Case Report
BibTex RIS Cite

Hiponatremi ile Sonuçlanan Kompülsif Su İçme: Bir Pimozid Olgusu

Year 2019, Volume: 1 Issue: 2, 48 - 49, 01.12.2019

Abstract

Pimozid, tremor, rijidite,
distoni, akatizi, jinekomasti gibi yan etkilere neden olabilen bir
antipsikotiktir. Diğer bir nadir yan etkisi psikojenik polidipsiyi takiben
ortaya çıkan hiponatremi tablosudur. Bu olgu sunumunda, günümüzde kardiyak yan
etkileri nedeniyle fazla tercih edilmeyen pimozid ile ilişkili
polidipsi-hiponatremi sendromunu tartıştık. Bu olgu, psikiyatrik bakımı yeterli
olmayan ve antipsikotik kullanan hastalardaki su zehirlenmesi riskini
göstermekte ve bu tür hastalarda düzenli iyon dengesi kontrolünün önemini
vurgulamaktadır.

References

  • 1. Smyj R, Wang XP, Han F. Pimozide. Profiles Drug Subst Excip Relat Methodol 2012;37:287-311.
  • 2. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.
  • 3. Kose S, Akin E, Cetin M. Adverse drug reactions and causality: The Turkish version of Naranjo Adverse Drug Reactions Probability Scale. Psychiatry and Clinical Psychopharmacology 2017;27(2):205-6.
  • 4. Orum MH, Kalenderoglu A, Egilmez OB, Ozen ME, Kapici Y. Hyponatremia associated with repeated use of sodium valproate. Psychiatry and Behavioral Sciences 2018;8(2):93-4.
  • 5. Orum MH, Han-Almis B. Hyponatremia during treatment with the clozapine-amisulpride combination: A suspected association and improvement with dose reduction. Dusunen Adam The Journal of Psychiatry and Neurological Sciences Doi: 10.14744/DAJPNS.2019.00024.
  • 6. Ozen ME, Orum MH, Kalenderoglu A. Escitalopram-induced hyponatremia: A case report. Psychiatry and Behavioral Sciences. Doi: 10.5455/PBS.20171230091731.
  • 7. Koide H. Three cases of hyponatremia during administration of pimozide. No To Hattatsu 1991;23(5):502-5.
  • 8. Nishimura H, Machida K, Nakano H, Shinozaki T, Kasahara H, Ushijima S, et al. A female case of schizophrenia who presented hyponatremia induced by pimozide. Sishin Igaku 1995;37(6):657-60. Doi: 10.11477/mf.1405903894.
  • 9. Leclercq P, Canivet JL, Damas P, Lamy M. A case of severe hyponatremia under pimozide (Orap) administration. Rev Med Liege 1995;50(4):151-2.

Compulsive Water Drinking Resulting in Hyponatremia: A Pimozide Case

Year 2019, Volume: 1 Issue: 2, 48 - 49, 01.12.2019

Abstract

Pimozide is an
antipsychotic can cause side effects such as tremor, rigidity, dystonia,
akathisia, gynecomastia. Another rare side effect is psychogenic polydipsia and
subsequent hyponatremia. In this case report, we discussed the
polydipsia-hyponatremia syndrome associated with pimozide, which is not
currently preferred due to cardiac side effects
.
This case illustrates the risk of water intoxication in antipsychotic-treated
patients with non-psychiatric care and emphasizes the interest of regular ionic
control in such patients.

References

  • 1. Smyj R, Wang XP, Han F. Pimozide. Profiles Drug Subst Excip Relat Methodol 2012;37:287-311.
  • 2. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.
  • 3. Kose S, Akin E, Cetin M. Adverse drug reactions and causality: The Turkish version of Naranjo Adverse Drug Reactions Probability Scale. Psychiatry and Clinical Psychopharmacology 2017;27(2):205-6.
  • 4. Orum MH, Kalenderoglu A, Egilmez OB, Ozen ME, Kapici Y. Hyponatremia associated with repeated use of sodium valproate. Psychiatry and Behavioral Sciences 2018;8(2):93-4.
  • 5. Orum MH, Han-Almis B. Hyponatremia during treatment with the clozapine-amisulpride combination: A suspected association and improvement with dose reduction. Dusunen Adam The Journal of Psychiatry and Neurological Sciences Doi: 10.14744/DAJPNS.2019.00024.
  • 6. Ozen ME, Orum MH, Kalenderoglu A. Escitalopram-induced hyponatremia: A case report. Psychiatry and Behavioral Sciences. Doi: 10.5455/PBS.20171230091731.
  • 7. Koide H. Three cases of hyponatremia during administration of pimozide. No To Hattatsu 1991;23(5):502-5.
  • 8. Nishimura H, Machida K, Nakano H, Shinozaki T, Kasahara H, Ushijima S, et al. A female case of schizophrenia who presented hyponatremia induced by pimozide. Sishin Igaku 1995;37(6):657-60. Doi: 10.11477/mf.1405903894.
  • 9. Leclercq P, Canivet JL, Damas P, Lamy M. A case of severe hyponatremia under pimozide (Orap) administration. Rev Med Liege 1995;50(4):151-2.
There are 9 citations in total.

Details

Primary Language English
Journal Section Case Reports
Authors

Mehmet Hamdi Orum 0000-0002-4154-0738

Oguzhan Bekir Egilmez 0000-0002-6303-1758

Publication Date December 1, 2019
Acceptance Date August 8, 2019
Published in Issue Year 2019 Volume: 1 Issue: 2

Cite

AMA Orum MH, Egilmez OB. Compulsive Water Drinking Resulting in Hyponatremia: A Pimozide Case. Med Records. December 2019;1(2):48-49.

17741

Chief Editors

Assoc. Prof. Zülal Öner
Address: İzmir Bakırçay University, Department of Anatomy, İzmir, Türkiye

Assoc. Prof. Deniz Şenol
Address: Düzce University, Department of Anatomy, Düzce, Türkiye

E-mail: medrecsjournal@gmail.com

Publisher:
Medical Records Association (Tıbbi Kayıtlar Derneği)
Address: Orhangazi Neighborhood, 440th Street,
Green Life Complex, Block B, Floor 3, No. 69
Düzce, Türkiye
Web: www.tibbikayitlar.org.tr

Publication Support:
Effect Publishing & Agency
Phone: + 90 (540) 035 44 35
E-mail:
info@effectpublishing.com
Address: Akdeniz Neighborhood, Şehit Fethi Bey Street,
No: 66/B, Ground floor, 35210 Konak/İzmir, Türkiye
web: www.effectpublishing.com