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Year 2006, Volume: 19 Issue: 2, 65 - 72, 26.06.2015

Abstract

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References

  • 1. McEwen BS. Stress, adaptation, and disease. Allostasis and allostatic load. Ann NY Acad Sci 1998; 840: 33-44.
  • 2. Collins SM. Stress and the Gastrointestinal Tract. IV. Modulation of intestinal inflammation by stress: basic mechanisms and clinical relevance. Am J Physiol Gastrointest Liver Physiol 2001; 280: G315-G318.
  • 3. Mawdsley JE, Rampton DS. Psychological stress in IBD: new insights into pathogenic and therapeutic implications. Gut. 2005 Oct;54(10):1481-91.
  • 4. Levenstein S, Prantera C, Varvo V, Scribano ML, Andreoli A, Luzi C, Arca M, Berto E, Milite G, Marcheggiano A. Stress and exacerbation in ulcerative colitis: a prospective study of patients enrolled in remission. Am J Gastroenterol. 2000 May;95(5):1213-20.
  • 5. Gue M, Bonbonne C, Fioramonti J, More J, Del Rio-Lacheze C, Comera C, Bueno L. Stressinduced enhancement of colitis in rats: CRF and arginine vasopressin are not involved. Am J Physiol. 1997 Jan;272(1 Pt 1):G84-91.
  • 6. Çakır B , Bozkurt A, Ercan F and Yegen BÇ. The anti-inflammatory effect of leptin on experimental colitis: involvement of endogenous glucocorticoids. Peptides. 2004;Volume 25, Issue 1 , January Pages 95-104.
  • 7. Gulpinar MA, Ozbeyli D, Arbak S, Yegen BC. Anti-inflammatory effect of acute stress on experimental colitis is mediated by cholecystokinin-B receptors. Life Sci. 2004 May 21;75(1):77-91.9.
  • 8. Rosenfeld P, Gutierrez YA, Martin AM, et al. Maternal regulation of the adrenocortical response in preweanling rats. Physiol Behav 1991;50:661– 71.
  • 9. Kuhn CM. and Schanberg SM. Responses to maternal separation: mechanisms and mediators. Int J Dev Neurosci 1998; 16: 261-270.
  • 10. Barreau F, Ferrier L, Fioramonti J and Bueno L. Neonatal maternal deprivation triggers long term alterations in colonic epithelial barrier and mucosal immunity in rats. Gut 2004;53:501-506
  • 11. Ackerman SH, Hofer MA, Weiner H. Early maternal separation increases gastric ulcer risk in rats by producing a latent thermoregulatory disturbance. Science 1978;201:373–6.
  • 12. Milde AM, Enger O, Murison R. The effects of postnatal maternal separation on stress responsivity and experimentally induced colitis in adult rats.Physiol Behav. 2004 Mar;81(1):71-84.
  • 13. Barr AM, Young CE, Sawada K, Trimble WS, Phillips AG, Honer WG, Eur J Neurosci. Abnormalities of presynaptic protein CDCrel-1 in striatum of rats reared in social isolation: relevance to neural connectivity in schizophrenia. 2004 Jul;20(1):303-7.
  • 14. Kresse AE, Million M, Saperas E and Tache Y. Colitis induces CRF expression in hypothalamic magnocellular neurons and blunts CRF gene response to stress in rats. Am. J. Physiol. 2001; 281: pp. G1203–G1213.
  • 15. Macpherson B. and Pfeiffer C. Experimental production of diffuse colitis in rats. Digestion 1978; 17: pp. 135-150.
  • 16. Bradley PP, Priebat DA, Christersen RD and Rothstein G.Measurement of cutaneous inflammation. Estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 1982; 78: pp. 206–209.
  • 17. Beuge JA and Aust SD. Microsomal lipid peroxidation. Methods Enzymol 1978; 52: pp. 302– 311.
  • 18. Sapolsky RM and Meaney MJ, Maturation of the adrenocortical stress response: neuroendocrine control mechanisms and the stress hyporesponsive period. Brain Res. 396 (1986), pp. 64–76.
  • 19. Arborelius L, Owens MJ, Plotsky PM, and Nemeroff CB. The role of corticotropin-releasing factor in depression and anxiety disorders. J Endocrinol 1999; 160: 1-12.
