Anatomy and Activity Studies of Pedicularis condensata

Abstract

The genus Pedicularis comprises with 11 species, 2 of them

are endemic, in Turkey. The Pedicularis species are known as

“sormuk, sorma, sormuk otu”. Its usage is not well known in

folk medicine, though the usage as food because of its nectar is

recorded in East-Anatolia. According to the published studies

on Pedicularis condensata Bieb. till today, it is seen that this

plant takes a place in patent, taken during the hair dye studies.

Additionally, various investigations on the isolation and activity

of Pedicularis (Kesgerotu) species are reported in literature.

According to these, the Pedicularis species contain iridoids

and phenylethanoid compounds as major components. It has

demonstrated that, the iridoids has antioxidant, antimicrobial,

antiinflamatory, immunomodulator activities etc. and the

phenylethanoid compounds show antioxidant, antibacterial,

antiviral as well as antiinflamatory, hepatoprotective activities

etc. In view of the isolation studies, it is possible that Pedicularis

condensata shows some of these activities. The anatomical

and activity studies on this species were not done. In this

paper, an anatomical study and the results of activity tests of

the extracts, which were obtained using various methods

and different solvents, were presented. The antioxidant and

antimicrobial activities, possessed by various extracts (hexane,

dichloromethane, methanol and methanol macerate), which

were prepared from the aerial parts (collected in Trabzon) by

maceration and Soxhlet extraction, were investigated.

Keywords

• Pedicularis condensata,plant anatomy,antimicrobial,antioxidant

Pedicularis condensata Türüne ait Anatomi ve Aktivite Çalışmaları

Abstract

Pedicularis L. cinsi Türkiye’de 2 tanesi endemik olmak üzere

11 tür ile temsil edilmektedir. Ülkemizde sormuk, sorma,

sormuk otu isimleri ile bilinmektedir. Halk arasında kullanımı

pek bilinmemek ile birlikte Doğu Anadolu’da çiçeklerindeki

balözü nedeni ile gıda olarak kullanımı kayıtlıdır. Bugüne

kadar Pedicularis condensata Bieb. türü üzerinde yapılan

çalışmalar incelendiğinde, saç boyası araştırma çalışmaları

sırasında alınan patentlerde yer aldığı görülmektedir. Ayrıca

Pedicularis (Kesgerotu) türleri üzerinde çeşitli izolasyon

ve aktivite çalışmaları literatürde mevcuttur. Bu türlerin

iridoit ve feniletanoit bileşikleri taşıdıkları görülmektedir.

İridoitler antioksidan, antimikrobiyal, antienflamatuvar,

immunomodülatör vb. etki gösterirken feniletanoit

glikozitleri ise hepatoprotektif, antioksidan, antienflamatuvar,

antibakteriyal, antiviral, vb. etkilere sahiptir. Pedicularis

condensata bitkisinin izolasyon çalışmaları göz önüne

alındığında bu etkilerden bazılarını göstermesi mümkündür.

Daha önce bu tür üzerinde anatomi ve aktivite çalışması

yapılmamıştır. Bu çalışma ile türün anatomik özellikleri ve

farklı yöntemler ile farklı çözücüler kullanılarak elde edilmiş

ekstrelerinin aktivite testlerinin sonuçları sunulmuştur.

Trabzon’dan toplanan bitkinin toprak üstü kısımlarından

maserasyon ve Soxhlet cihazında sürekli ekstraksiyon ile elde

edilen çeşitli ekstrelerin (hekzan, diklorometan, metanol

ekstreleri; metanol maseratı) sahip olduğu antioksidan ve

antimikrobiyal aktiviteleri araştırılmıştır.

Keywords

• Pedicularis condensata,bitki anatomisi,antimikrobiyal,antioksidan

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