Characterization of Sideritis trojana Bornm. essential oil and its antimicrobial activity

Year 2017, Volume: 21 Issue: 4, 860 - 865, 01.12.2017

Hasan Kırmızıbekmez , Nursenem Karaca Betül Demirci Fatih Demirci

Abstract

The components of the essential oil obtained from the dried

aerial parts of Sideritis trojana Bornm. by hydrodistillation was

analyzed both by GC-FID and GC-MS, simultaneously. Overall

57 compounds were identified representing 83.8% of the oil.

The major components of the oil were identified as valeranone

(11.3%), α-bisabolol (10.9%) and β-caryophyllene (8.8%),

respectively. The composition of the oil showed quantitative

chemical variation from previously studied material in terms of

its major components. Moreover, the essential oil was evaluated

for its in vitro antibacterial and anticandidal activities using

a broth microdilution method. A selected panel of standard

strains of Gram (+) and Gram (-) human pathogens as well

as Candida albicans were used in the assay. As a preliminary

result, it was observed that the oil displayed relatively moderate

antibacterial activity against Helicobacter pylori with MIC value

of 250 μg/mL when compared to standard antimicrobials. As

a conclusion, it is worthwhile to evaluate the plant material

against a broader spectrum of activities.

Keywords

Sideritis trojana; Lamiaceae; essential oil; GC-FID and GC-MS; antimicrobial; Helicobacter pylori.

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