Research Article
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Investigation of the Effects of Sun-Dried Apricot with Different Sulfur Levels on Oxidative Stress Markers

Year 2019, , 239 - 245, 31.12.2019
https://doi.org/10.19127/mbsjohs.654240

Abstract

Objective:
Apricots are mostly consumed in dried form worldwide. Studies are reporting
some allergic effects of dried apricot because of its content of sulfur, which
is used in the drying process. Therefore sulphur content has been limited by
many countries. This study was conducted to determine the effects of sun-dried
apricots with different sulfur contents on nitric oxide (NO), malondialdehyde
(MDA) and glutathione (GSH) that are among the markers of oxidative stress.



Methods:
A total of 84 Wistar albino rats were divided into groups as control, sun-dried
apricot, 1000, 2000, 3000 and 4000 ppm sulfured groups. At the end of the 12th
week, rats were sacrificed under general anesthesia. NO, MDA and GSH levels
were studied at the end of the experiment from the ovarian and testicular
tissues of the rats.



Results:
No statistically significant differences were found among the groups in terms
of NO, MDA and GSH in the ovarian and testicular tissues removed from the rats



Conclusion:
We claim that sulfur amount of dried apricots is not
affect on reproductive system. This study is guiding further studies that will
be conducted against the restrictions in sulfur used in the drying process of
dried apricots, which is economically very important for dried fruits sector.

References

  • Asma BM. Malatya: World’s capital of apricot culture. Chronica Horticulturae. 2007; 47: 20–4.
  • Bayram MA, Kan T, Birhanlı O. Characterization of Promising Apricot (Prunus armeniaca L.) Genetic Resources in Malatya. Genetic Resources and Crop Evolution. 2007; 54: 205–12.
  • Chan YH, Lau KK, Yiu KH, Li SW, Chan HT, Fong DY, Tam S, Lau CP, Tse HF. Reduction of C-reactive protein with isoflavone supplement reverses endothelial dysfunction in patients with ischaemic stroke. European Heart Journal. 2008; 29: 2800–7.
  • Codex Alimentarius International Food Standards. Codex Standard for Dried Apricots. Codex Stan. (serial online) 1981; 130: 1-5. Available from: URL: http:/www.fao.org/fao-who-codexalimentarius/codex-texts/all-standards/en/.
  • Cortas NK, Wakid NW. Determination of inorganic nitrate in serum and urine by a kinetic cadmium reduction method. Clinical Chemistry. 1990; 36: 1440-3.
  • Davis EG, McBean DMG, Roonele ML, Gipps PG. Mechanisms of sulphur dioxide loss from dried fruits in flexible films. International Journal of Food Science and Technology. 1973; 8: 391-405. Ishiwata H, Nishijima M, Fukasawa Y, Ito Y, Yamada T. Evaluation of the inorganic food additive (nitrite, nitrate and sulfur dioxide) content of foods and estimation of daily intake based on the results of official inspection in Japan in Fiscal Year 1994. J. Food Hygiene and Safety Science.1998; 39: 78-88.
  • Jayaraman KS, Das Gupta DK. Dehydration of fruits and vegetables-Recent developments in principles and techniques. Drying Technology: An International Journal. 1992; 10: 1-50.
