Ankilozan Spondilitli Hastaların Uyku Kalitesinin Çeşitli Değişkenler Açısından Değerlendirilmesi

Öz

Amaç: Bu çalışma, ankilozan spondilitli hastaların uyku kalitesini değerlendirmek ve uyku kalitesini etkileyebilecek faktörleri belirlemek amacıyla yapıldı.
Materyal ve Metot: Tanımlayıcı ve kesitsel tipteki bu çalışma, Aralık 2018-Mayıs 2019 tarihleri arasında Romatoloji polikliniğinde takip edilen, hekim tarafından Modifiye New York Kriterlerine göre ankilozan spondilit tanısı almış, en az 1 yıldır ankilozan spondilit rahatsızlığı olan 70 hasta ve sağlıklı 70 kontrol grubu ile tamamlandı. Veriler, araştırmacılar tarafından oluşturulan “Hasta Bilgi Formu” ve “Pittsburgh Uyku Kalitesi Ölçeği” ile elde edildi. Verilerin değerlendirilmesinde yüzdelik dağılımlar, ki-kare testi, Student t testi ve One-way Anova testi kullanıldı.
Bulgular: Ankilozan spondilitli hastaların %85,8’inin uyku kalitesinin kötü ve Pittsburgh Uyku Kalitesi Ölçeği toplam puanının 7,72±4,38 olduğu, kontrol grubunun ise sadece %17,1’inin uyku kalitesinin kötü olduğu ve Pittsburgh Uyku Kalitesi Ölçeği toplam puanının 3,91±3,57 olduğu belirlendi. Araştırmaya dahil edilen ankilozan spondilitli hastaların yaş, egzersiz yapma, eğitim durumu ve hastalık yılı değişkenleri ile uyku kalitesi bileşenleri arasında ise istatistiksel olarak anlamlı bir ilişki saptandı (p<0,05).
Sonuç: Ankilozan spondilitli hastaların uyku kalitesinin sağlıklı kişilere göre kötü olduğu belirlendi. Sağlık personeli tarafından, ankilozan spondilitli hastalarda uyku problemlerine neden olan durumların tespit edilmesi ve bu durumlara ilişkin gerekli girişimlerin yapılması önerilmektedir.

Anahtar Kelimeler

• Ankilozan spondilit
• Uyku problemi
• Uyku kalitesi

Evaluation of Sleep Quality of Patients with Ankylosing Spondylitis in Terms of Various Variables

Abstract

Aim: This study was conducted to evaluate the sleep quality of patients with ankylosing spondylitis and to determine the factors that may affect sleep quality.
Material and Method: This descriptive and cross-sectional study was conducted between December 2018 and May 2019. It was completed with 70 patients followed in the rheumatology outpatient clinic, diagnosed with ankylosing spondylitis according to the Modified New York Criteria by a physician, and who had ankylosing spondylitis for at least 1 year and 70 healthy controls. The data were obtained using the “Patient Information Form” created by the researchers and “Pittsburgh Sleep Quality Scale” created by the researchers. The analysis of the data was done by descriptive statistics, chi-square test, Student t test and One-way Anova test.
Results: It was determined that 85.8% of the patients with ankylosing spondylitis had poor sleep quality and the Pittsburgh Sleep Quality Scale total score was 7.72 ± 4.38. It was determined that only 17.1% of the control group had poor sleep quality and the total score of Pittsburgh Sleep Quality Scale was 3.91 ± 3.57. A statistically significant relationship was found between age , exercise, educational status and years of illness and sleep quality components of the patients with ankylosing spondylitis included in the study (p <0.05).
Conclusions: It was determined that the sleep quality of patients with ankylosing spondylitis was worse than healthy people. It is recommended by the healthcare personnel to determine the conditions that cause sleep problems in patients with ankylosing spondylitis and to take necessary actions regarding these situations.

