7. Faure M. Acne and hormones. Rev. Prat 2002; 52: 850-
853.
8. Beylot C. Mechanisms and causes of acne. Rev Prat
2002; 52: 828-830.
9. Goulden V, Clark S M, Cunliffe W J. Postadolescent
acne. Br J Dermatol 1997; 136: 66-70.
10. White GM. Recent findings in the epidemiologic
evidence, classification and subtypes of acne vulgaris. J
AmAcad Dermatol 1998; 39: S34-37.
11. Schroeder B. Early diagnosis, presenting complaints
and management of hyperandrogenism in adolesents.
Curr Womens Health Rep 2001; 1: 124-130.
12. Vexiau P, Baspeyras M, Chaspoux C, Foin N, Allaert
FA, Abramovici Y. Acne in adult women: data from a
national study on the relationship between type of acne
and markers of clinical hyperandrogenism. Ann
Dermatol Venereol 2002; 129: 174-178.
13. Witchel SF. Hyperandrogenism in adolescents.
Adolesc Med 2002;13: 89-99.
14. Chrousos GP, Peck GL, Gross EG, Cutler GB Jr,
Loriaux DL. Adrenal function in women with
idiopathic acne. J Invest Dermatol 1982; 78: 468-471
15. Timpatanapong P, Rojanasakul A. Hormonal profiles
and prevalence of polycystic ovary syndrome in
women with acne. J Dermatol 1997; 24: 223-229.
16. Darley CR, Kirby JD, Besser GM, Munro DD, Edwards
CR, Rees LH. Circulating testosteron, sex hormone
binding globulin and prolactin in women with late
onset or persistent acne vulgaris. Br J Dermatol 1982;
106: 517-522.
17. Aizawa H, Niimura M. Adrenal androgen
abnormalities in women with late onset and persistent
acne.Arch Dermatol Res 1993; 284: 451-455.
18. Maneschi F, Noto G, Pandolfo MC, Palisi F, Martorana
A. Androgenic evalution of women with late-onset or
persistent acne. Minerva Ginecol 1989; 41: 99-103.
19. Vexiau P, Husson C, Chivot M, Brerault JL, Fiet J,
Julien R, Villette JM, Hardy N, Cathelineau G.
Androgen excess in women with acne alone compared
with acne and/or hirsutism. J Invest Der 1990; 94: 279-
283.
20. Azizlerli G, Özarmaðan G, Taklifi H, Sardoðan S.
Aknede hormon düzeyleri. Deri ve Frengi Arþ. 1998;
22: 11-114
21. Erel A, Gökçora N, Himmetoðlu Ö, Gürer MA, Önder
M. Akne vulgariste polikistik over insidansý. Türkderm
1992; 26: 247-250.
22. Bunker CB, Newton JA, Kilborn J, Patel A, Conway
GS, Jacobs HS, Greaves MW, Dowd PM. Most women
with acne have policystic ovaries. Br J Dermatol 1989;
121: 675-680.
23. Jebraili R, Kaur S, Kanwar AJ, Kataria S, Dash RJ.
Hormone profile & polycystic ovaries in acne vulgaris.
Indian J Med Res 1994; 100: 73-76.
24. Serdar Z, Arýca M, Sak N, Pýnar OZ, Derici M. Akne
vulgarisli kadýnlarda polikistik over insidansý ve
hormon düzeyleri. Türkderm 1996; 30: 28-31.
Objective: Our aim was to determine the frequency of post-adolescent acne among acne patients, together with the type and localization of their lesions, concurrent hirsutismus, menstrual irregularities and hormonal abnormalities. Material and Method: Weperformedaretrospective study of patients with acne over 25-year-old, who attended ouroutpatientclinic from 1996 to 2001. Results: Of 1853 acne patients, 175 (9.4%) were diagnosed as post-adolescent acne. Among these 175 post-adolescent acne patients, 143 (81.7%) had history of acne after 25-years ofage, while 32 (18.3%) had persistent acne. The ages of patients with post-adolescent acne were ranging between 25 and 48 (mean value: 29.71 5.08). The duration period of disease was ranging between 1 and 240 months (mean value: 34.37 53.72). 144 of the postadolescent patients (82.3%) were female and 31 (17.2%) were male. When distribution of the lesions were evaluated, there were facial lesions in 125 patients (71.4%), trunk lesions in 11 patients (6.35%), and both face and trunk lesions in 39 patients (22.25%). Of 175 patients, 159 (90.9%) had papulopustular and 16 (9.1%) had nodulocystic acne. Hirsutism was observed in 20 cases (11.4%). When hormones were evaluated in 28 patients with hirsutism and/or irregular menstruation, abnormal levels were determined in 11 (39.3%) of them; while pelvic ultrasonographic evaluations revealed polycystic ovary syndrome in 7 (30.4%) of 23 patients, who had completed their ultrasonographic examinations. Conclusion: Because of the close association with hyperandrogenetism, postadolescent acne patients have to be investigatedthoroughly in the aspect ofhormonal irregularities.