  • Knorst MM, Kienast K, Quernheim JM, Ferlinz R. Effect of Sulfur Dioxide on Cytokine Production of Human Alveolar Macrophages in Vitro. Archives of Environmental Health: An International Journal. 1996; 51(2): 150-156.
  • Koksal N, Hasanoglu HC, Gokirmak M, Yildirim Z, Gultek A. Apricot Sulfurization: An Occupation That Induces an Asthma-Like Syndrome in Agricultural Environments. American Journal of Industrial Medicine. 2003; 43: 447–53.
  • Koksal N, Yıldırım Z, Gokırmak M, Hasanoğlu HC, Mehmet N, Avcı H. The role of nitric oxide and cytokines in asthma-like syndrome induced by sulfur dioxide exposure in agricultural environment. Clinica Chimica Acta. 2003a; 336: 115–22.
  • Lizada MCC, Yang SF. Sulfite-lnduced Lipid Peroxidation. Lipids. 1981; 16: 189-94.
  • McBean, DMcG. Levels of free and combined sulfur dioxide in fruits during sulfuring and drying. Food Technology. 1967; 21 (10): 112-6.
  • Meng Z, Liu Y. Cell morphological ultrastructural changes in various organs from mice exposed by inhalation to sulfur dioxide. Inhalation Toxicology. 2007; 19: 543-51.
  • Mihara M, Uchiyama M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Analytical Biochemistry. 1978; 86: 271–8.
  • Miranda G, Berna A, Salazar D, Mulet A. Sulphur dioxide evolution during apricot storage. Food Science and Technology. 2009; 42: 531-3.
  • Parlakpinar H, Olmez E, Acet A, Ozturk F, Tasdemir S, Ates B, et al. Beneficial effects of apricot-feeding on myocardial ischemia-reperfusion injury in rats. Food and Chemical Toxicology. 2009; 47: 802-8.
  • Raj V, Mishra AK, Mishra A, Najam AK. Hepatoprotective effect of Prunus armeniaca L. (Apricot) leaf extracts on Paracetamol induced liver damage in Wistar rats. Pharmacognosy Journal. 2016; 8: 154-8.
  • Ruiz D, Egea J, Gil MI, Tomás-Barberán FA. Characterization and quantitation of phenolic compounds in new apricot (Prunus armeniaca L.) varieties. Journal of Agricultural Food Chemistry. 2005; 53: 9544-52.
  • Shapiro R. Genetic effects of Bisulfite (Sulfur dioxide). Mutation Research.1977; 39: 149-76.
  • Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem. 1969; 27: 502-22.
  • Turkyılmaz M, Tagi S, Ozkan M. Changes in chemical and microbial qualities of dried apricots containing sulphur dioxide at different levels during storage. Food and Bioprocess Technology. 2013; 6: 1526-38.
  • Türkiye Cumhuriyeti Ekonomi Bakanlığı (TCEB). Sektör Raporları, Kuru Kayısı. 2017; 1-3. Available from: URL: https:/www.ticaret.gov.tr/data/5b8700a513b8761450e18d81/Kuru_Kayisi.pdf.
  • Yılmaz I, Cetin A, Bilgic Y. Hepatoprotective Effects of Apricot against Acetaminophen-Induced Acute Hepatotoxicity in Rats. American Journal of Pharmacological Sciences. 2015; 3(2): 44-8.
  • Zamboni CB, Medeiros IMMA, Medeiros JAG. Analysis of sulphur in dried fruits using NAA. International Nuclear Atlantic Conference – (INAC); October 24-28; Belo Horizonte, Brazil: p. 1-6. 2011.
Year 2019, , 239 - 245, 31.12.2019
https://doi.org/10.19127/mbsjohs.654240

