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Evaluation of Demographic and Clinical Characteristics of the Patients with Syphilis Who Applied to the Dermatology Clinic of a Tertiary Referral Hospital Between the Years 2019-2023

Year 2023, Volume: 5 Issue: Supplement (1) - Innovations in Medicine and Healthcare in the 100th Year of the Republic, 198 - 202, 19.10.2023
https://doi.org/10.37990/medr.1334413

Abstract

Aim: The aim of this study is to evaluate the demographic and clinical features of syphilis patients followed up in a tertiary referral hospital, and thus to provide current contributions to epidemiological data related to syphilis.
Material and Methods: The demographic characteristics, clinical and laboratory findings, and treatments received of all patients diagnosed with syphilis and followed up in our clinic between January 2019 and June 2023 were evaluated retrospectively.
Results: We included a total of 118 patients, 24 women and 94 men. The average age of the patients was 36.56±5.1 years. Forty-one of the patients (34.7%) were married, 56 were single (47.4%) and the marital status of 21 (17.8%) was unknown. Sixty-two of the patients (52.5%) had primary syphilis , 29 (24.6%) had secondary syphilis and 27 (22.9%) had latent syphilis. When the patients' admission symptoms were evaluated, genital chancre was found in 58 (49.1%), roseola syphilitica in 24 (20.3%), mucous plaque in 11 (9.3%), condyloma lata in 7 (5.9%) and syphilis papulosa psoriasiformis in 3 (2.5%) patients. Twenty-five patients (21.1%) were asymptomatic. Transmission from spouse was in 14 (11.9%) patients while suspicious sexual contact was in 77 (65.3%) patients. The source of transmission was unknown in 27 (22.9%) patients. Response to treatment was obtained in all of the patients who were not lost to follow up. Twenty-two of the patients (18.64%) were HIV positive.
Conclusion: Rising syphilis incidence which is observed globally in the recent years indicates the need to raise the level of public awareness about the disease and its transmission routes. In addition, since it can mimic many diseases, it should always be considered in the differential diagnosis, especially in patients with a history of suspicious sexual contact. It is necessary to investigate other sexually transmitted diseases, especially HIV, in patients diagnosed with syphilis.

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References

  • Oğrum A, Karataş A, İzol B, et al. The demographic findings of patients diagnosed with syphilis in a training and research hospital. Van Tıp Derg. 2019;26:279-84.
  • Adışen E, Öztaş M, Gürer MA. Demographic characteristics of syphilis patients followed between 1994 and 2006. Türkderm. 2008;42:9-12.
  • Arando M, Fernandez-Naval C, Mota-Foix M, et al. Early syphilis: risk factors and clinical manifestations focusing on HIV-positive patients. BMC Infect Dis. 2019;19:727.
  • Workowski KA, Bolan GA. Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recomm Rep. 2015;64:1-137.
  • Karadağ AS, Akdeniz N. Syphilis. Türkiye Klinikleri J Dermatol. Special Topics. 2014;7:40-55.
  • European Centre for Disease Prevention and Control (ECDC). Syphilis and congenital syphilis in Europe. A review of epidemiological trends (2007–2018) and options for response. Stockholm: ECDC; 2019.
  • European Centre for Disease Prevention and Control. Syphilis. In: ECDC. Annual epidemiological report for 2019. Stockholm: ECDC;2022:1-8.
  • Jansen K, Schmidt AJ, Drewes J, et al. Increased incidence of syphilis in men who have sex with men and risk management strategies, Germany, 2015. Eurosurveillance. 2016;21:30382.
  • Centers for Disease Control and Prevention. Sexually transmitted disease surveillance 2019. US Department of Health and Human Services. https://www.cdc.gov/std/statistics/2019/std-surveillance-2019.pdf Access date 14.09.2022
  • TC Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü Bulaşıcı Hastalıklar ve Erken Uyarı Dairesi Başkanlığı.Sifiliz İstatistik. https://hsgm.saglik.gov.tr/tr/bulasici-hastaliklar/sifiliz/sifiliz-liste/sifiliz-istatistik.html Erişim tarihi: 09.12.2021
  • Yürüyen C, Uzunöner Y, Aksaray S. Is Syphilis Seroprevalence Increasing?. Turk Mikrobiyol Cemiy Derg. 2023;53:133-7.
  • Karaosmanoğlu N, Baskovski IGİ, Karaaslan E, et al. The evaluation of syphilis cases who applied to the dermatology clinic in the last two years. Ankara Eğt Arş Hast Derg. 2018;52:69-73.
  • Açıkel C, Babayiğit MA, Kılıç S, et al. Genç erişkin erkeklerin cinsel yolla bulaşan hastalıklar konusunda bilgi düzeyleri (Ankara 2004). TSK Koruyucu Hekimlik Bülteni 2005;4:16-24.
  • Ghanem KG, Erbelding EJ, Cheng WW, Rompalo AM. Doxycycline compared with benzathine penicillin for the treatment of early syphilis. Clin Infect Dis. 2006;42:e45-9.
  • Vergara-Ortega DN, Tapia-Maltos A, Herrera-Ortíz A, et al. High prevalence of Syphilis and Syphilis/HIV coinfection among men who have sex with men who attend meeting places in Mexico. Pathogens. 2023;12:356.
  • Harman R, Şahin Horasan E, Kandemir Ö. Investigation on HIV infection among syphilis patients. Turk Hij Den Biyol Derg. 2021;78:25-30.
Year 2023, Volume: 5 Issue: Supplement (1) - Innovations in Medicine and Healthcare in the 100th Year of the Republic, 198 - 202, 19.10.2023
https://doi.org/10.37990/medr.1334413

