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NAZOFARENKS'İN EKSTRAMEDÜLLER PLAZMASİTOMU: BİR OLGU SUNUMU

Year 2013, Volume: 14 Issue: 3, 43 - 45, 01.12.2013

Abstract

Ekstramedüller plazmasitom, periferal B lenfositlerden köken alan nadir bir tümördür. Plazma hücre tümörlerinin yaklaşık %3-4'ünü oluşturur. Sıklıkla 5. ve 6. dekada ve daha sıklıkla erkeklerde izlenir. Genellikle baş ve boyun bölgesinde (paranazal sinüs ve nazal kavitenin submukozal dokusunda) yer almasına rağmen tüm baş boyun tümörlerinin ancak %1' inden azını oluşturur. Yavaş büyüyen tümörler olduğu için erken dönemde semptom vermeyebilir. Klinik bulgular tümörün lokalizasyona göre kitle etkisine bağlıdır. Nazofarenks yerleşimli olanlarda nazal obstruksiyon, burun kanaması, kulaklarda dolgunluk hissi ve horlama en sık izlenen bulgulardır. Plazmasitomanın tanısı kitleden alınan biopsinin histolojik incelemesiyle konur. Bu makalede burun tıkanıklığı ile başvuran 67 yaşında erkek hastada nazofarenks tutulumu ile seyreden ekstramedüller plazmositom olgusu bildirilmiştir

References

  • 1. Kırımlıoğlu H, Gürdal C. Subkonjunktival yerleşimli soliter ektramedüller plazmasitom olgusu. İnönü Üniversitesi Tıp Fakültesi Dergisi 20018(3):145-8.
  • 2. Nowak-Sadzikowska J, Weiss M. Extramedullary plasmacytoma of the larynx. Analysis of 5 cases. Eur J Cancer 1998;34 (9):1468.
  • 3. Nofsinger YC, Mirza N, Rowan PT, et al. Head and neck manifestations of plasma cell neoplasms. Laryngoscope 1997;107(6):741-6.
  • 4. Çömez G, Pehlivan Y, Sevinç A, Kervancıoğlu S, Sarıca MA, Tutar E, Camcı C, Adlı M. Maksiller sinüs tutulumlu ekstramedüller plazmositom: Genç bir olgu sunumu. UHOD 2008;2(18):112-5.
  • 5. Welsh J, Westra WH, Eisele D, et al. Solitary plasmacytoma of the epiglottis: A case report and review of the literature. J Laryngol Otol 1998;112(2):174-6.
  • 6. Yavas O, Altundag K, Sungur A. Extramedullary plasmacytoma of nasopharynx and larynx: Synchronous presentation. Am J Hematol 2004;75(4):264-5.
  • 7. Tesei F, Caliceti U, Sorrenti G, et al. Extramedullary plasmocytoma (EMP) of the head and neck: A series of 22 cases. Acta Otorhinolaryngol Ital 1995;15(6):437- 42.
  • 8. Ayan N, Yılmaz B, Çınar F, Çevikbaş U, Gürsel AO Ekstramedüller plazmasitom. K.B.B. ve Baş Boyun Cerrahisi Dergisi 1995;3:73-5.
  • 9. Iseri M, Ozturk M, Ulubil SA. Synchronous presentation of extramedullary plasmacytoma in the nasopharynx and the larynx. Ear Nose Throat J 2009;88(11):E9-12.
  • 10. Rodriguez-de-Velasquez A, Weber AL, Montgomery W. Extramedullary laryngeal plasmacytoma. Ann Otol Rhinol Laryngol 1996;105(6):483-6.
  • 11. Susnerwala SS, Shanks JH, Banerjee SS, et al. Extramedullary plasmacytoma of the head and neck region: Clinicopathological correlation in 25 cases. Br J Cancer 1997;75 (6): 921-7.
  • 12. Holland J, Trenker DA, Wasserman TH, Fineberg B. Plasmacytoma: treatment results and conversion to myeloma. Cancer 1992;69 (6):1513-7.
  • 13. İncesulu A, Yardımcı S, Hücümenoğlu SG, Erkam Ü, Özdemir N, Burun ve Paranazal sinüs yerleşimli ekstramedüller plazmasitom. K.B.B. ve Baş Boyun Cerrahisi Dergisi 2000;8(3):219-5.
  • 14. Corwin J, Lindberg RD. Solitary plasmacytoma of bone vs extramedullary plasmacytoma and their relationship to multiple myeloma. Cancer 1979;43(3):1007-13.

