Review

Genomic and Transcriptomic Sequencing and Analysis Approaches

Volume: 4 Number: 1 April 20, 2018
Ümmügülsüm Tanman Zıplar *, Demet Cansaran-duman , Mine Türktaş
EN

Genomic and Transcriptomic Sequencing and Analysis Approaches

Abstract

In this review, we explained that genomic and transcriptomic sequences and analysis assays. First of all, we detailed information of genomic and transcriptomic terms and related analyses. Genomics is aimed to elucidate the structural and functional properties of the genomes. Transcriptomics are used to express quantities of transcripts in a physiological state and specific developmental stage. The methods of genomic and transcriptomic analyses imply highly productive sequence analysis or microarray hybridization analysis as well as bioinformatics analyses. The sequencing technologies include set of methods such as preparing template, sequencing, imaging and data analysis. Firstly, the nucleotide information peculiar to DNA and RNA is obtained by means of the chosen technology in accordance with the goal and scope of the study. The obtained sequences are aligned with respect to a familiar reference sequence, or are combined as de novo. Subsequently, it is determined whether the distinct genomic sets are connected with the other genomic sets by overlapping distinct genomic sets, such as aligned sequence readings, gene annotation, EST, genetic polymorphism, and mobile elements. So, the structural variant to which the obtained sequence data are peculiar is determined. Within the scope of the study, giving information about sequencing technologies and the methods of analyses of the obtained sequences is aimed for researchers work on this subject.

Keywords

Genomics,Transcriptomics,Bioinformatics

References

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APA
Tanman Zıplar, Ü., Cansaran-duman, D., & Türktaş, M. (2018). Genomic and Transcriptomic Sequencing and Analysis Approaches. Middle Black Sea Journal of Health Science, 4(1), 34-42. https://doi.org/10.19127/mbsjohs.370490
AMA
1.Tanman Zıplar Ü, Cansaran-duman D, Türktaş M. Genomic and Transcriptomic Sequencing and Analysis Approaches. Mid Blac Sea J Health Sci. 2018;4(1):34-42. doi:10.19127/mbsjohs.370490
Chicago
Tanman Zıplar, Ümmügülsüm, Demet Cansaran-duman, and Mine Türktaş. 2018. “Genomic and Transcriptomic Sequencing and Analysis Approaches”. Middle Black Sea Journal of Health Science 4 (1): 34-42. https://doi.org/10.19127/mbsjohs.370490.
EndNote
Tanman Zıplar Ü, Cansaran-duman D, Türktaş M (April 1, 2018) Genomic and Transcriptomic Sequencing and Analysis Approaches. Middle Black Sea Journal of Health Science 4 1 34–42.
IEEE
[1]Ü. Tanman Zıplar, D. Cansaran-duman, and M. Türktaş, “Genomic and Transcriptomic Sequencing and Analysis Approaches”, Mid Blac Sea J Health Sci, vol. 4, no. 1, pp. 34–42, Apr. 2018, doi: 10.19127/mbsjohs.370490.
ISNAD
Tanman Zıplar, Ümmügülsüm - Cansaran-duman, Demet - Türktaş, Mine. “Genomic and Transcriptomic Sequencing and Analysis Approaches”. Middle Black Sea Journal of Health Science 4/1 (April 1, 2018): 34-42. https://doi.org/10.19127/mbsjohs.370490.
JAMA
1.Tanman Zıplar Ü, Cansaran-duman D, Türktaş M. Genomic and Transcriptomic Sequencing and Analysis Approaches. Mid Blac Sea J Health Sci. 2018;4:34–42.
MLA
Tanman Zıplar, Ümmügülsüm, et al. “Genomic and Transcriptomic Sequencing and Analysis Approaches”. Middle Black Sea Journal of Health Science, vol. 4, no. 1, Apr. 2018, pp. 34-42, doi:10.19127/mbsjohs.370490.
Vancouver
1.Ümmügülsüm Tanman Zıplar, Demet Cansaran-duman, Mine Türktaş. Genomic and Transcriptomic Sequencing and Analysis Approaches. Mid Blac Sea J Health Sci. 2018 Apr. 1;4(1):34-42. doi:10.19127/mbsjohs.370490