The Efficacy of Tc-99m DMSA Scintigraphy in Children with Vesicoureteral Reflux Accompanying Frequent Urinary Tract Infection

Year 2019, , 252 - 257, 31.12.2019

Mehmet Emin Çelikkaya , Ahmet Atıcı Hasan İkbal Atılgan

https://doi.org/10.19127/mbsjohs.616799

Abstract

Objective:
Urinary tract infection is one of the most common diseases in childhood.
Experimental studies have shown that renal damage due to urinary tract
infection can be prevented by early diagnosis and treatment. The aim of this
study was to evaluate the correlation between vesicoureteral reflux grade and
Technetium-99m- dimercaptosuccinic acid scintigraphy in patients with frequent
urinary tract infection

Methods
Between January and October 2017, 34 cases were
diagnosed as vescoureteral reflux with voiding cystoureterography were
retrospectively evaluated with Technetium-99m- dimercaptosuccinic acid
scintigraphy in terms of renal scar and function. Scars and function ratios
were evaluated in Technetium-99m- dimercaptosuccinic acid scintigraphy
according to voiding cystourethrography grades and correlation between the vesicoureteral
reflux grade and Technetium-99m- dimercaptosuccinic acid scintigraphy findings
were investigated.

Results:
Of 34 patients, 26 (76.5%) were female and 8 (23.5%) were
male. The mean age of the patients was 6.08 ± 4.03 (min: 1 month, max: 17 years).
Twenty-one patients had unilateral vesicoureteral reflux and 13 patients had
bilateral vesicoureteral reflux. Vesicoureteral reflux were detected in 47 of
the total 68 kidneys.

Conclusion:
In children with vesicoureteral reflux, Technetium-99m-
dimercaptosuccinic acid scintigraphy provides useful information to show the
kidney damage and as the vesicoureteral reflux grade increases, the rate of
kidney damage increases. Even in the case of grade 1 and grade 2 vesicoureteral
reflux, which are not expected to cause renal parenchymal damage.
Technetium-99m- dimercaptosuccinic acid scintigraphy is the most successful
imaging method for detecting parenchymal injury.

Keywords

DMSA, Vesicoureteral Reflux, Voiding Cystoureterography

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