Year 2015, Volume 28 , Issue 1, Pages 24 - 34 2015-09-30

How to approach castration-resistant prostate cancer?

Sevil BAVBEK [1]

The therapeutic landscape of castration-resistant prostate
cancer (CRPC) has changed dramatically in the last decade.
Previously, limited to castration, second-line hormonal
manipulations, and palliative treatment with mitoxantrone
plus prednisone, median overall survival (OS) remained
in the 9-18 months range. With multiple lines of survival
improving chemotherapies, AR-directed drugs, as well as
new immunotherapy and bone-directed therapies, median
OS increased to more than 30 months and quality of life
increased accordingly. The question remains, as how to
sequence, and choose the best therapeutic option for each
individual patient with the current data.
Keywords: Prostatic neoplasms, Castration-resistant,
Immunotherapy, Chemotherapy, Antineoplastic agents,
Hormonal, Radioimmunotherapy

Prostatic neoplasms, Castration-resistant, median overall survival (OS) remained in the 9-18
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Primary Language en
Journal Section Articles

Author: Sevil BAVBEK


Publication Date : September 30, 2015

Bibtex @ { marumj2880, journal = {Marmara Medical Journal}, issn = {1019-1941}, eissn = {1309-9469}, address = {}, publisher = {Marmara University}, year = {2015}, volume = {28}, pages = {24 - 34}, doi = {10.5472/mmj.80248}, title = {How to approach castration-resistant prostate cancer?}, key = {cite}, author = {Bavbek, Sevil} }
APA Bavbek, S . (2015). How to approach castration-resistant prostate cancer? . Marmara Medical Journal , Special Issue :1 Oncology , 24-34 . DOI: 10.5472/mmj.80248
MLA Bavbek, S . "How to approach castration-resistant prostate cancer?" . Marmara Medical Journal 28 (2015 ): 24-34 <>
Chicago Bavbek, S . "How to approach castration-resistant prostate cancer?". Marmara Medical Journal 28 (2015 ): 24-34
RIS TY - JOUR T1 - How to approach castration-resistant prostate cancer? AU - Sevil Bavbek Y1 - 2015 PY - 2015 N1 - doi: 10.5472/mmj.80248 DO - 10.5472/mmj.80248 T2 - Marmara Medical Journal JF - Journal JO - JOR SP - 24 EP - 34 VL - 28 IS - 1 SN - 1019-1941-1309-9469 M3 - doi: 10.5472/mmj.80248 UR - Y2 - 2021 ER -
EndNote %0 Marmara Medical Journal How to approach castration-resistant prostate cancer? %A Sevil Bavbek %T How to approach castration-resistant prostate cancer? %D 2015 %J Marmara Medical Journal %P 1019-1941-1309-9469 %V 28 %N 1 %R doi: 10.5472/mmj.80248 %U 10.5472/mmj.80248
ISNAD Bavbek, Sevil . "How to approach castration-resistant prostate cancer?". Marmara Medical Journal 28 / 1 (September 2015): 24-34 .
AMA Bavbek S . How to approach castration-resistant prostate cancer?. Marmara Med J. 2015; 28(1): 24-34.
Vancouver Bavbek S . How to approach castration-resistant prostate cancer?. Marmara Medical Journal. 2015; 28(1): 24-34.
IEEE S. Bavbek , "How to approach castration-resistant prostate cancer?", Marmara Medical Journal, vol. 28, no. 1, pp. 24-34, Sep. 2015, doi:10.5472/mmj.80248