  • 20. Caldji C, Francis D, Sharma S, Plotsky PM, and Meaney MJ. The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and noveltyinduced fearfulness in the rat. Neuropsychopharmacology 2000; 22: 219-229.
  • 21. Heim C, Newport DJ, Heit S, at al. Pituitaryadrenal and autonomic responses to stress in women after sexual and physical abuse in childhood. JAMA 2000; 284: 592-597.
  • 22. Bakshi, VP, and Kalin NH. Corticotropin-releasing hormone and animal models of anxiety: geneenvironment interactions. Biol Psychiatry 48: 1175- 1198, 2000
  • 23. Caldji C, Diorio J, and Meaney MJ. Variations in maternal care in infancy regulate the development of stress reactivity. Biol Psychiatry 48: 1164-1174, 2000
  • 24. Ladd CO, Huot RL, Thrivikraman KV, Nemeroff CB, Meaney MJ, and Plotsky P. Long-term behavioral and neuroendocrine adaptations to adverse early experience. In: The Biological Basis for Mind Body Interactions, edited by Mayer EA, and Saper CB.. Amsterdam: Elsevier, 2000, p. 81- 103.
  • 25. Ackerman SH, Hofer MA, Weiner H. Predisposition to gastric erosions in the rat: behavioral and nutritional effects of early maternal separation. Gastroenterology 1978;75:649–54.
  • 26. Bailey MT, Coe CL. Maternal separation disrupts the integrity of the intestinal microflora in infant rhesus monkeys. Dev Psychobiol 1999;35:146–55.
  • 27. Söderholm JD, Yates DA, Gareau MG, et al. Neonatal maternal separation predisposes adult rats to colonic barrier dysfunction in response to mild stress. Am J Physiol Gastrointest Liver Physiol 2002;283:G1257–63.
  • 28. Meerlo P, Horvath KM, Nagy GM, Bohus B and Koolhaas JM, The influence of postnatal handling on adult neuroendocrine and behavioural stress reactivity. J. Neuroendocrinol. 11 (1999), pp. 925– 933.
  • 29. Meaney MJ, Mitchell JB, Aitken DH, Bhatnagar S, Bodnoff SR, Iny LJ et al., The effects of neonatal handling on the development of the adrenocortical response to stress: implications for neuropathology and cognitive deficits in later life. Psychoneuroendocrinology 16 (1991), pp. 85–103.
  • 30. Jans JE and Woodside BE, Nest temperature: effects on maternal behavior, pup development, and interactions with handling. Dev. Psychobiol. 23 (1990), pp. 519–534.
  • 31. Ross D, Glutathione, free radicals and chemotherapeutic agents, Pharmacol Ther 37 (1988), pp. 231–249.
  • 32. Shaw S, Herbert V, Colman N and Jayatılleke E, Efffect of ethanol-generated free radicals on gastric intrinsic factor and glutathione, Alcohol 7 (1990), pp. 153–157.
  • 33. Weiss SJ, Ward PA. Immune complex-induced generation of oxygen metabolites by human neutrophils. J Immunol 1982; 129, 309-19.
  • 34. Sismonds NJ and Rampton DS, Inflammatory bowel disease: a radical view, Gut 34 (1994), pp. 861–865.
  • 35. Donnahoo KK, Meng X, Ayala A, Cain MP, Harken AH and Meldrum DR, Early kidney TNF-α expression mediates neutrophil infiltration and injury after renal ischemia-reperfusion, Am J Physiol 277 (1999), pp. R922–R929.
  • 36. Thibonnier M, Conarty DM, Preston JA, Plesnicher CL, Dweik RA and Erzurum SC, Human vascular endothelial cells express oxytocin receptors, Endocrinology 140 (1999), pp. 1301–1309.
  • 37. Wang S, Bartolome JV and Schanberg SM, Neonatal deprivation of maternal touch may suppress ornithine decarboxylase via downregulation of the proto-oncogenes c-myc and max. J. Neurosci. 16 (1996), pp. 836–842.
  • 38. Glavin GB, Pare WP. Early weaning predisposes rats to exacerbated activity-stress ulcer formation. Physiol Behav 1985;34:907–9.
  • 39. Gue M, Bonbonne C, Fioramonti J, More J, Del Rio-Lacheze L,Comera C, et al. Stress-induced enhancement of colitis in rats(1992) CRF and arginine vasopressin are not involved. Am J Physiol 1997;272:G84–91.

