Quality of Life, Emotional and Behavioral problems in Full-Term Small for Gestational Age Infants at Preschool Age

Year 2021, Volume: 7 Issue: 2, 236 - 244, 31.08.2021

Yağmur Gündüz , Kıymet Çelik , Özgür Demirtaş , Nilüfer Okur , Gözde Yazkan

https://doi.org/10.19127/mbsjohs.898300

Abstract

Objective: To determine the emotional, behavioral, and developmental problems and quality of life of children born as Term Small for Gestational Age (SGA) in the preschool period, and to compare them with children born as term appropiate for gestational age (AGA).

Method: This study conducted as a prospective case control study. Term SGA babies who were followed up in the Neonatal Intensive Care Unit were taken in the study group, while babies born with term AGA were taken in the control group. All participants’ parents filled the Sociodemographic form, Child Behavior Checklist (CBCL) and Pediatric Quality of Life Scale (PedsQL) and were asked questions to complete the ADSI by expert psychologists.

Results: 20 SGA (63 months ± 7 months) born term and 20 AGA (59 months ± 8 months) born term children were taken in the study group. There was no significant difference between the groups in terms of gestational age, gender, and age at the outpatient clinic. Social problems were significantly higher in the SGA group (p = 0.014). The school functionality score (SchFS) was found to be significantly lower in the SGA group (p <0.01). In the developmental evaluation, there was no statistically significant difference between the two groups.

Conclusion: The long-term follow-up of term SGA patients is important, as inadequate recognition or inadequate treatment of the disorders that may arise may cause impairment not only in the quality of life and psychiatric condutions of the patients, but also in their ability to adapt to the society.Key words: Chondroblastoma, lower extremity, pain.

