Optimizing tuberculosis control: a comprehensive simulation of integrated interventions using a mathematical model

Olumuyiwa James Peter; Afeez Abidemi; Fatmawati Fatmawati; Mayowa M. Ojo; Festus Abiodun Oguntolu

doi:10.53391/mmnsa.1461011

EN

Optimizing tuberculosis control: a comprehensive simulation of integrated interventions using a mathematical model

Abstract

Tuberculosis (TB) remains a formidable global health challenge, demanding effective control strategies to alleviate its burden. In this study, we introduce a comprehensive mathematical model to unravel the intricate dynamics of TB transmission and assess the efficacy and cost-effectiveness of diverse intervention strategies. Our model meticulously categorizes the total population into seven distinct compartments, encompassing susceptibility, vaccination, diagnosed infectious, undiagnosed infectious, hospitalized, and recovered individuals. Factors such as susceptible individual recruitment, the impact of vaccination, immunity loss, and the nuanced dynamics of transmission between compartments are considered. Notably, we compute the basic reproduction number, providing a quantitative measure of TB transmission potential. Through this comprehensive model, our study aims to offer valuable insights into optimal control measures for TB prevention and control, contributing to the ongoing global efforts to combat this pressing health challenge.

Keywords

Tuberculosis, basic reproduction number, drug resistance, preventive strategies

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Details

Primary Language

English

Subjects

Biological Mathematics, Dynamical Systems in Applications

Journal Section

Research Article

Authors

Olumuyiwa James Peter
0000-0001-9448-1164
Nigeria

Afeez Abidemi
0000-0003-1960-0658
Nigeria

Fatmawati Fatmawati ^*
0000-0002-0418-6629
Indonesia

Mayowa M. Ojo
0000-0002-7867-4713
South Africa

Festus Abiodun Oguntolu
0000-0003-1897-6135
Nigeria

Publication Date

September 30, 2024

Submission Date

March 29, 2024

Acceptance Date

July 15, 2024

Published in Issue

Year 2024 Volume: 4 Number: 3

DOI

https://doi.org/10.53391/mmnsa.1461011

IZ

https://izlik.org/JA67PB87SK

APA

Peter, O. J., Abidemi, A., Fatmawati, F., Ojo, M. M., & Oguntolu, F. A. (2024). Optimizing tuberculosis control: a comprehensive simulation of integrated interventions using a mathematical model. Mathematical Modelling and Numerical Simulation With Applications, 4(3), 238-255. https://doi.org/10.53391/mmnsa.1461011

AMA

1.Peter OJ, Abidemi A, Fatmawati F, Ojo MM, Oguntolu FA. Optimizing tuberculosis control: a comprehensive simulation of integrated interventions using a mathematical model. MMNSA. 2024;4(3):238-255. doi:10.53391/mmnsa.1461011

Chicago

Peter, Olumuyiwa James, Afeez Abidemi, Fatmawati Fatmawati, Mayowa M. Ojo, and Festus Abiodun Oguntolu. 2024. “Optimizing Tuberculosis Control: A Comprehensive Simulation of Integrated Interventions Using a Mathematical Model”. Mathematical Modelling and Numerical Simulation With Applications 4 (3): 238-55. https://doi.org/10.53391/mmnsa.1461011.

EndNote

Peter OJ, Abidemi A, Fatmawati F, Ojo MM, Oguntolu FA (September 1, 2024) Optimizing tuberculosis control: a comprehensive simulation of integrated interventions using a mathematical model. Mathematical Modelling and Numerical Simulation with Applications 4 3 238–255.

IEEE

[1]O. J. Peter, A. Abidemi, F. Fatmawati, M. M. Ojo, and F. A. Oguntolu, “Optimizing tuberculosis control: a comprehensive simulation of integrated interventions using a mathematical model”, MMNSA, vol. 4, no. 3, pp. 238–255, Sept. 2024, doi: 10.53391/mmnsa.1461011.

ISNAD

Peter, Olumuyiwa James - Abidemi, Afeez - Fatmawati, Fatmawati - Ojo, Mayowa M. - Oguntolu, Festus Abiodun. “Optimizing Tuberculosis Control: A Comprehensive Simulation of Integrated Interventions Using a Mathematical Model”. Mathematical Modelling and Numerical Simulation with Applications 4/3 (September 1, 2024): 238-255. https://doi.org/10.53391/mmnsa.1461011.

JAMA

1.Peter OJ, Abidemi A, Fatmawati F, Ojo MM, Oguntolu FA. Optimizing tuberculosis control: a comprehensive simulation of integrated interventions using a mathematical model. MMNSA. 2024;4:238–255.

MLA

Peter, Olumuyiwa James, et al. “Optimizing Tuberculosis Control: A Comprehensive Simulation of Integrated Interventions Using a Mathematical Model”. Mathematical Modelling and Numerical Simulation With Applications, vol. 4, no. 3, Sept. 2024, pp. 238-55, doi:10.53391/mmnsa.1461011.

Vancouver

1.Olumuyiwa James Peter, Afeez Abidemi, Fatmawati Fatmawati, Mayowa M. Ojo, Festus Abiodun Oguntolu. Optimizing tuberculosis control: a comprehensive simulation of integrated interventions using a mathematical model. MMNSA. 2024 Sep. 1;4(3):238-55. doi:10.53391/mmnsa.1461011

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The published articles in MMNSA are licensed under a Creative Commons Attribution 4.0 International License

Optimizing tuberculosis control: a comprehensive simulation of integrated interventions using a mathematical model

Abstract

Optimizing tuberculosis control: a comprehensive simulation of integrated interventions using a mathematical model

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

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Cited By

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Analysis of mathematical transmission in the SEI L 1 L 2R tuberculosis model

Temporal dynamics of immunity: modeling susceptibility delay in antibody-shielded populations