7. Faure M. Acne and hormones. Rev. Prat 2002; 52: 850-
853.
8. Beylot C. Mechanisms and causes of acne. Rev Prat
2002; 52: 828-830.
9. Goulden V, Clark S M, Cunliffe W J. Postadolescent
acne. Br J Dermatol 1997; 136: 66-70.
10. White GM. Recent findings in the epidemiologic
evidence, classification and subtypes of acne vulgaris. J
AmAcad Dermatol 1998; 39: S34-37.
11. Schroeder B. Early diagnosis, presenting complaints
and management of hyperandrogenism in adolesents.
Curr Womens Health Rep 2001; 1: 124-130.
12. Vexiau P, Baspeyras M, Chaspoux C, Foin N, Allaert
FA, Abramovici Y. Acne in adult women: data from a
national study on the relationship between type of acne
and markers of clinical hyperandrogenism. Ann
Dermatol Venereol 2002; 129: 174-178.
13. Witchel SF. Hyperandrogenism in adolescents.
Adolesc Med 2002;13: 89-99.
14. Chrousos GP, Peck GL, Gross EG, Cutler GB Jr,
Loriaux DL. Adrenal function in women with
idiopathic acne. J Invest Dermatol 1982; 78: 468-471
15. Timpatanapong P, Rojanasakul A. Hormonal profiles
and prevalence of polycystic ovary syndrome in
women with acne. J Dermatol 1997; 24: 223-229.
16. Darley CR, Kirby JD, Besser GM, Munro DD, Edwards
CR, Rees LH. Circulating testosteron, sex hormone
binding globulin and prolactin in women with late
onset or persistent acne vulgaris. Br J Dermatol 1982;
106: 517-522.
17. Aizawa H, Niimura M. Adrenal androgen
abnormalities in women with late onset and persistent
acne.Arch Dermatol Res 1993; 284: 451-455.
18. Maneschi F, Noto G, Pandolfo MC, Palisi F, Martorana
A. Androgenic evalution of women with late-onset or
persistent acne. Minerva Ginecol 1989; 41: 99-103.
19. Vexiau P, Husson C, Chivot M, Brerault JL, Fiet J,
Julien R, Villette JM, Hardy N, Cathelineau G.
Androgen excess in women with acne alone compared
with acne and/or hirsutism. J Invest Der 1990; 94: 279-
283.
20. Azizlerli G, Özarmaðan G, Taklifi H, Sardoðan S.
Aknede hormon düzeyleri. Deri ve Frengi Arþ. 1998;
22: 11-114
21. Erel A, Gökçora N, Himmetoðlu Ö, Gürer MA, Önder
M. Akne vulgariste polikistik over insidansý. Türkderm
1992; 26: 247-250.
22. Bunker CB, Newton JA, Kilborn J, Patel A, Conway
GS, Jacobs HS, Greaves MW, Dowd PM. Most women
with acne have policystic ovaries. Br J Dermatol 1989;
121: 675-680.
23. Jebraili R, Kaur S, Kanwar AJ, Kataria S, Dash RJ.
Hormone profile & polycystic ovaries in acne vulgaris.
Indian J Med Res 1994; 100: 73-76.
24. Serdar Z, Arýca M, Sak N, Pýnar OZ, Derici M. Akne
vulgarisli kadýnlarda polikistik over insidansý ve
hormon düzeyleri. Türkderm 1996; 30: 28-31.
Kapulu N, Ermertcan AT, Şahin MT, İnanır İ, Öztürkcan S (April 1, 2003) Post-adolescent Acne in the Spectrum of Acne. Meandros Medical And Dental Journal 4 1 5–8.