Radiküler Kistlerde Enflamasyon Şiddeti ve Yaş, Cinsiyetle İlişkisi

Year 2024, Volume: 6 Issue: 1, 132 - 137, 31.01.2024

Mürüvvet Akçay Çelik , Havva Erdem , Fadime Gül Salman , Büşra Erşan Erdem , Hilal Balta , Yeliz Kaşko Arıcı , Özge Kaya Korkmaz

https://doi.org/10.37990/medr.1389641

https://izlik.org/JA75RB37MR

Abstract

Amaç: Bu çalışmada bölümümüzdeki radiküler kist olgularında; inflamasyon şiddetinin (aktif ve kronik inflamasyon) değerlendirilmesi, yaş ve cinsiyet ile ilişkisinin araştırılması amaçlandı.
Araç ve Yöntemler: Ordu Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalı'ndaki 01.01.2013-31.01.2022 tarihleri arasındaki radiküler kist olguları çalışmaya dahil edildi. Preparatlar arşivden bulundu ve mikroskobik olarak inflamasyonun şiddeti skorlandı. Kategorik değişkenler arasında var olan ilişkileri incelemek için ki-kare testi kullanıldı. Skor değişkenleri arasında herhangi bir ilişki olup olmadığını belirlemek için korelasyon analizi yapıldı.
Bulgular:Kadınlarda yaş ile kroniklik arasında istatistiksel olarak anlamlı orta düzeyde negatif korelasyon gözlendi (r=-0.410, p=0.013). Erkeklerde aktivite ve kroniklik skorları arasında istatistiksel olarak anlamlı orta düzeyde pozitif korelasyon gözlendi (r=0,592, p<0,001).
Tüm hastalar değerlendirildiğinde aktivite ile kroniklik arasında orta derecede anlamlı negatif korelasyon bulundu (r=0,312, p<0,001). Biri artarken diğeri de artıyordu.
Sonuç: RC olgularında inflamasyonun şiddeti olgudan olguya farklılık gösterebilmektedir. Çalışmamızda olguların çoğunda kronik inflamasyon şiddeti yüksek dereceli (grade 3) izlendi, akut inflamasyon çoğu olguda hafif (grade 1) saptandı.
Histopatolojik olarak inflamasyon şiddetinin ve tipinin belirlenmesinin tanı ve tedavi açısından faydalı olabileceği düşünülmektedir.

Keywords

: Radiküler Kist , Odontojenik Kist , İnflamasyon

Ethical Statement

Araştırmaya başlamadan önce Klinik Araştırmalar Etik Kurulu'ndan 25/03/2022 tarih ve 2022/82 sayılı izin alındı.

Supporting Institution

Ordu Üniversitesi

Project Number

2022/82

Inflammation Severity in Radicular Cysts and Its Relationship with Age and Gender

https://izlik.org/JA75RB37MR

Abstract

Aim: In this study, in radicular cyst cases in our department; It was aimed to evaluate the severity of inflammation (active and chronic inflammation) and to investigate its relationship with age and gender.
Material and Method: Radicular cyst cases between 01.01.2013 and 31.01.2022 in Ordu University, Faculty of Medicine, Department of Pathology were included in the study. Ethical approval was taken from Ordu University Medical School, Clinical Trials Ethical Committee (2022/82). Preparations of the cases were found from the archive and examined microscopically to score the severity of inflammation. To examine any relationships that existed between categorical variables, Chi-square test was used. To determine any relationships between the score variables, correlation analysis was done.
Results: A statistically significant moderate negative correlation was observed between age and chronicity in women (r=-0.410, p=0.013). A statistically significant moderate positive correlation was observed between activity and chronicity scores in men (r=0.592, p<0.001). When all patients were considered, weakly significant negative correlation was found between activity and chronicity (r=0.312, p<0.001). While one was increasing, the other was increasing.
Conclusion: In radicular cyst cases, the severity of inflammation may differ from case to case. In our study, the severity of chronic inflammation was observed as high-grade (grade 3) in most of the cases, acute inflammation was found to be mild (grade 1) in most of the cases. It is thought that determining the severity and type of inflammation in the histopathological evaluation may be beneficial for diagnosis and treatment.

Keywords

Radicular Cyst , Odontogenic Cyst , Inflammation

Ethical Statement

Before beginning the study, permission was granted by the Clinical Research Ethics Committee dated 25/03/2022 and numbered 2022/82.

Supporting Institution

Ordu University

Project Number

2022/82

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