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Year 2011, Volume: 24 Issue: 1, 59 - 63, 21.04.2015

Abstract

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References

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  • arylesterase activity in children. Clin Chim Acta
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  • -
  • Ecobichon DJ, Stephens DS. Perinatal
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  • Suehiro T, Nakanchi Y, Yammamoto M, Arii K, Itoh
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  • polymorphism in Japanese subjects with coronary
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  • 1016/S0167-5273(96)02779-9
  • Antikainen M, Mutomaki S, Syvanne M, Pahlman R,
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  • polymorphism of human paraoxonase gene
  • (HUMPONA) is not associated with the risk of
  • coronary artery disease in Finns. J Clin Invest
  • ;98:883-885.
  • Mukamal KJ, Pai JK, Jensen MK, Rimm EB.
  • Paraoxonase 1 polymorphisms and risk of
  • myocardial infarction in women and men. Circ J
  • ;73(7):1302-1307. doi: 10.1253/circj.CJ-08-
  • -
  • Rios DL, D’Onofrio LO, Cerqueira CC, Bonfim-Silva
  • R, Carvalho HG, Santos-Filho A, et al. Paraoxonase
  • gene polymorphisms in angiographically
  • assessed coronary artery disease: evidence for
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  • Lab Med 2007;45:874-878. doi:
  • 1515/CCLM.2007.136
  • Sanghera DK, Saha N, Aston CE, Kamboh MI.
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  • of coronary heart disease. Arterioscler Thromb
  • Vasc Biol 1997;17:1067-1073.
  • Ruiz J, Blanche H, James RW, Garin MC, Vaisse C,
  • CharpentierG, Cohen N, Morabia A, Passa P,
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  • Ö. TARÇIN
  • Paraoksonaz-1 ve koroner kalp hastalığı
  • Marmara Medical Journal 2011; 24 (1):59-63
  • -
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  • doi:10.1016/S0140-6736(95)92709-3
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  • A preliminary study of human paraoxonase and
  • PON1 L/M55-PON1 Q/R192 polymorphisms in
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  • 1002/cbf.1539
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  • Turkish patients with coronary artery disease. Int J
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  • paraoxonase (PON) enzyme in the extent and
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  • doi: 10.1007/s00380-0060957-6
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  • effect of paraoxonase activity in high-density
  • lipoproteins against erythrocyte membranes
  • peroxidation: a comparison between healthy
  • subjects and type 1 diabetic patients. J Clin
  • Endocrinol Metab 2004;89:2957-2962.
  • Karabina SA, Lehner AN, Franke E, Parthasara S,
  • Santanam N. Oxidative inactivation of paraoxonaseimplications
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Paraoksonaz-1 Enzimi ve Koroner Kalp Hastalıkları ile İlişkisi

Year 2011, Volume: 24 Issue: 1, 59 - 63, 21.04.2015

Abstract

Anti-oksidan bir enzim olan paraoksonaz-1(PON1) enzim düzeyi ve aktivitesi, koroner arter hastalığı ile ilişkili olan hipertansiyon, diyabet, hiperlipidemi ve sigara kullanımı ile azalmaktadır. Tüm çalışmalar anjiografik olarak koroner arter hastalığı(KAH) kanıtlanmış olan hastalarda PON1 düzeyinin düştüğünü göstermektedir. Ancak polimorfizm açısından net olarak tek bir polimorfizm ile ilişkisi gösterilememiştir. Bu bilgilerin ışığında PON1 enzim düzeyi, KAH gelişimi açısından belirleyici bir marker olabilir. Ancak bunun klinik olarak kanıtlanması için prospektif ve kontrollü çalışmalara ihtiyaç vardır.