HAYATIN ERKEN DÖNEMİNDE KARŞILAŞILAN SOSYAL İZOLASYON STRESİ, KOLON İNFLAMASYONUNUN ŞİDDETİNİ AZALTIR

Year 2006, Volume: 19 Issue: 2, 65 - 72, 26.06.2015

Abstract

Amaç: Hayatın erken dönemindeki stresin, ileri yaştaki akut barsak inflamasyonu ve strese maruz kalma
üzerine etkilerini araştırmak.
Material Metod: Dişi Sprague–Dawley sıçanlara, doğum sonrası 21. günde, sosyal izolasyon stresi
uygulandı. 250 g. ağırlığa ulaşılana dek beklendi. 60 günlük protokolün son 3 gününde, izole edilen,
edilmeyen gruplara sudan kaçınma stresi (WAS) 30 dak./gün uygulandı. Sıçanların kalan yarısında ise izole
olan, olmayan gruplara, kolona %5'lik asetik asit verilerek kolit oluşturuldu. Son WAS uygulamasından
hemen sonra ya da kolit indüksiyonunun 4. gününde sıçanlar dekapite edilerek, TNF-alpha seviyelerinin
ölçümü için kan, histolojik değerlendirme, doku myeloperoksidaz (MPO) aktivitesi, nötrofil infiltrasyonunun
göstergesi, ölçümü ve glutatyon (GSH) seviyelerinin, antioksidan, ölçümü için kolon dokusu alındı.
Bulgular: İzole olan, olmayan guruplarda, WAS ve kolit indüksiyonu serum TNF-alpha, doku MDA
seviyelerini, MPO aktivitelerini kontrole göre anlamlı arttırmıştır (p