Abstract

References

  • Asma BM. Malatya: World’s capital of apricot culture. Chronica Horticulturae. 2007; 47: 20–4.
  • Bayram MA, Kan T, Birhanlı O. Characterization of Promising Apricot (Prunus armeniaca L.) Genetic Resources in Malatya. Genetic Resources and Crop Evolution. 2007; 54: 205–12.
  • Chan YH, Lau KK, Yiu KH, Li SW, Chan HT, Fong DY, Tam S, Lau CP, Tse HF. Reduction of C-reactive protein with isoflavone supplement reverses endothelial dysfunction in patients with ischaemic stroke. European Heart Journal. 2008; 29: 2800–7.
  • Codex Alimentarius International Food Standards. Codex Standard for Dried Apricots. Codex Stan. (serial online) 1981; 130: 1-5. Available from: URL: http:/www.fao.org/fao-who-codexalimentarius/codex-texts/all-standards/en/.
  • Cortas NK, Wakid NW. Determination of inorganic nitrate in serum and urine by a kinetic cadmium reduction method. Clinical Chemistry. 1990; 36: 1440-3.
  • Davis EG, McBean DMG, Roonele ML, Gipps PG. Mechanisms of sulphur dioxide loss from dried fruits in flexible films. International Journal of Food Science and Technology. 1973; 8: 391-405. Ishiwata H, Nishijima M, Fukasawa Y, Ito Y, Yamada T. Evaluation of the inorganic food additive (nitrite, nitrate and sulfur dioxide) content of foods and estimation of daily intake based on the results of official inspection in Japan in Fiscal Year 1994. J. Food Hygiene and Safety Science.1998; 39: 78-88.
  • Jayaraman KS, Das Gupta DK. Dehydration of fruits and vegetables-Recent developments in principles and techniques. Drying Technology: An International Journal. 1992; 10: 1-50.
  • Knorst MM, Kienast K, Quernheim JM, Ferlinz R. Effect of Sulfur Dioxide on Cytokine Production of Human Alveolar Macrophages in Vitro. Archives of Environmental Health: An International Journal. 1996; 51(2): 150-156.
  • Koksal N, Hasanoglu HC, Gokirmak M, Yildirim Z, Gultek A. Apricot Sulfurization: An Occupation That Induces an Asthma-Like Syndrome in Agricultural Environments. American Journal of Industrial Medicine. 2003; 43: 447–53.
  • Koksal N, Yıldırım Z, Gokırmak M, Hasanoğlu HC, Mehmet N, Avcı H. The role of nitric oxide and cytokines in asthma-like syndrome induced by sulfur dioxide exposure in agricultural environment. Clinica Chimica Acta. 2003a; 336: 115–22.
  • Lizada MCC, Yang SF. Sulfite-lnduced Lipid Peroxidation. Lipids. 1981; 16: 189-94.
  • McBean, DMcG. Levels of free and combined sulfur dioxide in fruits during sulfuring and drying. Food Technology. 1967; 21 (10): 112-6.
  • Meng Z, Liu Y. Cell morphological ultrastructural changes in various organs from mice exposed by inhalation to sulfur dioxide. Inhalation Toxicology. 2007; 19: 543-51.
  • Mihara M, Uchiyama M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Analytical Biochemistry. 1978; 86: 271–8.
  • Miranda G, Berna A, Salazar D, Mulet A. Sulphur dioxide evolution during apricot storage. Food Science and Technology. 2009; 42: 531-3.
  • Parlakpinar H, Olmez E, Acet A, Ozturk F, Tasdemir S, Ates B, et al. Beneficial effects of apricot-feeding on myocardial ischemia-reperfusion injury in rats. Food and Chemical Toxicology. 2009; 47: 802-8.
  • Raj V, Mishra AK, Mishra A, Najam AK. Hepatoprotective effect of Prunus armeniaca L. (Apricot) leaf extracts on Paracetamol induced liver damage in Wistar rats. Pharmacognosy Journal. 2016; 8: 154-8.
  • Ruiz D, Egea J, Gil MI, Tomás-Barberán FA. Characterization and quantitation of phenolic compounds in new apricot (Prunus armeniaca L.) varieties. Journal of Agricultural Food Chemistry. 2005; 53: 9544-52.
  • Shapiro R. Genetic effects of Bisulfite (Sulfur dioxide). Mutation Research.1977; 39: 149-76.
  • Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem. 1969; 27: 502-22.
  • Turkyılmaz M, Tagi S, Ozkan M. Changes in chemical and microbial qualities of dried apricots containing sulphur dioxide at different levels during storage. Food and Bioprocess Technology. 2013; 6: 1526-38.
  • Türkiye Cumhuriyeti Ekonomi Bakanlığı (TCEB). Sektör Raporları, Kuru Kayısı. 2017; 1-3. Available from: URL: https:/www.ticaret.gov.tr/data/5b8700a513b8761450e18d81/Kuru_Kayisi.pdf.
  • Yılmaz I, Cetin A, Bilgic Y. Hepatoprotective Effects of Apricot against Acetaminophen-Induced Acute Hepatotoxicity in Rats. American Journal of Pharmacological Sciences. 2015; 3(2): 44-8.
  • Zamboni CB, Medeiros IMMA, Medeiros JAG. Analysis of sulphur in dried fruits using NAA. International Nuclear Atlantic Conference – (INAC); October 24-28; Belo Horizonte, Brazil: p. 1-6. 2011.
There are 24 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Research articles
Authors

Tuğba Raika Kıran

Onder Otlu 0000-0001-5958-7609

Ercan Karabulut 0000-0001-6733-2497

Nermin Ozcan 0000-0001-5327-9090

Publication Date December 31, 2019
Published in Issue Year 2019

Cite

Vancouver Kıran TR, Otlu O, Karabulut E, Ozcan N. Investigation of the Effects of Sun-Dried Apricot with Different Sulfur Levels on Oxidative Stress Markers. Mid Blac Sea J Health Sci. 2019;5(3):239-45.

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