SEREBRAL VENÖZ TROMBOZLU HASTALARDA RİSK FAKTÖRLERİ VE ETYOLOJİK SEBEPLERİN VE TEDAVİ ÖZELLİKLERİNİN RETROSPEKTİF İNCELENMESİ

Year 2012, Volume: 13 Issue: 1, 13 - 18, 01.04.2012

Özcan Kocatürk Özlem Coşkun Ruhsen Öcal Levent Ertuğrul İnan Seçil Özkan

Abstract

AMAÇ: Serebral venöz tromboz (SVT) az rastlanılan bir hastalıktır. Farklı klinik tablolarla karşımıza çıkabilir. Hastalığın etyolojisinde pekçok sebep vardır. Bu makalede biz, SVT tanısı alan hastaların hastaneye başvuru semptomlarını ve prognozunu tartışacağız.GEREÇ ve YÖNTEM: Bu çalışma, hastanemizde sinüs ven trombozu nedeniyle takip edilen hastaların hastane verilerinin retrospektif olarak taranması ile yapıldı. Çalışmaya 29 hasta dahil edildi. Tüm hastaların kranial magnetik rezonans (MR) görüntüleme ve MR veya bilgisayarlı tomografi venografi tetkikleri vardı. BULGULAR: Çalışmamızda 27 kadın, 2 erkek toplam 29 hasta vardı. Hastalarımızın yaş ortalaması 34.97 ±12.79 idi. Sadece 8 hastada anormal nörolojik muayene bulgusu vardı (4 hastada papil stazı, 2 hastada konfüzyon, 1 hasta serebeller bozukluk, 1 hasta homonim hemianopsi). Hastaların başvuru semptomları başağrısı (n=19), epileptik nöbetler (n=6), görme bulanıklığı (n=2), diplopi (n=2) ve bir hastanın da vertigosu vardı. Trombotik risk faktörüne 21 hastada rastlandı. En önemli risk faktörleri gebelik, postpartum dönem, oral kontraseptif kullanımı ve kazanılmış hiperkoagülabilitelerdi. SONUÇ: SVT nadir fakat önemli bir durumdur. Bazen hiçbir özelliği olmayan başağrısı bu hastalığın habercisidir. Özellikle gebelik ve postpartum döneminde SVT'ye yatkınlık söz konusudur

Keywords

Serebral venöz sinüs trombozu, risk faktörü, semptom, tedavi

Retospective Analysis of Risk Factors, Etiological Factors and Treatment Options in Patients with Cerebral Venous Thrombosis

Abstract

PURPOSE: Cerebral venous thrombosis (CVT) is not a common disease. It is known to have a varied clinical spectrum. There is too much cause of the etiology of disease. In this manuscript we discussed our patients initial symptoms, cause of CVT and our patients' prognosis. MATERIALS and METHODS: This study was a retrospective database analysis of 29 patients who had CVT followed from 2004 to 2010. All of the patients had cranial magnetic resonans imaging (MR) and Mr /Computarized Tomography (CT) venography. RESULTS: There were 27 female, 2 male in this study. Mean age of the patients was 34.97 ±12.79 years old. Only eight patients had abnormal neurological examination (4 patients papilloedema, 2 patients confusion, 1 patient cerebellar dysfunction, 1 patient homonymous hemianopsia). Initial symptoms of patients were headache(n=19), epileptic seizures (n=6), blurred vision (n=1), diplopia (n=2) and one of the patient had vertigo. Ten patients had only one sinus thrombosis however 19 patients had more than one sinus thrombosis. Thrombotic risk factors were found in 21 patients. Most important risc factor were pregnancy, postpartum condition, oral contraceptive usage and acquired hypercoagulable disease. CONCLUSION: CVT is rare but important condition. Sometimes non specific headache is a herald of this condition. Especially pregnancy and postpartum period are susceptibility of this condition.

Keywords

Cerebral venous sinus thrombosis, risk factors, symptoms, treatment

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