Investigation of Hemogram, Endoscopy, Demographic Properties of Patients Applied by Fecal Occult Blood Test Screening

Year 2019, , 180 - 185, 31.12.2019

Özlem Özdemir , Çağrı Akalın , Hamza Çınar

https://doi.org/10.19127/mbsjohs.531631

Abstract

Objective: Colorectal cancer (CRC) is one of the most common
cancers in the world. Fecal occult blood test (FOBT) is easy and commonly used
test to its screening. The aim of this study was to investigate the demographic
characteristics, hemogram results and endoscopy and outcome status of the
patients who underwent FOBT on history and clinical suspicion and to contribute
to the literature.

Methods: 400 patients who were admitted to the general
surgery polyclinic between 01/12/2016 and 12/12/2017 in Ordu University Medical
Faculty Training and Research Hospital were evaluated retrospectively. The data
of 349 patients who underwent FOBT was reached. Age and sex, hemoglobin,
hematocrit, ferritin levels, upper and lower gastrointestinal endoscopy results
and pathology results of endoscopic biopsies were recorded.

Results: 38 (10.9%) with FOBT (+) and 311 (89.1%) with FOBT
(-) of 349 patients were detected. There was no statistically significant
difference between the two groups in terms of the average age (p = 0.27) and
gender (p = 0.26). There was a significant difference between the two groups in
terms of the rate of upper gastrointestinal endoscopy (p = 0.03). There was a
significant difference between the two groups in terms of the rate of
colonoscopy (p = 0.001). Malignancy was detected in 22,2% of FOBT (+) and in
1,63% of FOBT (-) group by colonoscopy. There was a statistically significant
difference between the two groups in terms of disease diagnoses (p = 0.001).
There was no statistically significant difference between the two groups in
terms of Helicobacter Pylori (H. pylori) (p = 0.31) and intestinal metaplasia (p = 0.44). There was a statistically
significant difference between the two groups in terms of Hb and Htc value (p=
0.05).

Conclusion: According to the results of FOBT, the application
of endoscopy to the patients who are required, provide to detect the
precancerous lesions as well as the malignancies of the upper and lower
gastrointestinal tract. Good knowledge of the importance of this test will
allow early detection of malignancy.

Keywords

Fecal occult blood test, Colorectal cancer, Endoscopy

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