Preeklamptik Hastalarda Eritrosit İndeksleri

Year 2015, Volume: 16 Issue: 2, 35 - 42, 01.08.2015

Sümeyra Nergiz Avcıoğlu Selda Demircan Sezer Sündüz Özlem Altınkaya Mert Küçük İmran Kurt Ömürlü Hasan Yüksel

Abstract

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Keywords

Preeklampsi, eritrosit indeksleri, RDW

Erythrocyte Indices in Patients with Preeclampsia

Abstract

Objective: The purpose of study was to investigate erythrocyte indices in patients
with preeclampsia.
Materials and Methods: The study population consisted of 102 patients with
preeclampsia (49 mild, 53 severe preeclampsia) and 98 control pregnant patients.
For the entire study population, red blood cell indices, including baseline mean
corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular
hemoglobin concentration (MCHC), red cell distribution width (RDW), and red
blood cell (RBC) were measured by using an automatic blood counter.
Results: In the preeclampsia group, the median RDW was 15% (13.8-16.57),
whereas in the control group it was 13.9% (13-15.6) (p<0.01). On the other hand,
the mean MCV value was 80.42±7.86 (fL) in preeclampsia group and 83.88±2.31 (fL)
in control group (p=0.003). Besides, the mean MCHC value was 33.66±1.71 (g/dL)
in preeclampsia group and 33.09±1.48 (g/dL) in control group (p=0.012). However
MCH and RBC values were not statistically different between the groups. (p>0.05)
Moreover, subgroup analysis revealed that RDW levels were significantly increased
in preeclampsia subjects than in mild preeclampsia patients (15.4% (13.9-17.45) vs
14.3% (13.7-15.7), p=0.031), MCV levels were decreased (78.81±7.91 (fL) vs 82.16±
7.43 (fL), p=0.03), RBC values were increased (4.16 (3.79-4.85)x(1012/L) vs 3.82 (3.45-
4.34)x(1012/L), (p=0.006)) in patients with severe preeclampsia when compared to
the patients with mild preeclampsia. In the receiver operator characteristic (ROC)
analysis of subjects with and without preeclampsia, RDW and MCV showed high
predictive values (p<0.01). Besides, in ROC analysis of preeclampsia patients with
different severities, RDW and RBC showed the ideal predictive values (p=0.006,
p=0.031, respectively).
Conclusion: Our study results revealed that among the red blood cell indices, only
increased RDW values were associated with both the presence and the severity of
preeclampsia.

Keywords

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