Abstract

References

  • Oğrum A, Karataş A, İzol B, et al. The demographic findings of patients diagnosed with syphilis in a training and research hospital. Van Tıp Derg. 2019;26:279-84.
  • Adışen E, Öztaş M, Gürer MA. Demographic characteristics of syphilis patients followed between 1994 and 2006. Türkderm. 2008;42:9-12.
  • Arando M, Fernandez-Naval C, Mota-Foix M, et al. Early syphilis: risk factors and clinical manifestations focusing on HIV-positive patients. BMC Infect Dis. 2019;19:727.
  • Workowski KA, Bolan GA. Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recomm Rep. 2015;64:1-137.
  • Karadağ AS, Akdeniz N. Syphilis. Türkiye Klinikleri J Dermatol. Special Topics. 2014;7:40-55.
  • European Centre for Disease Prevention and Control (ECDC). Syphilis and congenital syphilis in Europe. A review of epidemiological trends (2007–2018) and options for response. Stockholm: ECDC; 2019.
  • European Centre for Disease Prevention and Control. Syphilis. In: ECDC. Annual epidemiological report for 2019. Stockholm: ECDC;2022:1-8.
  • Jansen K, Schmidt AJ, Drewes J, et al. Increased incidence of syphilis in men who have sex with men and risk management strategies, Germany, 2015. Eurosurveillance. 2016;21:30382.
  • Centers for Disease Control and Prevention. Sexually transmitted disease surveillance 2019. US Department of Health and Human Services. https://www.cdc.gov/std/statistics/2019/std-surveillance-2019.pdf Access date 14.09.2022
  • TC Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü Bulaşıcı Hastalıklar ve Erken Uyarı Dairesi Başkanlığı.Sifiliz İstatistik. https://hsgm.saglik.gov.tr/tr/bulasici-hastaliklar/sifiliz/sifiliz-liste/sifiliz-istatistik.html Erişim tarihi: 09.12.2021
  • Yürüyen C, Uzunöner Y, Aksaray S. Is Syphilis Seroprevalence Increasing?. Turk Mikrobiyol Cemiy Derg. 2023;53:133-7.
  • Karaosmanoğlu N, Baskovski IGİ, Karaaslan E, et al. The evaluation of syphilis cases who applied to the dermatology clinic in the last two years. Ankara Eğt Arş Hast Derg. 2018;52:69-73.
  • Açıkel C, Babayiğit MA, Kılıç S, et al. Genç erişkin erkeklerin cinsel yolla bulaşan hastalıklar konusunda bilgi düzeyleri (Ankara 2004). TSK Koruyucu Hekimlik Bülteni 2005;4:16-24.
  • Ghanem KG, Erbelding EJ, Cheng WW, Rompalo AM. Doxycycline compared with benzathine penicillin for the treatment of early syphilis. Clin Infect Dis. 2006;42:e45-9.
  • Vergara-Ortega DN, Tapia-Maltos A, Herrera-Ortíz A, et al. High prevalence of Syphilis and Syphilis/HIV coinfection among men who have sex with men who attend meeting places in Mexico. Pathogens. 2023;12:356.
  • Harman R, Şahin Horasan E, Kandemir Ö. Investigation on HIV infection among syphilis patients. Turk Hij Den Biyol Derg. 2021;78:25-30.
There are 16 citations in total.

Details

Primary Language English
Subjects Disease Surveillance, Epidemiology (Other)
Journal Section Original Articles
Authors

Funda Erduran 0000-0002-3318-2248

Publication Date October 19, 2023
Acceptance Date October 16, 2023
Published in Issue Year 2023 Volume: 5 Issue: Supplement (1) - Innovations in Medicine and Healthcare in the 100th Year of the Republic

Cite

AMA Erduran F. Evaluation of Demographic and Clinical Characteristics of the Patients with Syphilis Who Applied to the Dermatology Clinic of a Tertiary Referral Hospital Between the Years 2019-2023. Med Records. October 2023;5(Supplement (1):198-202. doi:10.37990/medr.1334413

17741

Chief Editors

Assoc. Prof. Zülal Öner
Address: İzmir Bakırçay University, Department of Anatomy, İzmir, Türkiye

Assoc. Prof. Deniz Şenol
Address: Düzce University, Department of Anatomy, Düzce, Türkiye

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