Anahtar Kelimeler: Paraoksonaz-1, Koroner kalp hastalıkları, PON1 polimorfizm

References

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  • gene (PON1) is one member of a multigene family.
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  • 1006/geno.1996.0225
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  • serum “A”-esterase activity into the lipoprotein
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  • paraoxonase-3 is an HDL-associated enzyme with
  • biological activity similar to paraoxonase-1 protein
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  • Thromb Vasc Biol 2001;21:542-547.
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  • missense polymorphisms in the coding sequence.
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  • paraoxonase (PON1) activity. Biochem Pharmacol
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  • Aviram M, Rosenbalt M. Paraoxonases and
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  • polymorphism in Japanese subjects with coronary
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  • 1016/S0167-5273(96)02779-9
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  • polymorphism of human paraoxonase gene
  • (HUMPONA) is not associated with the risk of
  • coronary artery disease in Finns. J Clin Invest
  • ;98:883-885.
  • Mukamal KJ, Pai JK, Jensen MK, Rimm EB.
  • Paraoxonase 1 polymorphisms and risk of
  • myocardial infarction in women and men. Circ J
  • ;73(7):1302-1307. doi: 10.1253/circj.CJ-08-
  • -
  • Rios DL, D’Onofrio LO, Cerqueira CC, Bonfim-Silva
  • R, Carvalho HG, Santos-Filho A, et al. Paraoxonase
  • gene polymorphisms in angiographically
  • assessed coronary artery disease: evidence for
  • gender interaction among Brazilians. Clin Chem
  • Lab Med 2007;45:874-878. doi:
  • 1515/CCLM.2007.136
  • Sanghera DK, Saha N, Aston CE, Kamboh MI.
  • Genetic polymorphism of paraoxonase and the risk
  • of coronary heart disease. Arterioscler Thromb
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  • Ö. TARÇIN
  • Paraoksonaz-1 ve koroner kalp hastalığı
  • Marmara Medical Journal 2011; 24 (1):59-63
  • -
  • paraoxonase and coronary heart disease in type 2
  • diabetes. Lancet 1995;346(8979):869-872.
  • doi:10.1016/S0140-6736(95)92709-3
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  • A preliminary study of human paraoxonase and
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  • Turkish patients with coronary artery disease. Cell
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  • 1002/cbf.1539
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  • Kara İ. Combined impact of matrix
  • metalloproteinase-3 and paraoxonase 1 55/192
  • gene variants on coronary artery disease in Turkish
  • Patients. Med Sci Monit 2008;14(19):536-542.
  • Aynacıoğlu AS, Kepekçi Y. The human
  • paraoxonase Gln-Arg 192(Q/R) polymorphism in
  • Turkish patients with coronary artery disease. Int J
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  • (00)00242-4
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  • severity of the coronary artery disease in type-2
  • diabetic patients. Heart Vessels 2007;22(3):158-
  • doi: 10.1007/s00380-0060957-6
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  • effect of paraoxonase activity in high-density
  • lipoproteins against erythrocyte membranes
  • peroxidation: a comparison between healthy
  • subjects and type 1 diabetic patients. J Clin
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  • Karabina SA, Lehner AN, Franke E, Parthasara S,
  • Santanam N. Oxidative inactivation of paraoxonaseimplications
  • in diabetes mellitus and
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There are 267 citations in total.

Details

Primary Language Turkish
Journal Section Review Makaleler
Authors

Özlem Tarçın

Publication Date April 21, 2015
Published in Issue Year 2011 Volume: 24 Issue: 1

Cite

APA Tarçın, Ö. (2015). Paraoksonaz-1 Enzimi ve Koroner Kalp Hastalıkları ile İlişkisi. Marmara Medical Journal, 24(1), 59-63.
AMA Tarçın Ö. Paraoksonaz-1 Enzimi ve Koroner Kalp Hastalıkları ile İlişkisi. Marmara Med J. August 2015;24(1):59-63.
Chicago Tarçın, Özlem. “Paraoksonaz-1 Enzimi Ve Koroner Kalp Hastalıkları Ile İlişkisi”. Marmara Medical Journal 24, no. 1 (August 2015): 59-63.
EndNote Tarçın Ö (August 1, 2015) Paraoksonaz-1 Enzimi ve Koroner Kalp Hastalıkları ile İlişkisi. Marmara Medical Journal 24 1 59–63.
IEEE Ö. Tarçın, “Paraoksonaz-1 Enzimi ve Koroner Kalp Hastalıkları ile İlişkisi”, Marmara Med J, vol. 24, no. 1, pp. 59–63, 2015.
ISNAD Tarçın, Özlem. “Paraoksonaz-1 Enzimi Ve Koroner Kalp Hastalıkları Ile İlişkisi”. Marmara Medical Journal 24/1 (August 2015), 59-63.
JAMA Tarçın Ö. Paraoksonaz-1 Enzimi ve Koroner Kalp Hastalıkları ile İlişkisi. Marmara Med J. 2015;24:59–63.
MLA Tarçın, Özlem. “Paraoksonaz-1 Enzimi Ve Koroner Kalp Hastalıkları Ile İlişkisi”. Marmara Medical Journal, vol. 24, no. 1, 2015, pp. 59-63.
Vancouver Tarçın Ö. Paraoksonaz-1 Enzimi ve Koroner Kalp Hastalıkları ile İlişkisi. Marmara Med J. 2015;24(1):59-63.