Symptomatic Huge Pericardial Cyst: A Case Report

Year 2013, Volume: 14 Issue: 3, 43 - 45, 01.12.2013

Abstract

Extramedullary plasmacytoma is classified as a peripheral B-cell neoplasm and this tumor uncommon. This tumor comprises 3 to 4% of all plasma cell neoplasms. They usually occur in patients between 5. and 6. decades and more common men. Ususally they arise head and neck area ( paranasal sinus and submucosal nasal cavity ) but less %1 of all head and neck tumors. Their symptoms couldn't seen early period because of growing slowly. Clinical manifestations of tumors are associated with localization. The most clinical manifastation of nasopharyngeeal plasmosytoma is nasal obstruction, epistaxis, aural fullness and snoring. The diagnosis of plasmacytoma is based on and confirmed with histology and immunohistochemistry of biopsy from mass. In this present case, an extramedullar plasmositoma involving the nasopharynx was reported in a 67 years old man presenting with nasal obstruction.

References

  • 1. Kırımlıoğlu H, Gürdal C. Subkonjunktival yerleşimli soliter ektramedüller plazmasitom olgusu. İnönü Üniversitesi Tıp Fakültesi Dergisi 20018(3):145-8.
  • 2. Nowak-Sadzikowska J, Weiss M. Extramedullary plasmacytoma of the larynx. Analysis of 5 cases. Eur J Cancer 1998;34 (9):1468.
  • 3. Nofsinger YC, Mirza N, Rowan PT, et al. Head and neck manifestations of plasma cell neoplasms. Laryngoscope 1997;107(6):741-6.
  • 4. Çömez G, Pehlivan Y, Sevinç A, Kervancıoğlu S, Sarıca MA, Tutar E, Camcı C, Adlı M. Maksiller sinüs tutulumlu ekstramedüller plazmositom: Genç bir olgu sunumu. UHOD 2008;2(18):112-5.
  • 5. Welsh J, Westra WH, Eisele D, et al. Solitary plasmacytoma of the epiglottis: A case report and review of the literature. J Laryngol Otol 1998;112(2):174-6.
  • 6. Yavas O, Altundag K, Sungur A. Extramedullary plasmacytoma of nasopharynx and larynx: Synchronous presentation. Am J Hematol 2004;75(4):264-5.
  • 7. Tesei F, Caliceti U, Sorrenti G, et al. Extramedullary plasmocytoma (EMP) of the head and neck: A series of 22 cases. Acta Otorhinolaryngol Ital 1995;15(6):437- 42.
  • 8. Ayan N, Yılmaz B, Çınar F, Çevikbaş U, Gürsel AO Ekstramedüller plazmasitom. K.B.B. ve Baş Boyun Cerrahisi Dergisi 1995;3:73-5.
  • 9. Iseri M, Ozturk M, Ulubil SA. Synchronous presentation of extramedullary plasmacytoma in the nasopharynx and the larynx. Ear Nose Throat J 2009;88(11):E9-12.
  • 10. Rodriguez-de-Velasquez A, Weber AL, Montgomery W. Extramedullary laryngeal plasmacytoma. Ann Otol Rhinol Laryngol 1996;105(6):483-6.
  • 11. Susnerwala SS, Shanks JH, Banerjee SS, et al. Extramedullary plasmacytoma of the head and neck region: Clinicopathological correlation in 25 cases. Br J Cancer 1997;75 (6): 921-7.
  • 12. Holland J, Trenker DA, Wasserman TH, Fineberg B. Plasmacytoma: treatment results and conversion to myeloma. Cancer 1992;69 (6):1513-7.
  • 13. İncesulu A, Yardımcı S, Hücümenoğlu SG, Erkam Ü, Özdemir N, Burun ve Paranazal sinüs yerleşimli ekstramedüller plazmasitom. K.B.B. ve Baş Boyun Cerrahisi Dergisi 2000;8(3):219-5.
  • 14. Corwin J, Lindberg RD. Solitary plasmacytoma of bone vs extramedullary plasmacytoma and their relationship to multiple myeloma. Cancer 1979;43(3):1007-13.
There are 14 citations in total.

Details

Other ID JA96HD52TM
Journal Section Case Report
Authors

Selvet Erdoğan This is me

Kadri İla This is me

Fatma Demir Kuru This is me

Publication Date December 1, 2013
Published in Issue Year 2013 Volume: 14 Issue: 3

Cite

EndNote Erdoğan S, İla K, Demir Kuru F (December 1, 2013) Symptomatic Huge Pericardial Cyst: A Case Report. Meandros Medical And Dental Journal 14 3 43–45.