References

  • 1. McEwen BS. Stress, adaptation, and disease. Allostasis and allostatic load. Ann NY Acad Sci 1998; 840: 33-44.
  • 2. Collins SM. Stress and the Gastrointestinal Tract. IV. Modulation of intestinal inflammation by stress: basic mechanisms and clinical relevance. Am J Physiol Gastrointest Liver Physiol 2001; 280: G315-G318.
  • 3. Mawdsley JE, Rampton DS. Psychological stress in IBD: new insights into pathogenic and therapeutic implications. Gut. 2005 Oct;54(10):1481-91.
  • 4. Levenstein S, Prantera C, Varvo V, Scribano ML, Andreoli A, Luzi C, Arca M, Berto E, Milite G, Marcheggiano A. Stress and exacerbation in ulcerative colitis: a prospective study of patients enrolled in remission. Am J Gastroenterol. 2000 May;95(5):1213-20.
  • 5. Gue M, Bonbonne C, Fioramonti J, More J, Del Rio-Lacheze C, Comera C, Bueno L. Stressinduced enhancement of colitis in rats: CRF and arginine vasopressin are not involved. Am J Physiol. 1997 Jan;272(1 Pt 1):G84-91.
  • 6. Çakır B , Bozkurt A, Ercan F and Yegen BÇ. The anti-inflammatory effect of leptin on experimental colitis: involvement of endogenous glucocorticoids. Peptides. 2004;Volume 25, Issue 1 , January Pages 95-104.
  • 7. Gulpinar MA, Ozbeyli D, Arbak S, Yegen BC. Anti-inflammatory effect of acute stress on experimental colitis is mediated by cholecystokinin-B receptors. Life Sci. 2004 May 21;75(1):77-91.9.
  • 8. Rosenfeld P, Gutierrez YA, Martin AM, et al. Maternal regulation of the adrenocortical response in preweanling rats. Physiol Behav 1991;50:661– 71.
  • 9. Kuhn CM. and Schanberg SM. Responses to maternal separation: mechanisms and mediators. Int J Dev Neurosci 1998; 16: 261-270.
  • 10. Barreau F, Ferrier L, Fioramonti J and Bueno L. Neonatal maternal deprivation triggers long term alterations in colonic epithelial barrier and mucosal immunity in rats. Gut 2004;53:501-506
  • 11. Ackerman SH, Hofer MA, Weiner H. Early maternal separation increases gastric ulcer risk in rats by producing a latent thermoregulatory disturbance. Science 1978;201:373–6.
  • 12. Milde AM, Enger O, Murison R. The effects of postnatal maternal separation on stress responsivity and experimentally induced colitis in adult rats.Physiol Behav. 2004 Mar;81(1):71-84.
  • 13. Barr AM, Young CE, Sawada K, Trimble WS, Phillips AG, Honer WG, Eur J Neurosci. Abnormalities of presynaptic protein CDCrel-1 in striatum of rats reared in social isolation: relevance to neural connectivity in schizophrenia. 2004 Jul;20(1):303-7.
  • 14. Kresse AE, Million M, Saperas E and Tache Y. Colitis induces CRF expression in hypothalamic magnocellular neurons and blunts CRF gene response to stress in rats. Am. J. Physiol. 2001; 281: pp. G1203–G1213.
  • 15. Macpherson B. and Pfeiffer C. Experimental production of diffuse colitis in rats. Digestion 1978; 17: pp. 135-150.
  • 16. Bradley PP, Priebat DA, Christersen RD and Rothstein G.Measurement of cutaneous inflammation. Estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 1982; 78: pp. 206–209.
  • 17. Beuge JA and Aust SD. Microsomal lipid peroxidation. Methods Enzymol 1978; 52: pp. 302– 311.
  • 18. Sapolsky RM and Meaney MJ, Maturation of the adrenocortical stress response: neuroendocrine control mechanisms and the stress hyporesponsive period. Brain Res. 396 (1986), pp. 64–76.
  • 19. Arborelius L, Owens MJ, Plotsky PM, and Nemeroff CB. The role of corticotropin-releasing factor in depression and anxiety disorders. J Endocrinol 1999; 160: 1-12.
  • 20. Caldji C, Francis D, Sharma S, Plotsky PM, and Meaney MJ. The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and noveltyinduced fearfulness in the rat. Neuropsychopharmacology 2000; 22: 219-229.
  • 21. Heim C, Newport DJ, Heit S, at al. Pituitaryadrenal and autonomic responses to stress in women after sexual and physical abuse in childhood. JAMA 2000; 284: 592-597.
  • 22. Bakshi, VP, and Kalin NH. Corticotropin-releasing hormone and animal models of anxiety: geneenvironment interactions. Biol Psychiatry 48: 1175- 1198, 2000
  • 23. Caldji C, Diorio J, and Meaney MJ. Variations in maternal care in infancy regulate the development of stress reactivity. Biol Psychiatry 48: 1164-1174, 2000
  • 24. Ladd CO, Huot RL, Thrivikraman KV, Nemeroff CB, Meaney MJ, and Plotsky P. Long-term behavioral and neuroendocrine adaptations to adverse early experience. In: The Biological Basis for Mind Body Interactions, edited by Mayer EA, and Saper CB.. Amsterdam: Elsevier, 2000, p. 81- 103.
  • 25. Ackerman SH, Hofer MA, Weiner H. Predisposition to gastric erosions in the rat: behavioral and nutritional effects of early maternal separation. Gastroenterology 1978;75:649–54.
  • 26. Bailey MT, Coe CL. Maternal separation disrupts the integrity of the intestinal microflora in infant rhesus monkeys. Dev Psychobiol 1999;35:146–55.
  • 27. Söderholm JD, Yates DA, Gareau MG, et al. Neonatal maternal separation predisposes adult rats to colonic barrier dysfunction in response to mild stress. Am J Physiol Gastrointest Liver Physiol 2002;283:G1257–63.
  • 28. Meerlo P, Horvath KM, Nagy GM, Bohus B and Koolhaas JM, The influence of postnatal handling on adult neuroendocrine and behavioural stress reactivity. J. Neuroendocrinol. 11 (1999), pp. 925– 933.
  • 29. Meaney MJ, Mitchell JB, Aitken DH, Bhatnagar S, Bodnoff SR, Iny LJ et al., The effects of neonatal handling on the development of the adrenocortical response to stress: implications for neuropathology and cognitive deficits in later life. Psychoneuroendocrinology 16 (1991), pp. 85–103.
  • 30. Jans JE and Woodside BE, Nest temperature: effects on maternal behavior, pup development, and interactions with handling. Dev. Psychobiol. 23 (1990), pp. 519–534.
  • 31. Ross D, Glutathione, free radicals and chemotherapeutic agents, Pharmacol Ther 37 (1988), pp. 231–249.
  • 32. Shaw S, Herbert V, Colman N and Jayatılleke E, Efffect of ethanol-generated free radicals on gastric intrinsic factor and glutathione, Alcohol 7 (1990), pp. 153–157.
  • 33. Weiss SJ, Ward PA. Immune complex-induced generation of oxygen metabolites by human neutrophils. J Immunol 1982; 129, 309-19.
  • 34. Sismonds NJ and Rampton DS, Inflammatory bowel disease: a radical view, Gut 34 (1994), pp. 861–865.
  • 35. Donnahoo KK, Meng X, Ayala A, Cain MP, Harken AH and Meldrum DR, Early kidney TNF-α expression mediates neutrophil infiltration and injury after renal ischemia-reperfusion, Am J Physiol 277 (1999), pp. R922–R929.
  • 36. Thibonnier M, Conarty DM, Preston JA, Plesnicher CL, Dweik RA and Erzurum SC, Human vascular endothelial cells express oxytocin receptors, Endocrinology 140 (1999), pp. 1301–1309.
  • 37. Wang S, Bartolome JV and Schanberg SM, Neonatal deprivation of maternal touch may suppress ornithine decarboxylase via downregulation of the proto-oncogenes c-myc and max. J. Neurosci. 16 (1996), pp. 836–842.
  • 38. Glavin GB, Pare WP. Early weaning predisposes rats to exacerbated activity-stress ulcer formation. Physiol Behav 1985;34:907–9.
  • 39. Gue M, Bonbonne C, Fioramonti J, More J, Del Rio-Lacheze L,Comera C, et al. Stress-induced enhancement of colitis in rats(1992) CRF and arginine vasopressin are not involved. Am J Physiol 1997;272:G84–91.
There are 39 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Sevgin İşeri This is me

