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Year 2014, Volume: 27 Issue: 3, 207 - 209, 30.03.2015
https://doi.org/10.5472/MMJ.2014.03283.1

Abstract

Even though adnexal masses are detected during pregnancy ranging from 1 to 81 to 1 in 2.500 pregnancies, only 3% of these are malignant. A Krukenberg tumor is an ovarian metastasis of a gastric tumor and accounts for 1-2% of all ovarian tumors. A 29-year-old woman, gravida 3, para 2, was referred to our unit at 20 weeks’ gestation because of epigastric pain for the last one week. Her abdominal ultrasound revealed a singleton pregnancy, with fetal measurements compatible with 20 weeks of gestation. A solid mass of 12.8 cm by 12 cm localized posterior to the uterus extending to both adnexial regions was also detected. Under general anesthesia, a midline abdominal incision was made. During abdominal inspection the gravid uterus was the size appropriate for the current gestational week. A 12 cm by 13 cm mass originating from the right ovary was excised. Then, a 17 cm by 18 cm mass originating from the left ovary was excised. The final pathology report confirmed positive washing cytology and a metastastic adenocarcinoma of both ovaries. Three weeks later, the woman had a gastroscopic biopsy and the pathology report was of an adenocarcinoma of the stomach. Unfortunately, the woman was lost to follow-up

References

  • 1. Singhal SR, Nanda S, Chaudhry P, Sen P, Singhal SK. Metastatic bilateral malignant ovarian tumors associated with pregnancy. Taiwan J Obstet Gynecol 2009; 48:167–8. doi:10.1016/S1028-4559(09)60280-1
  • 2. Tamussino K, Scholl W, Reich O, Winter R. Gastric carcinoma presenting as a Krukenberg tumor in the 24th week of gestation. Eur J Obstet Gynecol Reprod Biol 1995;62:251–2. doi: 10.1016/0301-2115(95)02179-B
  • 3. Stojnic J, Stefanovic A, Jeremic K, Kadija S, Jeftovic M, Jeremic J. Krukenberg tumor of gastric origin in pregnancy with dismal outcome. Eur J Gynaecol Oncol 2011;32:356-8.
  • 4. Genç M, Genç B, Solak A, Gür E, Sezgin C. Bilateral Krukenberg tumor in a 16-week pregnant woman. Eur J Gynaecol Oncol 2014;35:95-6.
  • 5. McGill FM, Ritter DB, Rickard CS, et al. Krukenberg tumors: can management be improved? Gynecol Obstet Invest 1999;48:61–5.
  • 6. Antonelli NM, Dotters DJ, Katz VL, Kuller JA. Cancer in pregnancy: a review of the literature. Part I. Obstet Gynecol Surv 1996;51:125–34.
  • 7. Shimizu H, Yamasaki M, Ohama K, Tadaharu N, Tanaka Y. Characteristic ultrasonographic appearance of the Krukenberg tumor. J Clin Ultrasound 1990;18:697–703.
  • 8. Choi BI, Choo IW, Han MC, Kim CW. Sonographic appearance of Krukenberg tumor from gastric carcinoma. Gastrointest Radiol 1988;13:15–8.
  • 9. Megibow AJ, Hulnick DH, Bosniak MA, Balthazar EJ. Ovarian metastases: computed tomographic appearances. Radiology 1985;156:161–4.
  • 10. Papakonstantinou E, Liapis A, Kairi-Vassilatou E, Iavazzo C, Kleanthis CK, Kondi-Pafiti A. Virilizing ovarian Krukenberg tumor in a 27-year-old pregnant woman. A case report and literature review. Eur J Gynaecol Oncol 2011;32:331-3.
  • 11. Sandmeier D, Lobrinus JA, Vial Y, Delaloye JF, Genton CY. Bilateral Krukenberg tumor of the ovary during pregnancy. Eur J Gynaecol Oncol 2000;21: 58–60.
  • 12. Due˜nas-Garcia OF, Diaz-Sotomayor M, Chanana C. Bilateral ovarian Krukenberg tumor in a full-term pregnancy. ISRN Obstet Gynecol 2011;2011:620380. doi:10.5402/2011/620380

İkinci trimesterde bilateral ovaryen Krukenberg tumörü

Year 2014, Volume: 27 Issue: 3, 207 - 209, 30.03.2015
https://doi.org/10.5472/MMJ.2014.03283.1

Abstract

Gebelikte adneksiyal kitleler 1/81 ile 1/2,500 sıklıkta görülse de bunların sadece %3’ü maligndir. Krukenberg tümörü, gastrik tümörün yumurtalıklara metastazıdır ve tüm over kanserlerinin %1-2sini oluşturur. Son bir haftada epigastrik ağrısı olan 29 yaşında 20.gestasyonel haftasında olan gravida 3, parite 2 bir kadın ünitemize refere edildi. Abdominal ultrasonografide 20 gebelik haftası ile uyumlu biyometrik ölçümleri olan bir bebek izlendi. Ayrıca her iki adneksiyal alana doğru uzanan rahimin arkasında yerleşimli 12,8 x 12 cm çapında solid kitle tespit edildi. Genel anestezi altında orta hat kesisi ile batına girildiğinde haftasıyla uyumlu büyüklükte gebe uterus izlendi. Sağ overden kaynaklanan 12 x 13 cm kitle eksize edildi. Sol overden kaynaklanan 17 x 18 cm kitle eksize edildi. Nihai patoloji sonucu pozitif batıniçi yıkama sıvısı ve her iki overe adenokarsinom metastazı olarak geldi. Üç hafta sonra yapılan gastroskopik biyopsinin patoloji sonucu midenin adenokarsinomu olarak geldi. Hastamız takiplere gelmedi.