Keywords

• Ankylosing spondylitis
• Sleep problem
• Sleep quality

References

1. 1. Duruoz MT, Ulutatar F, Ozturk EC, et al. Assessment of the validity and reliability of the Jenkins Sleep Scale in ankylosing spondylitis. Int J Rheum Dis 2019;22(2):275–279.
2. 2. Öksüz S, Ünal E, Er G, et al. Kuzey Kıbrıs Türk Cumhuriyeti’nde yaşayan ankilozan spondilitli hastaların biyopsikososyal özellikleri arasındaki ilişkinin incelenmesi: pilot çalışma. J Exerc Ther Rehabil 2017;4(1):9-17.
3. 3. Yüksel GA. Sleep quality and restless legs syndrome in patients with ankylosing spondylitis. Haydarpasa Numune Train Res Hosp Med J 2018;59(1):78-83.
4. 4. Mease P, Walsh JA, Baraliakos X, et al. Translating improvements with ixekizumab in clinical trial outcomes into clinical practice: ASAS40, pain, fatigue, and sleep in ankylosing spondylitis. Rheumatol Ther 2019;6(3):435-450.
5. 5. Ölmeztürk ÖÖ, Doğru A, Şahin M. Ankilozan spondilitli erkek hastalarda cinsel disfonksiyonun değerlendirilmesi. SDÜ Sağlık Bilimleri Enstitüsü Dergisi 2018;9(2):19-25.
6. 6. Shen T-C, Liang S-J, Lin C-L, et al. Ankylosing spondylitis and the subsequent risk of sleep disorders: a retrospective population based cohort study in Taiwan. J Intern Med 2016;27(2):79-88.
7. 7. Tyrrell JS, Redshaw CH. Physical activity in ankylosing spondylitis: evaluation and analysis of an eHealth tool. J Innov Health Inform 2016;23(2):169.
8. 8. Urkmez B, Keskin Y. Relationship between sleep quality and physical activity level in patients with ankylosing spondylitis. Mod Rheumatol 2020;30(6):1053-1059.

9. 9. Li Z, Fu T, Wang Y, et al. Sleep disturbances in ankylosing spondylitis: a systematic review and meta-analysis. Psychol Health Med 2019;24(8):911-924.
10. 10. Leverment S, Clarke E, Wadeley A, et al. Prevalence and factors associated with disturbed sleep in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review. Rheumatol Int 2017;37(2):257-2571.
11. 11. Altunalan A, Buğdaycı D, Paker N, et al. Ankilozan spondilitli hastalarda uyku bozukluğunun hastalık aktivitesi ve yaşam kalitesiyle ilişkisi. İstanbul Fiz Tıp Rehabil Derg 2016;(2):21-26.
12. 12. İn E, Turgut T, Gülkesen A, et al. Obstructive sleep apnea syndrome and sleep efficiency in patients with ankylosing spondylitis. Arch Rheumatol 2015;30(4):326-333.
13. 13. Nie A, Wang C, Song Y, et al. Prevalence and factors associated with disturbed sleep in outpatients with ankylosing spondylitis. Clin Rheumatol 2018;37(8):2161-2168.
14. 14. Yolbaş S, Yıldırım A, Düzenci̇ D, et al. Sleep quality, sleeping postures, and sleeping equipment in patients with ankylosing spondylitis. Turk J Med Sci 2017;(47):1198-1205.
15. 15. Jiang Y, Yang M, Lv Q, et al. Prevalence of psychological disorders, sleep disturbance and stressful life events and their relationships with disease parameters in Chinese patients with ankylosing spondylitis. Clin Rheumatol 2018;37(2):407-414.
16. 16. Buysse DJ, Reynolds CF, Monk TH. The Pittsburgh sleep quality index: a new instrument for psychiatric practice and research. Psychiatry Res 1989;28:193-213.
17. 17. Ağargün MY, Kara H, Anlar O. Pittsburgh uyku kalitesi indeksinin geçerlik ve güvenirliği. Türk Psikiyatri Derg 1996;7:107-115.
18. 18. Durmus D, Sarısoy G, Alaylı G, et al. Psychiatric symptoms in ankylosing spondylitis: their relationship with disease activity, functional capacity, pain and fatigue. Compr Psychiatry 2015;62:170-177.
19. 19. Abdulaziez O, Asaad T. Sleep problems in ankylosing spondylitis: polysomnographic pattern and disease related variables. Egypt Rheumatol 2012;34(2):59-65.
20. 20. Li Y, Zhang S, Zhu J, et al. Sleep disturbances are associated with increased pain, disease activity, depression, and anxiety in ankylosing spondylitis: a case-control study. Arthritis Res Ther 2012;14(5):R215.
21. 21. Aydin E, Bayraktar K, Turan Y, et al. Sleep quality in patients with ankylosing spondylitis. Rev Bras Reumatol 2015;55(4):340–345.
22. 22. Deodhar A, Gensler LS, Magrey M, et al. Assessing physical activity and sleep in axial spondyloarthritis: measuring the gap. Rheumatol Ther 2019;6(4):487-501.
23. 23. Masiero S, Bonaldo L, Pigatto M, et al. Rehabilitation treatment in patients with ankylosing spondylitis stabilized with tumor necrosis factor inhibitor therapy. a randomized controlled trial. J Rheumatol 2011;38(7):1335-1342.
24. 24. Millner JR, Barron JS, Beinke KM, et al. Exercise for ankylosing spondylitis: an evidence-based consensus statement. Semin Arthritis Rheum 2016;45(4):411-427.