Year 2015, Volume 28 , Issue 3, Pages 135 - 141 2015-11-28

The evaluation of aortic elasticity in subclinical hypothyroidism
Subklinik hipotiroidide aort elastisitesinin değerlendirilmesi

Sevil ÖZKAN [1] , Mehmet TARIM [2] , Refik DEMİRTUNÇ [3] , Dursun DUMAN [4]


Objective: In this study we evaluated the elastic properties of
the aorta in patients with subclinical hypothyroidism and their
relation with left ventricular diastolic function by transthoracic
echocardiography.
Patients and Methods: Aortic transthoracic echocardiography
was performed and the aortic elasticity was evaluated using the
following parameters; strain, the beta index and distensibility.
Results: There was significant difference in terms of aortic
strain (5.79% vs. 9.45% p <0.001) and distensibility (4.64 versus
3.02 10-3.cm2. dyn-1. p <0.005) between the control group and
patients with subclinical hypothyroidism group. In the subclinical
hypothyroidism group the average mitral early diastolic velocity
(E). (p <0.05) were significantly lower than the mean mitral
diastolic flow velocity / mitral late diastolic flow velocity (E / A)
(p <0.01) observed in the control group. and higher than the mean
mitral late diastolic flow velocity (A) and isovolumetric relaxation
time (IVRT) (P <0.05) in the control group.
Conclusions: In patients with subclinical hypothyroidism
an increase in the aortic stiffness was observed. The diastolic
dysfunction observed in subclinical hypothyroidism is mainly
responsible for the increase in the aortic stiffness.
Keywords: Aortic stiffness. Subclinical hypothyroidism. Left
ventricular diastolic dysfunction
Amaç: Bu çalışmada. subklinik hipotiroidili hastalarda aortun elastikiyet özellikleri ve bunların sol ventrikül diyastolik fonksiyonu ile ilişkileri transtorasik ekokardiyografik metod ile araştırıldı. Hastalar ve Yöntemler: Transtorasik ekokardiyografi yapılarak aortun elastikiyet parametreleri olarak aortik strain. beta indeksi ve distensibilite indeksine bakıldı. Bulgular: Kontrol grubu ve subklinik hipotiroidili hasta grubu arasında aortik strain (sırasıyla %9.45’e karşı %5.79. p < 0.001) ve distensibilite (4.64’e karşı 3.02 10-3.cm2.dyn-1. p < 0.005) yönünden anlamlı farklar vardı. Subklinik hipotiroidi grubunda mitral erken diyastolik akım hızı (E) ortalaması (p < 0.05). mitral diyastolik akım hızı/ mitral geç diyastolik akım hızı (E/A) (p < 0.01) kontrol grubu ortalamasına göre anlamlı olarak düşük. mitral geç diyastolik akım hızı ortalaması (A) ve izovolümetrik relaksasyon zamanı ( IVRZ) (p < 0.05) kontrol grubu ortalamasına göre yüksek bulundu. Sonuç: Subklinik hipotiroidili hastalarda aortik stiffness’de artış gözlenmektedir. Subklinik hipotiroidili hastalarda gözlenen diyastolik fonksiyon bozukluğundan esas olarak aortik stiffness artışı sorumlu olabilir.
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Primary Language en
Subjects Medicine
Journal Section Articles
Authors

Author: Sevil ÖZKAN

Author: Mehmet TARIM

Author: Refik DEMİRTUNÇ

Author: Dursun DUMAN

Dates

Publication Date : November 28, 2015

Bibtex @research article { marumj3212, journal = {Marmara Medical Journal}, issn = {1019-1941}, eissn = {1309-9469}, address = {}, publisher = {Marmara University}, year = {2015}, volume = {28}, pages = {135 - 141}, doi = {10.5472/MMJoa.2803.03}, title = {The evaluation of aortic elasticity in subclinical hypothyroidism}, key = {cite}, author = {Özkan, Sevil and Tarım, Mehmet and Demi̇rtunç, Refik and Duman, Dursun} }
APA Özkan, S , Tarım, M , Demi̇rtunç, R , Duman, D . (2015). The evaluation of aortic elasticity in subclinical hypothyroidism . Marmara Medical Journal , 28 (3) , 135-141 . DOI: 10.5472/MMJoa.2803.03
MLA Özkan, S , Tarım, M , Demi̇rtunç, R , Duman, D . "The evaluation of aortic elasticity in subclinical hypothyroidism" . Marmara Medical Journal 28 (2015 ): 135-141 <https://dergipark.org.tr/en/pub/marumj/issue/433/3212>
Chicago Özkan, S , Tarım, M , Demi̇rtunç, R , Duman, D . "The evaluation of aortic elasticity in subclinical hypothyroidism". Marmara Medical Journal 28 (2015 ): 135-141
RIS TY - JOUR T1 - The evaluation of aortic elasticity in subclinical hypothyroidism AU - Sevil Özkan , Mehmet Tarım , Refik Demi̇rtunç , Dursun Duman Y1 - 2015 PY - 2015 N1 - doi: 10.5472/MMJoa.2803.03 DO - 10.5472/MMJoa.2803.03 T2 - Marmara Medical Journal JF - Journal JO - JOR SP - 135 EP - 141 VL - 28 IS - 3 SN - 1019-1941-1309-9469 M3 - doi: 10.5472/MMJoa.2803.03 UR - https://doi.org/10.5472/MMJoa.2803.03 Y2 - 2021 ER -
EndNote %0 Marmara Medical Journal The evaluation of aortic elasticity in subclinical hypothyroidism %A Sevil Özkan , Mehmet Tarım , Refik Demi̇rtunç , Dursun Duman %T The evaluation of aortic elasticity in subclinical hypothyroidism %D 2015 %J Marmara Medical Journal %P 1019-1941-1309-9469 %V 28 %N 3 %R doi: 10.5472/MMJoa.2803.03 %U 10.5472/MMJoa.2803.03
ISNAD Özkan, Sevil , Tarım, Mehmet , Demi̇rtunç, Refik , Duman, Dursun . "The evaluation of aortic elasticity in subclinical hypothyroidism". Marmara Medical Journal 28 / 3 (November 2015): 135-141 . https://doi.org/10.5472/MMJoa.2803.03
AMA Özkan S , Tarım M , Demi̇rtunç R , Duman D . The evaluation of aortic elasticity in subclinical hypothyroidism. Marmara Med J. 2015; 28(3): 135-141.
Vancouver Özkan S , Tarım M , Demi̇rtunç R , Duman D . The evaluation of aortic elasticity in subclinical hypothyroidism. Marmara Medical Journal. 2015; 28(3): 135-141.
IEEE S. Özkan , M. Tarım , R. Demi̇rtunç and D. Duman , "The evaluation of aortic elasticity in subclinical hypothyroidism", Marmara Medical Journal, vol. 28, no. 3, pp. 135-141, Nov. 2015, doi:10.5472/MMJoa.2803.03