References

  • 1. Singhal SR, Nanda S, Chaudhry P, Sen P, Singhal SK. Metastatic bilateral malignant ovarian tumors associated with pregnancy. Taiwan J Obstet Gynecol 2009; 48:167–8. doi:10.1016/S1028-4559(09)60280-1
  • 2. Tamussino K, Scholl W, Reich O, Winter R. Gastric carcinoma presenting as a Krukenberg tumor in the 24th week of gestation. Eur J Obstet Gynecol Reprod Biol 1995;62:251–2. doi: 10.1016/0301-2115(95)02179-B
  • 3. Stojnic J, Stefanovic A, Jeremic K, Kadija S, Jeftovic M, Jeremic J. Krukenberg tumor of gastric origin in pregnancy with dismal outcome. Eur J Gynaecol Oncol 2011;32:356-8.
  • 4. Genç M, Genç B, Solak A, Gür E, Sezgin C. Bilateral Krukenberg tumor in a 16-week pregnant woman. Eur J Gynaecol Oncol 2014;35:95-6.
  • 5. McGill FM, Ritter DB, Rickard CS, et al. Krukenberg tumors: can management be improved? Gynecol Obstet Invest 1999;48:61–5.
  • 6. Antonelli NM, Dotters DJ, Katz VL, Kuller JA. Cancer in pregnancy: a review of the literature. Part I. Obstet Gynecol Surv 1996;51:125–34.
  • 7. Shimizu H, Yamasaki M, Ohama K, Tadaharu N, Tanaka Y. Characteristic ultrasonographic appearance of the Krukenberg tumor. J Clin Ultrasound 1990;18:697–703.
  • 8. Choi BI, Choo IW, Han MC, Kim CW. Sonographic appearance of Krukenberg tumor from gastric carcinoma. Gastrointest Radiol 1988;13:15–8.
  • 9. Megibow AJ, Hulnick DH, Bosniak MA, Balthazar EJ. Ovarian metastases: computed tomographic appearances. Radiology 1985;156:161–4.
  • 10. Papakonstantinou E, Liapis A, Kairi-Vassilatou E, Iavazzo C, Kleanthis CK, Kondi-Pafiti A. Virilizing ovarian Krukenberg tumor in a 27-year-old pregnant woman. A case report and literature review. Eur J Gynaecol Oncol 2011;32:331-3.
  • 11. Sandmeier D, Lobrinus JA, Vial Y, Delaloye JF, Genton CY. Bilateral Krukenberg tumor of the ovary during pregnancy. Eur J Gynaecol Oncol 2000;21: 58–60.
  • 12. Due˜nas-Garcia OF, Diaz-Sotomayor M, Chanana C. Bilateral ovarian Krukenberg tumor in a full-term pregnancy. ISRN Obstet Gynecol 2011;2011:620380. doi:10.5402/2011/620380
There are 12 citations in total.

Details

Primary Language Turkish
Journal Section Case Reports
Authors

Tevfik Yoldemir

Publication Date March 30, 2015
Published in Issue Year 2014 Volume: 27 Issue: 3

Cite

APA Yoldemir, T. (2015). İkinci trimesterde bilateral ovaryen Krukenberg tumörü. Marmara Medical Journal, 27(3), 207-209. https://doi.org/10.5472/MMJ.2014.03283.1
AMA Yoldemir T. İkinci trimesterde bilateral ovaryen Krukenberg tumörü. Marmara Med J. March 2015;27(3):207-209. doi:10.5472/MMJ.2014.03283.1
Chicago Yoldemir, Tevfik. “İkinci Trimesterde Bilateral Ovaryen Krukenberg tumörü”. Marmara Medical Journal 27, no. 3 (March 2015): 207-9. https://doi.org/10.5472/MMJ.2014.03283.1.
EndNote Yoldemir T (March 1, 2015) İkinci trimesterde bilateral ovaryen Krukenberg tumörü. Marmara Medical Journal 27 3 207–209.
IEEE T. Yoldemir, “İkinci trimesterde bilateral ovaryen Krukenberg tumörü”, Marmara Med J, vol. 27, no. 3, pp. 207–209, 2015, doi: 10.5472/MMJ.2014.03283.1.
ISNAD Yoldemir, Tevfik. “İkinci Trimesterde Bilateral Ovaryen Krukenberg tumörü”. Marmara Medical Journal 27/3 (March 2015), 207-209. https://doi.org/10.5472/MMJ.2014.03283.1.
JAMA Yoldemir T. İkinci trimesterde bilateral ovaryen Krukenberg tumörü. Marmara Med J. 2015;27:207–209.
MLA Yoldemir, Tevfik. “İkinci Trimesterde Bilateral Ovaryen Krukenberg tumörü”. Marmara Medical Journal, vol. 27, no. 3, 2015, pp. 207-9, doi:10.5472/MMJ.2014.03283.1.
Vancouver Yoldemir T. İkinci trimesterde bilateral ovaryen Krukenberg tumörü. Marmara Med J. 2015;27(3):207-9.