Yaygın Anksiyete Bozukluğunda Nötrofil Lenfosit Oranı

Year 2020, Volume: 2 Issue: 3, 93 - 97, 26.10.2020

Mehmet Hamdi Örüm

https://doi.org/10.37990/medr.774613

Abstract

Amaç: Yaygın anksiyete bozukluğu (YAB)’ndaki nötrofil lenfosit oranı (NLO) ve monosit lenfosit oranı (MLO) değerlerini incelemeyi amaçladık.
Yöntem: Bu retrospektif çalışmada YAB tanısı alan hastaların (n=43) NLO ve MLO değerleri sağlıklı olguların (n=35) verileri ile karşılaştırıldı.
Bulgular: Hasta ve sağlıklı kontrol grubu, kadınlardan oluşuyordu ve ortalama yaşları benzerdi (p=0,287). Nötrofil sayısı (p<0,001), nötrofil yüzdesi (p=0,008) ve NLO (p=0,011) hasta grubunda anlamlı olarak yüksekti. Lenfosit yüzdesi kontrol grubunda anlamlı olarak daha yüksekti (p=0,018). Monosit sayısı, lenfosit sayısı, monosit yüzdesi ve MLO gruplar arasında benzerdi (p>0,05).
Sonuç: Bu çalışma, YAB’da nötrofil ilişkili parametrelerin artışını göstermesi bakımından önemlidir.

Keywords

Yaygın anksiyete bozukluğu, nötrofil lenfosit oranı, monosit lenfosit oranı, hemogram, tam kan sayımı

Neutrophil to Lymphocyte Ratio in Generalized Anxiety Disorder

Abstract

Aim: We aimed to investigate neutrophil to lymphocyte ratio (NLR) and monocyte to lymphocyte ratio (MLR) values in generalized anxiety disorder (GAD).
Method: In this retrospective study, NLR and MLR of patients diagnosed with GAD (n=43) were compared with the data of healthy subjects (n=35).
Results: The patient and healthy control groups consisted of females and their mean ages were similar (p=0.298). Neutrophil count (p<0.001), percentage of neutrophil (p=0.008), and NLR (p=0.011) were significantly higher in the patient group. The percentage of lymphocyte was significantly higher in the control group (p=0.018). Monocyte count, lymphocyte count, percentage of monocyte, and MLR were similar between the groups (p>0.05).
Conclusion: This study is important in terms of showing the increase of neutrophil related parameters in GAD.

Keywords

Generalized anxiety disorder, neutrophil to lymphocyte ratio, monocyte to lymphocyte ratio, hemogram, complete blood count

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