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Pharmacological Properties of Cistus creticus (Pink Laden) Species

Year 2021, Volume: 3 Issue: 2, 161 - 163, 06.05.2021
https://doi.org/10.37990/medr.818750

Abstract

Cistus creticus (Pink laden) is in the Cistaceae (Ladengeae) family. This herb species grows naturally in the Mediterranean region. It is green, dwarf and shrub, and is defined by the color of the flower. In Turkey, the C.creticus species is commonly in the public referred by names such as hairy laden, pink laden, laden grass, cottonwood and cotton pad. This herb species is used as hemostatic, anti-spasmodic, antidiabetic and anti-inflammatory in the treatment of diseases such as peptic ulcer, diarrhea, high fever, some skin diseases, rheumatic diseases, urinary tract infections and infertility. In our study, the biological structure, chemical composition and antioxidant, antibacterial, antifungal, anti-inflammatory, antiviral, cytotoxic and anticancer properties of the C.creticus (Pink laden) species were reviewed in company with current literature.

References

  • Coode MJE. Cistaceae P. In: Davis PH, Eds. Flora of Turkey and the East Aegean Islands. Vol 1. Edinburgh University Press, Edinburgh, UK; 1965. p.506.
  • Coode MJE. Cistaceae P. In: Davis PH, Mill R, Tan K, Eds. Flora of Turkey and the East Aegean Islands. Vol 10. Edinburgh University Press, Edinburgh, UK; 1988. p.61.
  • Çaşkurlu A, Karadağ AE, Köse YB, Tosun F. In vitro Antifungal Activity of Cistus creticus L. Against Plant Pathogenic Fungi. ACTA Pharmaceutica Sciencia.2020;58(4):413-419. doi:10.23893/1307-2080.APS.05822
  • Güvenç A, Yıldız S, Özkan AM, et al. Antimicrobiological studies on turkish Cistus. species. Pharmaceutical biology. 2005;43(2):178-183. doi:10.1080/13880200590919537
  • Sargın S, Selvi̇ S. A Comparative Leaf Anatomy in The Genus Cistus L. (Cistaceae) Distributed in Turkey. Iğdır Üniv. Fen Bil Enst. Der. 2016;6(2):41-48.
  • Kilic DD, Siriken B, Ertürk Ö, Tanrikulu G, Gül M, Başkan C. Antibacterial, Antioxidant and DNA Interaction Properties of Cistus creticus L. Extracts. Journal of International Environmental Application and Science. 2019;14(3):110-115.
  • Skorić M, Todorović S, Gligorijević N, et al. Cytotoxic activity of ethanol extracts of in vitro grown Cistus creticus subsp. creticus L. on human cancer cell lines. Industrial Crops and Products. 2012;38:153-159. doi:10.1016/j.indcrop.2012.01.017
  • Stępień AE. Cytotoxic and anti-cancer activity of the Cistus species of herbal plants. Eur J Clin Exp Med. 2017;15(2):165–168. doi:10.15584/ejcem.2017.2.11
  • Bayraktar O, Altıok E, Yılmazer Ö, Ruscuklu D, Buyukoz MY. Antioxidant, antimicrobial and cytotoxic activities of extracts from some selected mediterranean shrub species (Maquis). Biointerface Research in Applied Chemistry. 2016;6(4):1437-1444.
  • Lahcen SA, El Hattabi L, Benkaddour R, et al. Chemical composition, antioxidant, antimicrobial and antifungal activity of Moroccan Cistus Creticus leaves. Chemical Data Collections. 2020;26:100346. doi:10.1016/j.cdc.2020.100346
  • Matłok N, Lachowicz S, Gorzelany J, Balawejder M. Influence of Drying Method on Some Bioactive Compounds and the Composition of Volatile Components in Dried Pink Rock Rose (Cistus creticus L.). Molecules. 2020;25(11):2596. Published 2020 Jun 3. doi:10.3390/molecules25112596
  • Stępień A, Aebisher D, Bartusik-Aebisher D. Biological properties of “Cistus species”. Eur J Clin Exp Med. 2018;16(2):127–132. doi:10.15584/ejcem.2018.2.8
  • Demetzos C, Loukis A, Spiliotis V, Zoakis N, Stratigakis N, Katerinopoulos HE. Composition and Antimicrobial Activity of the Essential oil of Cistus creticus L. Journal of Essential Oil Research. 1995;7(4):407-410. doi:10.1080/10412905.1995.9698549
  • Karim H, Boubaker H, Askarne L, et al. Antifungal properties of organic extracts of eight Cistus L. species against postharvest citrus sour rot. Lett Appl Microbiol. 2016;62(1):16-22. doi:10.1111/lam.12507
  • Loizzo MR, Jemia MB, Senatore F, Bruno M, Menichini F, Tundis R. Chemistry and functional properties in prevention of neurodegenerative disorders of five Cistus species essential oils. Food and chemical toxicology. 2013;59:586-594. doi:10.1016/j.fct.2013.06.040
  • Şekeroğlu N, Gezi̇ci̇ S. Koronavirüs Pandemisi ve Türkiye’nin Bazı Şifalı Bitkileri. Anadolu Klin. 2020;25(Special Issue on COVID 19):163-182. doi:10.21673/anadoluklin.724210
  • Güler H, Kara Y. Targeting CoV-2 Spike RBD: ACE-II complex with phenolic compounds from Cistus (Cistus L.) Bee Pollen for COVID-19 treatment by Molecular Docking Study. J.Apit.Nat. 2020;3(1):10-23. doi:10.35206/jan.762734

