Study on the Antimicrobial Effects of Novel Thiazole Derivatives

Year 2017, Volume: 21 Issue: 3, 654 - 659, 24.06.2017

Meral Yılmaz Cankılıç , Leyla Yurttaş

https://doi.org/10.12991/marupj.323584

Abstract

In this work, six 2-[(1/4-methylimidazol/triazol/tetrazol-

2/3/5-yl)thio]-N-(4-substituted thiazol-2-yl) acetamide

derivatives (2a-f) were synthesized. The antimicrobial activities

of these substances were examined against some foodborne

Gram positive and Gram negative test bacteria, Candida albicans,

Candida glabrata, Candida krusei, and Candida parapsilosis

yeasts, and some Aspergillus and Penicillium filamentous fungi

species. The substances were shown considerable antimicrobial

effect to tested pathogenic microorganisms.

Keywords

antibacterial, antifungungal, thiazole

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