Resveratrol ve kemik üzerine etkileri
Abstract
Resveratrol (RSVL) çeşitli bitkilerden elde edilen doğal bir polifenolik bileşiktir. RSVL’nin, anti-oksidan, anti-inflamatuar, anti-kanserojen, anti-viral, anti-diyabetik, anti-aging, kardiyoprotektif, nöroprotektif ve östrojenik etki gibi çeşitli yararlı etkileri bildirilmiştir. RSVL’nin klinik kullanımı ile ortaya çıkan çeşitli yararlı etkilerine ilaveten bu bileşiğin kemik metabolizması üzerine etkileri de bildirilmiştir. Bu derlemenin amacı RSVL’nin kemik üzerine olan etkilerini değerlendirmektir.
Keywords
References
- Ribeiro FV, Ce´sar-Neto JB, Nociti Jr FH, Sallum EA, Sallum AW, De Toledo S, Casati MZ. Selective cyclooxygenase-2 inhibitor may impair bone healing around titanium implants in rats. J Periodontol 2006;77(10):1731–1735.
- Zupnik J, Kim SW, Ravens D, Karimbux N, Guze K. Factors associated with dental implant survival: a 4-year retrospective analysis. J Periodontol 2011;82(10):1390–1395. Claes L, Recknagel S, Ignatius A. Fracture healing under healthy and inflammatory conditions. Nat Rev Rheumatol 2012;8:133–43.
- Claes L, Recknagel S, Ignatius A. Fracture healing under healthy and inflammatory conditions. Nat Rev Rheumatol 2012;8:133–43.
- Kuroshima S, Kovacic BL, Kozloff KM, McCauley LK, Yamashita J. Intra-oral PTH administration promotes tooth extraction socket healing. J Dent Res 2013;92(6):553-559.
- O’Ryan FS, Lo JC. Bisphosphonate-related osteonecrosis of the jaw in patients with oral bisphosphonate exposure: clinical course and outcomes. J Oral Maxillofac Surg 2012;70(8):1844-1853.
- Casarin RC, Casati MZ, Pimentel SP, Cirano FR, Algayer M, Pires PR, Ghiraldini B, Duarte PM, Ribeiro FV. Resveratrol improves bone repair by modulation of bone morphogenetic proteins and osteopontin gene expression in rats. Int J Oral Maxillofac Surg 2014;43(7):900-906.
- Al-Obaidi MM, Al-Bayaty FH, Al Batran R, Hassandarvish P, Rouhollahi E. Protective effect of ellagic acid on healing alveolar bone after tooth extraction in rat. A histological and immunohistochemical study. Arch Oral Biol 2014, 59: 987-99.
- Amri A, Chaumeil JC, Sfar S, Charrueau C. Administration of resveratrol: What formulation solutions to bioavailability limitations? J Control Release 2012;158(2):182-193.
Details
Primary Language
Turkish
Subjects
Health Care Administration
Journal Section
Review
Authors
Ayşe Özcan Küçük
MERSİN ÜNİVERSİTESİ
Türkiye
Publication Date
December 24, 2017
Submission Date
April 19, 2017
Acceptance Date
September 8, 2017
Published in Issue
Year 2017 Volume: 10 Number: 3