Cistus creticus (Pembe Laden) Türünün Farmakolojik Özellikleri

Year 2021, Volume: 3 Issue: 2, 161 - 163, 06.05.2021
https://doi.org/10.37990/medr.818750

Abstract

Cistus creticus (Pembe laden), Cistaceae (Ladengiller) familyası içinde yer almaktadır. Bu bitki türü Akdeniz bölgesinde doğal olarak yetişmektedir. Yeşil, bodur ve çalı biçimindedir ve çiçeğinin rengine göre tanımlanmaktadır. Türkiye’de genellikle halk arasında C.creticus türü tüylü laden, pembe laden, laden otu, pamukla ve pamukluk gibi adlarla anılmaktadır. Bu bitki türü toplumda peptik ülser, diyare, yüksek ateş, bazı deri rahatsızlıklarının, romatizmal hastalıkların, idrar yolu enfeksiyonlarının ve kısırlık gibi hastalıkların tedavisinde hemostatik, anti-spazmodik, antidiyabetik ve antienflamatuvar olarak kullanılmaktadır. Çalışmamızda da, C.creticus (Pembe laden) türünün biyolojik yapısı, kimyasal bileşimi; antioksidan, antibakteriyel, antifungal, antiinflamatuar, antiviral, sitotoksik ve antikanser özellikleri güncel literatür eşliğinde derlenmiştir. 