Fatma Tavsu This is me

Beyhan Sağlam This is me

Feriha Ercan This is me

Nursal Gedik This is me

Berrak C. Yeğen This is me

Publication Date June 26, 2015
Published in Issue Year 2006 Volume: 19 Issue: 2

Cite

APA İşeri, S., Tavsu, F., Sağlam, B., Ercan, F., et al. (2015). HAYATIN ERKEN DÖNEMİNDE KARŞILAŞILAN SOSYAL İZOLASYON STRESİ, KOLON İNFLAMASYONUNUN ŞİDDETİNİ AZALTIR. Marmara Medical Journal, 19(2), 65-72.
AMA İşeri S, Tavsu F, Sağlam B, Ercan F, Gedik N, Yeğen BC. HAYATIN ERKEN DÖNEMİNDE KARŞILAŞILAN SOSYAL İZOLASYON STRESİ, KOLON İNFLAMASYONUNUN ŞİDDETİNİ AZALTIR. Marmara Med J. August 2015;19(2):65-72.
Chicago İşeri, Sevgin, Fatma Tavsu, Beyhan Sağlam, Feriha Ercan, Nursal Gedik, and Berrak C. Yeğen. “HAYATIN ERKEN DÖNEMİNDE KARŞILAŞILAN SOSYAL İZOLASYON STRESİ, KOLON İNFLAMASYONUNUN ŞİDDETİNİ AZALTIR”. Marmara Medical Journal 19, no. 2 (August 2015): 65-72.
EndNote İşeri S, Tavsu F, Sağlam B, Ercan F, Gedik N, Yeğen BC (August 1, 2015) HAYATIN ERKEN DÖNEMİNDE KARŞILAŞILAN SOSYAL İZOLASYON STRESİ, KOLON İNFLAMASYONUNUN ŞİDDETİNİ AZALTIR. Marmara Medical Journal 19 2 65–72.
IEEE S. İşeri, F. Tavsu, B. Sağlam, F. Ercan, N. Gedik, and B. C. Yeğen, “HAYATIN ERKEN DÖNEMİNDE KARŞILAŞILAN SOSYAL İZOLASYON STRESİ, KOLON İNFLAMASYONUNUN ŞİDDETİNİ AZALTIR”, Marmara Med J, vol. 19, no. 2, pp. 65–72, 2015.
ISNAD İşeri, Sevgin et al. “HAYATIN ERKEN DÖNEMİNDE KARŞILAŞILAN SOSYAL İZOLASYON STRESİ, KOLON İNFLAMASYONUNUN ŞİDDETİNİ AZALTIR”. Marmara Medical Journal 19/2 (August 2015), 65-72.
JAMA İşeri S, Tavsu F, Sağlam B, Ercan F, Gedik N, Yeğen BC. HAYATIN ERKEN DÖNEMİNDE KARŞILAŞILAN SOSYAL İZOLASYON STRESİ, KOLON İNFLAMASYONUNUN ŞİDDETİNİ AZALTIR. Marmara Med J. 2015;19:65–72.
MLA İşeri, Sevgin et al. “HAYATIN ERKEN DÖNEMİNDE KARŞILAŞILAN SOSYAL İZOLASYON STRESİ, KOLON İNFLAMASYONUNUN ŞİDDETİNİ AZALTIR”. Marmara Medical Journal, vol. 19, no. 2, 2015, pp. 65-72.
Vancouver İşeri S, Tavsu F, Sağlam B, Ercan F, Gedik N, Yeğen BC. HAYATIN ERKEN DÖNEMİNDE KARŞILAŞILAN SOSYAL İZOLASYON STRESİ, KOLON İNFLAMASYONUNUN ŞİDDETİNİ AZALTIR. Marmara Med J. 2015;19(2):65-72.