Evaluation of Hepatitis B, Hepatitis C and HIV Seropositivity in Chronic Urticaria Patients

Year 2019, , 175 - 179, 31.12.2019

Nihal Altunışık , Sibel Altunışık Toplu , Serpil Şener

https://doi.org/10.19127/mbsjohs.525212

Abstract

Objective: Many factors are responsible for the etiology of chronic urticaria. In
this study, we aimed to determine the relationship between chronic urticaria
and hepatitis B, hepatitis C and human immunodeficiency virus (HIV).

Methods: The study included patients with chronic urticaria who were admitted to
the our dermatology outpatient clinic between July 2018 and January 2019. Hepatitis
B surface antibody (anti-HBs), hepatitis B surface antigen (HBsAg), , hepatitis
C antibody (anti-HCV) and human immunodeficiency virus antibody (anti-HIV) were
recorded retrospectively.

Results: A total of 57 patients were included in the study. Of the 57 patients,
38 (66.7%) were female and 19 (33.3%) were male. The mean age of the patients
was 41.2 ± 13.5 (minimum / maximum: 19-74). In thirty-two patients (56.1%),
anti-HBs positivity was detected and in 25 (43.9%) negative. None of the
patients had HBsAg positivity and HCV antibody positivity. Even though HIV
antibody positivity was detected in one patient, the result of the validation
test was reported as negative.

Conslusion: In our study, no relation was found between chronic urticaria and hepatitis
B, hepatitis C and HIV. However, in patients with chronic urticaria, we think that
there are more cases and multicenter studies to get an idea of whether
screening for hepatitis and HIV should be done routinely.

 

Keywords

Chronic Urticaria, antiHBs, anti-HCV, anti-hıv, HBsAg

References

• Arican O, Kutluk R. Etyopathogenesis in Urticaria. Kartal Education and Research Hospital Medical Journal 2005; 16(1): 46-52.
• Arinkal IZ, Buyuk AY, Sudogan S, Akkiz S, Kavala M. Incidence of Anti HCV Antibody in Chronic Idiopathic Urticaria. Göztepe Medical Journal 2001; 16(1): 14-6.
• Balik D. Hepatit B Epidemiyolojisi. Viral Hepatit 94. Kılıçturgay K editor. İstanbul: Tayf Ofset; 1994. p. 91-102.
• Berg RE, Kantor GR, Bergfeld WF. Urticarial vasculitis. Int J Dermatol 1988; 27:468.
• Bilen N, Apaydin R, Mutlu B, Bayramgurler D, Yildirim G. Should Hepatitis C Virus Infection Be Investigated in the Cases of Choronic Urticaria? T Clin Dermatology 1999; 9(3): 134-136.
• Cakaloglu Y. Hepatitis C virus infection. Epidemiology, pathogenesis, clinical, treatment. Viral Hepatit 94. Kılıcturgay K, editor. Istanbul: Tayf Ofset; 1994. p. 191-235.
• Dervis E, Sonmezoglu M, Varnalı E, Ersoy L, Karaoglu A. Prevalence of Hepatitis B Virus Infection in Patients with Urticaria. Viral Hepat J 2001 ;7(1): 1-4.
• Dilek N, Saral Y. Skin Manifestations of HIV Infection. Turkiye Klinikleri J Dermatol-Special Topics 2014; 7(1): 15-26.
• Erel A, Oruk S, Senol E, Gurer MA. Seroprevelance of Hepatitis B Virus and Hepatitis C Virus in Chronic Urticaria. T Clin Dermatology 1999 ;10(1): 13-15.
• Friedman D, Picard-Dahan C, Grossin M, Belaich S. Chronic urticaria revealing an HIV infection. Eur J Dermatol 1995; 5:40
• Gul U, Cevik MA. Hepatitis A, B, C Virus Seroprevalence in Chronic Urticaria. Journal of Internal Medicine 1998; 5(6): 385-7.
• Gungor HK, Akyol A. Pathogenesis of Chronic Urticaria. Turk J Dermatol 2014;4:223-6.
• Iemoli E, Niero F, Borgonovo L, Cossu MV, Piconi S. Successful Omalizumab treatment in HIV positive patient with chronic spontaneous urticaria: a case report. Eur Ann Allergy Clin Immunol. 2017 ;49(2): 88-91.
• Inci A, Gunaydın A. Evaluation of Hepatitis B and Hepatitis C Frequency in Patients with Chronic Urticaria. İKSST Journal 2015; 7(1): 13-16.doi:10.5222/iksst.2015.013.
• Jerry D Brewer, MD, MS, FAADMark DP Davis, MD, FAA. Urticarial vasculitis. Black AK. Urticarial vasculitis. Clin Dermatol 1999; 17:565.
• Jones RR, Bhogal B, Dash A, Schifferli J. Urticaria and vasculitis: a continuum of histological and immunopathological changes. Br J Dermatol 1983; 108:695.
• Kanazawa K, Yaoita H, Tsuda F, Okamoto H. Hepatitis C virus infection in patients with urticaria. J Am Acad Dermatol 1996; 35(2): 195-8.
• Kaya TI, Akyol A. Pathogenesis of urticaria: Recent Advances in the Subject of Chronic Idiopathic Urticaria Pathogenesis. Turkiye Klinikleri J Dermatol 1999; 9(1): 41-50.
• Kose S, Senger SS, Cavdar G. Focal Infections Accompanying Urticaria, a Common Skin Disease. Klimik Journal 2011; 24(2): 98-100.doi:10.5152/kd.2011.23.
• Ozdemir PG, Yazıcıoğlu M. Choronic Urticaria: Etiology and Pathogenesis: Review. Türkiye Klinikleri J Pediatr 2012;21(1):21-6.
• Oztas P, Polat M, Yalcin B, Gur G, Tamer E, Alli N. Hepatitis C Virus-Associated Cutaneous Disorders: Differantial Diagnosis. Turkiye Klinikleri J Med Sci 2007, 27(1):136-138.
• Sarac G, Mantar I, Sener S, Cenk H, Kapicioglu Y. Assessment of change in neutrophil-lymphocyte ratio, platelet-lymphocyteratio in patients with acute and chronic urticaria. 2018;25(4)719-22. DOI: 10.5455/annalsmedres.2018.07.132.