References

  • Coode MJE. Cistaceae P. In: Davis PH, Eds. Flora of Turkey and the East Aegean Islands. Vol 1. Edinburgh University Press, Edinburgh, UK; 1965. p.506.
  • Coode MJE. Cistaceae P. In: Davis PH, Mill R, Tan K, Eds. Flora of Turkey and the East Aegean Islands. Vol 10. Edinburgh University Press, Edinburgh, UK; 1988. p.61.
  • Çaşkurlu A, Karadağ AE, Köse YB, Tosun F. In vitro Antifungal Activity of Cistus creticus L. Against Plant Pathogenic Fungi. ACTA Pharmaceutica Sciencia.2020;58(4):413-419. doi:10.23893/1307-2080.APS.05822
  • Güvenç A, Yıldız S, Özkan AM, et al. Antimicrobiological studies on turkish Cistus. species. Pharmaceutical biology. 2005;43(2):178-183. doi:10.1080/13880200590919537
  • Sargın S, Selvi̇ S. A Comparative Leaf Anatomy in The Genus Cistus L. (Cistaceae) Distributed in Turkey. Iğdır Üniv. Fen Bil Enst. Der. 2016;6(2):41-48.
  • Kilic DD, Siriken B, Ertürk Ö, Tanrikulu G, Gül M, Başkan C. Antibacterial, Antioxidant and DNA Interaction Properties of Cistus creticus L. Extracts. Journal of International Environmental Application and Science. 2019;14(3):110-115.
  • Skorić M, Todorović S, Gligorijević N, et al. Cytotoxic activity of ethanol extracts of in vitro grown Cistus creticus subsp. creticus L. on human cancer cell lines. Industrial Crops and Products. 2012;38:153-159. doi:10.1016/j.indcrop.2012.01.017
  • Stępień AE. Cytotoxic and anti-cancer activity of the Cistus species of herbal plants. Eur J Clin Exp Med. 2017;15(2):165–168. doi:10.15584/ejcem.2017.2.11
  • Bayraktar O, Altıok E, Yılmazer Ö, Ruscuklu D, Buyukoz MY. Antioxidant, antimicrobial and cytotoxic activities of extracts from some selected mediterranean shrub species (Maquis). Biointerface Research in Applied Chemistry. 2016;6(4):1437-1444.
  • Lahcen SA, El Hattabi L, Benkaddour R, et al. Chemical composition, antioxidant, antimicrobial and antifungal activity of Moroccan Cistus Creticus leaves. Chemical Data Collections. 2020;26:100346. doi:10.1016/j.cdc.2020.100346
  • Matłok N, Lachowicz S, Gorzelany J, Balawejder M. Influence of Drying Method on Some Bioactive Compounds and the Composition of Volatile Components in Dried Pink Rock Rose (Cistus creticus L.). Molecules. 2020;25(11):2596. Published 2020 Jun 3. doi:10.3390/molecules25112596
  • Stępień A, Aebisher D, Bartusik-Aebisher D. Biological properties of “Cistus species”. Eur J Clin Exp Med. 2018;16(2):127–132. doi:10.15584/ejcem.2018.2.8
  • Demetzos C, Loukis A, Spiliotis V, Zoakis N, Stratigakis N, Katerinopoulos HE. Composition and Antimicrobial Activity of the Essential oil of Cistus creticus L. Journal of Essential Oil Research. 1995;7(4):407-410. doi:10.1080/10412905.1995.9698549
  • Karim H, Boubaker H, Askarne L, et al. Antifungal properties of organic extracts of eight Cistus L. species against postharvest citrus sour rot. Lett Appl Microbiol. 2016;62(1):16-22. doi:10.1111/lam.12507
  • Loizzo MR, Jemia MB, Senatore F, Bruno M, Menichini F, Tundis R. Chemistry and functional properties in prevention of neurodegenerative disorders of five Cistus species essential oils. Food and chemical toxicology. 2013;59:586-594. doi:10.1016/j.fct.2013.06.040
  • Şekeroğlu N, Gezi̇ci̇ S. Koronavirüs Pandemisi ve Türkiye’nin Bazı Şifalı Bitkileri. Anadolu Klin. 2020;25(Special Issue on COVID 19):163-182. doi:10.21673/anadoluklin.724210
  • Güler H, Kara Y. Targeting CoV-2 Spike RBD: ACE-II complex with phenolic compounds from Cistus (Cistus L.) Bee Pollen for COVID-19 treatment by Molecular Docking Study. J.Apit.Nat. 2020;3(1):10-23. doi:10.35206/jan.762734
There are 17 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Original Articles
Authors

Şükran Amaç 0000-0003-2106-4807

Publication Date May 6, 2021
Acceptance Date February 6, 2021
Published in Issue Year 2021 Volume: 3 Issue: 2

Cite

AMA Amaç Ş. Cistus creticus (Pembe Laden) Türünün Farmakolojik Özellikleri. Med Records. May 2021;3(2):161-163. doi:10.37990/medr.818750

Chief Editors
Prof. Dr. Berkant Özpolat, MD
Department of Thoracic Surgery, Ufuk University, Dr. Rıdvan Ege Hospital, Ankara, Türkiye

Editors
Prof. Dr. Sercan Okutucu, MD
Department of Cardiology, Ankara Lokman Hekim University, Ankara, Türkiye

Assoc. Prof. Dr. Süleyman Cebeci, MD
Department of Ear, Nose and Throat Diseases, Gazi University Faculty of Medicine, Ankara, Türkiye

Field Editors
Assoc. Prof. Dr. Doğan Öztürk, MD
Department of General Surgery, Manisa Özel Sarıkız Hospital, Manisa, Türkiye

Assoc. Prof. Dr. Birsen Doğanay, MD
Department of Cardiology, Ankara Bilkent City Hospital, Ankara, Türkiye

Assoc. Prof. Dr. Sonay Aydın, MD
Department of Radiology, Erzincan Binali Yıldırım University Faculty of Medicine, Erzincan, Türkiye

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PhD, Dr. Evin Mise
Department of Work Psychology, Ankara University, Ayaş Vocational School, Ankara, Türkiye

Dt. Çise Nazım
Department of Periodontology, Dr. Burhan Nalbantoğlu State Hospital, Lefkoşa, North Cyprus

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Department of Statistics, Hacettepe University, Faculty of Science, Ankara, Türkiye

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