertnstert.2005.05.040
- 28. Kolibianakis EM, Collins J, Tarlatzis B, Papanikolaou E, Devroey P. Are endogenous LH levels during ovarian stimulation for IVF using GnRH analogues associated with the probability of ongoing pregnancy? A systematic review. Hum Reprod Update 2006;12:3-12. doi: 10.1093/humupd/dmi030
- 29. Liu KE, Greenblatt EM. Elevated day 3 follicle-stimulating hormone/ luteinizing hormone ratio ≥ 2 is associated with higher rates of cancellation in in vitro fertilization-embryo transfer cycles. Fertil Steril 2008;90:297-301.
Siklusun 3.Günü Normal FSH Değeri Olan Kadınlarda FSH/LH Oranı ICSI Başarısını Öngörebilir mi?
Year 2012,
Volume: 25 Issue: 2, 69 - 73, 17.03.2015
Tevfik Yoldemir
Mithat Erenus
Abstract
Amaç: Siklusun 3.günü normal FSH değeri olan kadınlarda follikül stimule
edici hormon (FSH)/luteinize edici hormon (LH) oranının sitoplazma içi
sperm enjeksiyonu (ICSI) başarısının öngörülebilirliğini araştırmak.
Hastalar ve Yöntem: Uzun protokol ve rekombinant folikül stimüle edici
hormon kullanılarak ICSI tedavisi alan ardışık yüz doksan dokuz infertil kadın
retrospektif olarak analiz edildi. Grup A, B, C ve D sırasıyla FSH/LH oranları
< 1; ≥ 1 ile < 1.5 arası; ≥ 1.5 ile ≤ 2 arası ve > 2 olan kadınlardan oluşturuldu.
Transfer başına klinik gebelik ve implantasyon oranları karşılaştırıldı.
Bulgular: Transfer başına klinik gebelik ve implantasyon oranları gruplar arasında
benzer idi.
Sonuç: Siklusun 3.günü FSH/LH oranı ICSI sikluslarında tedavi sonuçlarını
normal 3. gün FSH seviyesi olan kadınlarda öngöremez.
References
- 1. Bancsi LF, Broekmans FJ, Eijkemans MJ, de Jong FH, Habbema JD, te Velde ER. Predictors of poor ovarian response in in vitro fertilization: a prospective study comparing basal markers of ovarian reserve. Fertil Steril 2002;77:328-36. doi: 10.1016/S0015-0282(01)02983-1
- 2. Hendriks DJ, Mol BW, Bancsi LF, te Velde ER, Broekmans FJ. Antral follicle count in the prediction of poor ovarian response and pregnancy after in vitro fertilization: a meta-analysis and comparison with basal folliclestimulating hormone level. Fertil Steril 2005;83: 291-301. doi:10.1016/j.fertnstert.2004.10.011
- 3. Broekmans FJ, Kwee J, Hendriks DJ, Mol BW, Lambalk CB. A systematic review of tests predicting ovarian reserve and IVF outcome. Hum Reprod Update 2006;12:685-718. doi:10.1093/humupd/dml034
- 4. Mol BW, Verhagen TE, Hendriks DJ, et al. Value of ovarian reserve testing before IVF: a clinical decision analysis. Hum Reprod 2006;21:1816-23.
- 5. Muasher SJ, Oehninger S, Simonetti S. The value of basal and/or stimulated serum gonadotropin levels in prediction of stimulation response and in vitro fertilization outcome. Fertil Steril 1998;50:298-307.
- 6. Tanbo T, Dale P O, Lunde O. Prediction of response to controlled ovarian hyperstimulation: a comparison of basal and clomiphene citratestimulated follicle-stimulating hormone levels. Fertil Steril 1992;57:819-24.
- 7. Winslow KL, Toner JP, Brzyski RG. The gonadotrophin releasing hormone agonist stimulation test - a sensitive predictor of performance in the flareup in vitro fertilization cycle. Fertil Steril 1991;56:711-17.
- 8. Franchin R, De Ziegler D, Olivennes F. Exogenous follicle stimulating hormone ovarian reserve test (EFORT): a simple and reliable screening test for detecting ‘poor responders’ in in vitro fertilization. Hum Reprod 1994; 9:1607-11.
- 9. Smotrich DB., Widra EA, Gindoff PR. Prognostic value of day 3 estradiol on in vitro fertilization outcome. Fertil Steril 1995; 64: 1136-40.
- 10. Van er Spuy ZM, Alberts PJ. Ovarian reserve. In: Healy DL, Kovacs GT, McLachlan R, Rodriguez-Armas O, eds. Reproductive Medicine in the Twenty-First Century. London: Parthenon, 2002; 295-305.
- 11. Sharara FI, Scott RT Jr , Seifer DB. The detection of diminished ovarian reserve in infertile women. Am J Obstet Gynecol 1998; 179: 804-12.
