Is Neurogenous Hyperplasia A Cause of Appendiceal Obliteration ? (A retrospective study of 1397 cases)

Year 2001, Volume: 2 Issue: 2, 15 - 17, 01.08.2001

Gülden Diniz Melek Üstün Gülden Çengel Mine Tunakan

Abstract

Aim: In this study the presence of neural tissue components was investigated in appendectomy specimens with an obliterated appendix. Relationship of the neural tissue presence with other appendical lesions such as carcinoid tumors and acute appendicitis was also evaluated. Material and method: Retrospective analysis of 1379 consecutive routine appendectomy specimens revealed 66 cases as "obliterated appendix" (an incidence of 4,2%). Only 38 appropriate cases have been included in this study. Results: By light microscopy, obliteration was located centrally in the appendix without nodule formation. Loose proliferation of spindle cells, usually in a myxoid background, and with entrapped fat tissue was frequently observed. The spindle cells were positive for S-100 protein in 18 of 38 cases (47,3 %). Conclusion: We emphasise that neurogenous hyperplasia in obliterated appendices is a rather common entity, andthatmost cases ofso-calledfibrous obliteration actuallyrepresentneurogenicappendicopathy.

Keywords

obliterated appendix, fibrous obliteration, neurogenous hyperplasia

NÖROJENİK HİPERPLAZİ APPENDİKS OBLİTERASYONU NEDENİ MİDİR ? ( 1397 olgunun retrospektif incelemesi )

Abstract

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Keywords

oblitere appendiks, fibröz obliterasyon, nöral hiperplazi

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