HİPOTANSİYONUN YOL AÇTIĞI BİR İSKEMİK HEPATİT OLGUSU

Year 2001, Volume: 2 Issue: 3, 27 - 30, 01.12.2001

Harun Akar Taşkın Şentürk Vahit Yükselen Çiğdem Özbaşlı Leyi Nil Çulhacı Gürhan Kadıköylü İrfan Yavaşoğlu

Abstract

İskemik hepatit, karaciğerde dolaşım yetmezliği sonucu, 24 saat içinde serum transaminaz ve laktik dehidrogenaz seviyelerinin normale göre 75-100 katı kadar yükselip, 7-10 gün içinde tekrar normale dönmesi ile karakterize klinik bir tablodur. İskemik hepatite hipotansiyon, hipoksi veya her ikisi birlikte öncülük edebilir ve bu olgularda hipotansiyonun en sık nedeni kardiyovasküler hastalıklardır. Histopatolojik olarak karaciğer biyopsisinde sentrilobüler nekrozun görülmesi tipiktir. Bu makalede miyokard infaktüsü sonrası gelişen hipotansiyon sonucunda karaciğer enzimlerinde ani ve belirgin yükselme ve sonrasında hızlı düşme ile ortaya çıkan iskemik hepatitli bir olguyu sunduk ve hastalığın özelliklerini tartıştık

Keywords

İskemik hepatit, hipotansiyon

A Case of Hypotension Induced Ischemic Hepatitis

Abstract

Ischemic hepatitis is a disease clinically characterized by a sudden rise in serum transaminases and lactic
dehydrogenase levels to 75- to 100-fold normal levels, followed by resolution to near normal levels within 7 to 10
days as a result of an acute circulatory failure due to cardiovascular disease in most of the reported cases. Such
impairment of liver function tests is due to haemodynamic hepatocyte injury that results from failure of hepatic
perfusion. Liver biopsy shows focal centrilobular necrosis. Ischemic hepatitis should be anticipated in all patients
with a recent history of systemic hypotension.
In this paper we describe a case of ischemic hepatitis, in which an acute derangement of liver function tests
occurred as a consequence of myocardial infarction and discuss features of this disease.

Keywords

Ischemic hepatitis, hypotension

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