Research Article

Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma

Volume: 2 Number: 2 August 1, 2022
  • Zehra Pınar Koç *
  • Pınar Pelin Özcan
  • Emel Sezer
  • Ahmet Dağ
  • Ferah Tuncel Daloğlu
  • Tolgay Tuyan İlhan

Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma

Abstract

Objective: The F-18 FDG PET/CT imaging is a commonly preferred imaging modality for staging breast carcinoma. The gynecological tumors are more frequently present in patients with breast carcinoma compared to the general population. The aim of this study was to investigate the clinical importance of the uterine and adnexal uptake observed incidentally in the F-18 FDG PET/CT imaging of breast carcinoma. Patients and Methods: The F-18 FDG PET/CT images (performed for staging or treatment response evaluation purposes) of the patients (sixty-six women, the mean age 49,5±12,6 years) with suspicious uterine and/or adnexal uptake were included in the study. The imaging results were compared with pelvic examination data as well as operative and pathology results. Results: In the imaging studies the increased FDG uptake sites were the primary tumor (mean 27, 3 (24,5) mm, SUVmax=31,3 (20) in 35 patients, and 22 patients additional axillar metastases and distant metastasis in 19 patient were observed. Among the patients involved in the study 29 had unilateral adnexal uptake and/or lesion and/or uterine uptake and others had suspicious findings without increased uptake. Conclusion: Referral of the patients for gynecological examination with coincident uterine and adnexal abnormal uptake in the F-18 FDG PET/CT would be the appropriate approach for the patients with the diagnosis of breast cancer.

Keywords

References

  1. 1. Ishimori, T., Patel, P. V., & Wahl, R. L. (2005). Detection of unexpected additional primary malignancies with PET/CT. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 46(5), 752–757.
  2. 2. Agress, H., Jr, & Cooper, B. Z. (2004). Detection of clinically unexpected malignant and premalignant tumors with whole-body FDG PET: histopathologic comparison. Radiology, 230(2), 417–422. https://doi.org/10.1148/radiol.2302021685
  3. 3. Wooster, R., & Weber, B. L. (2003). Breast and ovarian cancer. The New England journal of medicine, 348(23), 2339–2347. https://doi.org/10.1056/NEJMra012284
  4. 4. Lerman H, Metser U, Grisaru D, Fishman A, Lievshitz G, Even-Sapir E. Normal and abnormal 18F-FDG endometrial and ovarian uptake in pre- and postmenopausal patients: assessment by PET/CT. J Nucl Med. 2004;45:266–71.
  5. 5. Park, S. A., Lee, K. M., Choi, U., Kim, H. S., Kim, H. W., & Song, J. H. (2010). Normal Physiologic and Benign Foci with F-18 FDG Avidity on PET/CT in Patients with Breast Cancer. Nuclear medicine and molecular imaging, 44(4), 282–289. https://doi.org/10.1007/s13139-010-0055-7
  6. 6. Razia, S., Nakayama, K., Tsukao, M., Nakamura, K., Ishikawa, M., Ishibashi, T., Ishikawa, N., Sanuki, K., Yamashita, H., Ono, R., Hossain, M. M., Minamoto, T., & Kyo, S. (2017). Metastasis of breast cancer to an endometrial polyp, the cervix and a leiomyoma: A case report and review of the literature. Oncology letters, 14(4), 4585–4592. https://doi.org/10.3892/ol.2017.6822
  7. 7. Akhtar, A., Ratra, A., Puckett, Y., Sheikh, A. B., & Ronaghan, C. A. (2017). Synchronous Uterine Metastases from Breast Cancer: Case Study and Literature Review. Cureus, 9(11), e1840. https://doi.org/10.7759/cureus.1840
  8. 8. Abrams HL, Spiro R and Goldstein N. Metastases in carcinoma: Analysis of 1000 autopside cases. Cancer 1950;3:74-85

Details

Primary Language

English

Subjects

Oncology and Carcinogenesis

Journal Section

Research Article

Authors

Zehra Pınar Koç * This is me
0000-0002-3274-5790
Türkiye

Pınar Pelin Özcan This is me
0000-0003-0147-2678
Türkiye

Ferah Tuncel Daloğlu This is me
0000-0001-6506-9461
Türkiye

Tolgay Tuyan İlhan This is me
0000-0002-2186-441X
Türkiye

Publication Date

August 1, 2022

Submission Date

July 1, 2022

Acceptance Date

July 15, 2022

Published in Issue

Year 2022 Volume: 2 Number: 2

APA
Koç, Z. P., Özcan, P. P., Sezer, E., Dağ, A., Tuncel Daloğlu, F., & İlhan, T. T. (2022). Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma. Molecular Oncologic Imaging, 2(2), 6-11. https://izlik.org/JA56ZJ99ZA
AMA
1.Koç ZP, Özcan PP, Sezer E, Dağ A, Tuncel Daloğlu F, İlhan TT. Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma. Molecular Oncologic Imaging. 2022;2(2):6-11. https://izlik.org/JA56ZJ99ZA
Chicago
Koç, Zehra Pınar, Pınar Pelin Özcan, Emel Sezer, Ahmet Dağ, Ferah Tuncel Daloğlu, and Tolgay Tuyan İlhan. 2022. “Coincident Pelvic Uptake in the F-18 FDG PET CT Imaging in Patients With the Diagnosis of Breast Carcinoma”. Molecular Oncologic Imaging 2 (2): 6-11. https://izlik.org/JA56ZJ99ZA.
EndNote
Koç ZP, Özcan PP, Sezer E, Dağ A, Tuncel Daloğlu F, İlhan TT (August 1, 2022) Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma. Molecular Oncologic Imaging 2 2 6–11.
IEEE
[1]Z. P. Koç, P. P. Özcan, E. Sezer, A. Dağ, F. Tuncel Daloğlu, and T. T. İlhan, “Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma”, Molecular Oncologic Imaging, vol. 2, no. 2, pp. 6–11, Aug. 2022, [Online]. Available: https://izlik.org/JA56ZJ99ZA
ISNAD
Koç, Zehra Pınar - Özcan, Pınar Pelin - Sezer, Emel - Dağ, Ahmet - Tuncel Daloğlu, Ferah - İlhan, Tolgay Tuyan. “Coincident Pelvic Uptake in the F-18 FDG PET CT Imaging in Patients With the Diagnosis of Breast Carcinoma”. Molecular Oncologic Imaging 2/2 (August 1, 2022): 6-11. https://izlik.org/JA56ZJ99ZA.
JAMA
1.Koç ZP, Özcan PP, Sezer E, Dağ A, Tuncel Daloğlu F, İlhan TT. Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma. Molecular Oncologic Imaging. 2022;2:6–11.
MLA
Koç, Zehra Pınar, et al. “Coincident Pelvic Uptake in the F-18 FDG PET CT Imaging in Patients With the Diagnosis of Breast Carcinoma”. Molecular Oncologic Imaging, vol. 2, no. 2, Aug. 2022, pp. 6-11, https://izlik.org/JA56ZJ99ZA.
Vancouver
1.Zehra Pınar Koç, Pınar Pelin Özcan, Emel Sezer, Ahmet Dağ, Ferah Tuncel Daloğlu, Tolgay Tuyan İlhan. Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma. Molecular Oncologic Imaging [Internet]. 2022 Aug. 1;2(2):6-11. Available from: https://izlik.org/JA56ZJ99ZA