Keywords

SGA, emotional, behavioral, developmental, quality of life

References

• 1. Maulik D. Fetal growth compromise: definitions, standards, and classification. Clin Obstet Gynecol. 2006; 49: 214–218.
• 2. Arcangeli T, Thilaganathan B, Hooper R, Khan KS, Bhide A. Neurodevelopmental delay in small babies at term: a systematic review. Ultrasound in obstetrics & gynecology. 2012; 40(3), 267-275.
• 3. Leitner Y, Fattal-Valevski A, Geva R, Eshel R, et al. Neurodevelopmental outcome of children with intrauterine growth retardation: A longitudinal, 10-year prospective study. J Child Neurol. 2007; 22: 580-587.
• 4. McCormick MC, Workman-Daniels K, Brooks-Gunn J. The behavioral and emotional well-being of school-age children with different birth weights. Pediatrics. 1996; 97: 18–25.
• 5. Savchev S, Sanz‐Cortes M, Cruz‐Martinez R, Arranz A, Botet F, Gratacos E, et al. Neurodevelopmental outcome of full‐term small‐for‐gestational‐age infants with normal placental function. Ultrasound in obstetrics & gynecology. 2013; 42(2), 201-206.
• 6. Parra-Saavedra M, Crovetto F, Triunfo S, Savchev S, Peguero A, Nadal A, et al. Neurodevelopmental outcomes of near-term small-for-gestational-age infants with and without signs of placental underperfusion. Placenta. 2014; 35(4), 269-274.
• 7. Hall J, Wolke D. A comparison of prematurity and small for gestational age as risk factors for age 6–13-year emotional problems. Early human development. 2012; 88(10), 797-804.
• 8. Tanis JC, Van Braeckel KN, Kerstjens JM, Bocca-Tjeertes IF, Reijneveld SA, Bos AF. Functional outcomes at age 7 years of moderate preterm and full term children born small for gestational age. The Journal of pediatrics. 2015; 166(3), 552-558.
• 9. Sommerfelt K, Andersson HW, Sonnander K, Ahlsten G, Ellertsen B, Markestad T, et al. Behavior in term, small for gestational age preschoolers. Early Human Development. 2001; 65(2), 107-121.
• 10. Cornforth CM, Thompson JM, Robinson E, Waldie KE, Pryor JE, Clark P, et al. Children born small for gestational age are not at special risk for preschool emotion and behaviour problems. Early human development. 2012; 88(7), 479-485.
• 11. Klarić AŠ, Kolundžić Z, Galić S, Bošnjak VM, et al. Language development in preschool children born after asymmetrical intrauterine growth retardation. European journal of paediatric neurology. 2012; 16(2), 132-137. 12. Takeuchi A, Yorifuji T, Takahashi K, Nakamura M, Kageyama M, Kubo T, et al. Neurodevelopment in full-term small for gestational age infants: A nationwide Japanese population-based study. Brain and Development. 2016; 38(6), 529-537.
• 13. Varni JW, Seid M, Rode CA. The PedsQL™: measurement model for the pediatric quality of life inventory. Medical care. 1999; 126-139.
• 14. Varni JW, Seid M, Kurtin PS. PedsQL™ 4.0: Reliability and validity of the Pediatric Quality of Life Inventory™ Version 4.0 Generic Core Scales in healthy and patient populations. Medical care. 2001; 800-812.
• 15. Varni JW, Limbers CA, Burwinkle TM. Parent proxy-report of their children's health-related quality of life: an analysis of 13,878 parents' reliability and validity across age subgroups using the PedsQL™ 4.0 Generic Core Scales. Health and quality of life outcomes. 2007; 5(1), 1-10.
• 16. Rautava L, Häkkinen U, Korvenranta E, Andersson S, Gissler M, Hallman M, et al. Health-related quality of life in 5-year-old very low birth weight infants. The Journal of pediatrics. 2009; 155(3), 338-343.
• 17. Fenton TR, Kim JH. A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants. BMC pediatrics. 2013; 13(1), 1-13.
• 18. Achenbach TM, Edelbrock CS. Manual for the Child Behavior Checklist and Revised Child Behavior Profile. Burlington, VT: University of Vermont, Department of Psychiatry; 1983. P. 85-121.
• 19. Erol N, Aslan L, Akçakin M. The adaptation and standardisation of the child behavior checklist among 6–18-year-old Turkish children. In: Sergeant J (ed.) Eunethydis Europan Approaches to Hyperkinetic Disorders. Fotorotor Egg, Zurich, 1995; 109–13.
• 20. Uneri OS, Agaoglu B, Coskun A, Memik NC. Validity and reliability of Pediatric Quality of Life Inventory for 2-to 4-year-old and 5-to 7-year-old Turkish children. Quality of Life Research. 2008; 17(2), 307-315.
• 21. Savaşır N, Sezgin N, Erol N. Ankara Gelişim Tarama Envanteri El Kitabı (Genişletilmiş 3. Basım). Ankara: Rekmay, 2005;17.
• 22. Shah P, Kingdom J. Long-term neurocognitive outcomes of SGA/IUGR infants. Obstetrics, Gynaecology & Reproductive Medicine. 2011; 21(5), 142-146. 23. Van Lieshout RJ, Boyle MH. Canadian youth born large or small for gestational age and externalizing and internalizing problems. The Canadian Journal of Psychiatry. 2011; 56(4), 227-234.
• 24. Zubrick SR, Kurinczuk JJ, McDermott BM, McKelvey RS, Silburn SR, Davies LC. Fetal growth and subsequent mental health problems in children aged 4 to 13 years. Developmental Medicine & Child Neurology. 2000; 42(1), 14-20.
• 25. Indredavik MS, Vik T, Heyerdahl S, Kulseng S, Brubakk AM, et al. Psychiatric symptoms in low-birth-weight adolescents, assessed by screening questionnaires. European child & adolescent psychiatry. 2005; 14(4), 226-236.
• 26. Yang S, Fombonne E, Kramer MS. Duration of gestation, size at birth and later childhood behaviour. Paediatric and perinatal epidemiology. 2011; 25(4), 377-387.
• 27. Sacchi C, Marino C, Nosarti C, Vieno A, Visentin S, Simonelli A, et al. Association of Intrauterine Growth Restriction and Small for Gestational Age Status with Childhood Cognitive Outcomes: A Systematic Review and Meta-analysis. JAMA pediatrics. 2020; 174(8), 772-781.
• 28. Dinesen SJ, Greisen G. Quality of life in young adults with very low birth weight. Archives of Disease in Childhood-Fetal and Neonatal Edition. 2001; 85(3), F165-F169.
• 29. Zwicker JG, Harris SR. Quality of life of formerly preterm and very low birth weight infants from preschool age to adulthood: a systematic review. Pediatrics. 2008; 121(2), e366-e376.
• 30. Larroque B, Bertrais S, Czernichow P, Léger J, et al. School difficulties in 20-year-olds who were born small for gestational age at term in a regional cohort study. Pediatrics. 2001; 108(1), 111-115.