MEMENİN PAGET HASTALIĞI: OLGU SUNUMU

Year 2012, Volume: 13 Issue: 2, 39 - 42, 01.08.2012

Aykut Soyder Serdar Özbaş Füsun Taşkın Meltem Uslu Saime İlkören Muhan Erkuş

Abstract

Yirmi sekiz yaşında kadın hasta, sağ meme başında iki yıldır bulunan topikal tedaviye yanıtsız, kaşıntılı lezyon nedeniyle başvurduğu üniversitemiz dermatoloji polikliniğinde yapılan muayene ve biyopsi sonucunda memenin paget hastalığı tanısı konulması üzerine cerrahi tedavi amacıyla genel cerrahi polikliniğine yönlendirilmişti. Hastanın yapılan meme muayenesinde sağ meme başı ve areolada lokalize keskin sınırlı, eritemli üzerinde sarımsı krut ve seröz akıntı bulunan bir lezyon mevcuttu. Yapılan bilateral meme ve aksilla muayenesinde patoloji saptanmadı. Mamografide sağ meme üst dış kadranda kuşkulu malign özellikler taşıyan pleomorfik mikrokalsifikasyon odağı saptanması üzerine yapılan vakum destekli biyopsi sonucunda intraduktal karsinom gelmesi üzerine hastaya cilt koruyucu mastektomi ve Becker protez ile eş zamanlı meme rekonstrüksiyonu uygulandı. Bu olgu bazında ilgili literatür gözden geçirilerek 30 yaş altı Paget hastalığı tartışılmıştır

Keywords

Meme, Paget hastalığı, intraduktal karsinom, cerrahi tedavi

Paget's Disease of the Breast: A Case Report

Abstract

Our case is a twenty-eight-year-old female lady who admitted to dermatology clinic of our university hospital with itchy lesions on her nipple-areolar complex of her right breast. She had these symptoms and signs for nearly two years and these lesions did not respond to topical treatment. Punch biopsy of the lesion revealed Paget's disease of the breast and the patient was referred to general surgery department. A sharply demarcated erythematous lesion with yellowish crusts were found at the nipple-areolar complex of right breast. No lumps were palpated in both of the breast and axillary examination was normal bilaterally. Mammography of right breast revealed pleomorphic microcalcifications with suspicious features of malignancy in the upper outside quadrant of the breast. Vacuum-assisted biopsy was performed and histopathological examination revealed İntraductal carcinoma. Skin sparing mastectomy and an immediate breast reconstruction with a Becker prosthesis was performed. The incidence of Paget disease below the age of thirty and the clinicopathological features of the disease were discussed in this case report.

Keywords

Breast, Paget's disease, intraductal carcinoma, surgery

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