- 12. Licciardi FL, Liu HC, Rosenwaks Z. Day 3 estradiol serum concentrations as prognosticators of ovarian stimulation response and pregnancy outcome in patients undergoing in vitro fertilization. Fertil Steril 1995;64:991-4.
- 13. Tarlatzis BC, Zepiridis L, Grimbizis G, Bontis J. Clinical management of low ovarian response to stimulation for IVF: a systematic review. Hum Reprod Update 2003;9:61-76. doi: 10.1093/humupd/dmg007
- 14. Barnhart K, Osherhoff J. Follicule stimulating hormone as a predictor of fertility. Curr Opin Obstet Gynecol 1998;10:227-32.
- 15. Fasouliotis SJ, Simon A, Laufer N. Evaluation and treatment of low responders in assisted reproductive technology: a challenge to meet. J Assist Reprod Genet 2000;17:357-73. doi: 10.1023/A:1009465324197
- 16. Bukman A., Heineman MJ. Ovarian reserve testing and the use of prognostic models in patients with subfertility Hum Reprod Update 2001;7:581-90. doi: 10.1093/humupd/7.6.581
- 17. Creus M, Peñarrubia J, Fábregues F, et al. Day 3 serum inhibin B and FSH and age as predictors of assisted reproduction treatment outcome Hum Reprod 2000;15:2341-6. doi: 10.1093/humrep/15.11.2341
- 18. Lass A, Gerrard A, Abusheikha N, Akagbosu F, Brinsden P. IVF performance of women who have fluctuating early follicular FSH levels. J Assist Reprod Genet 2000;17:566-73.
- 19. Peñarrubia J, Balasch J, Fábregues F, et al. Day 5 inhibin B serum concentrations as predictors of assisted reproductive technology outcome in cycles stimulated with gonadotrophin-releasing hormone agonistgonadotrophin treatment. Hum Reprod 2000;15:1499-504. doi: 10.1093/humrep/15.7.1499
- 20. Scott RT Jr, Hofmann GE, Oehninger S, Muasher SJ. Intercycle variability of day 3 follicle-stimulating hormone levels and its effect on stimulation quality in in vitro fertilization. Fertil Steril 1990;54:297-302.
- 21. Martin JS, Nisker JA, Tummon IS, Daniel SA, Auckland JL, Feyles V. Future in vitro fertilization pregnancy potential of women with variably elevated day 3 follicle-stimulating hormone levels. Fertil Steril 1996;65:1238-40.
- 22. Mukherjee T, Copperman AB, Lapinski R, Sandler B, Bustillo M, Grunfeld L. An elevated day three follicle-stimulating hormone:luteinizing hormone ratio (FSH:LH) in the presence of a normal day 3 FSH predicts a poor response to controlled ovarian hyperstimulation. Fertil Steril 1996;65:588-93.
- 23. Barroso G, Oehninger S, Monzo A, Kolm P, Gibbons WE, Muasher SJ. High FSH:LH ratio and low LH levels in basal cycle day 3: impact on follicular development and IVF outcome. J Assist Reprod Genet 2001;18:499-505. doi: 10.1093/humrep/dep254
- 24. Shrim A, Elizur SE, Seidman DS, Rabinovici J,Wiser A, Dor J. Elevated day 3 FSH/LH ratio due to low LH concentrations predicts reduced ovarian response. Reprod Biomed Online 2006;12:418-22.
- 25. Noci I, Biagiotti R, Maggi M, Ricci F, Cinotti A, Scarselli G. Low day 3 luteinizing hormone values are predictive of reduced response to ovarian stimulation. Hum Reprod 1998;13:531-4. doi: 10.1093/humrep/ 14.3.863
- 26. Mukherjee T, Copperman AB, Rosen T. Low day three LH in the presence of a normal baseline FSH predicts a poor response to controlled ovarian hyperstimulation. Abstracts, 51st Annual Meeting of the American Society for Reproductive Medicine, October 7-12, 1995, Seattle, Washington, USA, abstract 0-020:511.
- 27. Bosch E, Escudero E, Crespo J, Simon C, Remohi J, Pellicer A. Serum luteinizing hormone in patients undergoing ovarian stimulation with gonadotropin-releasing hormone antagonists and recombinant folliclestimulating hormone and its relationship with cycle outcome. Fertil Steril 2005;84:1529-32. doi:10.1016/j.fertnstert.2005.05.040
- 28. Kolibianakis EM, Collins J, Tarlatzis B, Papanikolaou E, Devroey P. Are endogenous LH levels during ovarian stimulation for IVF using GnRH analogues associated with the probability of ongoing pregnancy? A systematic review. Hum Reprod Update 2006;12:3-12. doi: 10.1093/humupd/dmi030
- 29. Liu KE, Greenblatt EM. Elevated day 3 follicle-stimulating hormone/ luteinizing hormone ratio ≥ 2 is associated with higher rates of cancellation in in vitro fertilization-embryo transfer cycles. Fertil Steril 2008;90:297-301.