Analgesic and anti-inflammatory activity of crude leaf and bark extract of Lantana Camara

Year 2017, Volume: 21 Issue: 4, 810 - 817, 01.12.2017

Shripad M Baıragı , İnayat Bashir Pathan Nitin Nema

Abstract

The purpose of present study was to investigate the analgesic and

anti-inflammatory activity of Lantana camara (Verbenaceae)

leaf and bark extract. The methanol extract of Lantana camara

(MELC) was screened for possible analgesic activity by acetic

acid, hot plate and anti-inflammatory activity by carrageenan

and histamine induced paw edema. The result showed that,

MELC (100 mg/kg and 200 mg/kg) leaf and bark possessed

significant (P <0.01 and P <0.05) anti-inflammatory response

and 200 mg/kg dose of MELC leaf and bark showed more

significant (P <0.01) analgesic activity as compared to the 100

mg/kg dose. Preliminary phytochemical screening result shows

the presence of several phytochemicals which may responsible

for its anti-inflammatory and analgesic actions. The results

indicate the MELC showed great potential for analgesic and

anti-inflammatory activity and may be useful for the medical

purpose.

Keywords

Lantana camara, anti-inflammatory activity, analgesic activity

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