Mortality Analysis by Means of F-18 FDG PET/CT in High Grade Extranodal Head and Neck Lymphoma

Abstract

The aim of this study is to decide the diagnostic value of F-18 FDG PET/CT in the predictive value of survival of the patients with diagnosis of head and neck extranodal lymphoma (ENL). Materials and Methods: Eighteen patients (10 F, 8 M; mean: 54,3±21.1 years old) with the diagnosis of head and neck ENL were included in the study. The FDG PET/CT images of the patients were analyzed retrospectively and the maximum standardized uptake value (SUVmax) levels of the primary tumors at the initial evaluation were recorded and compared with mortality results of the patients in the follow up. Results: The initial SUVmax levels of the patients with progressive and stable-responsive disease were not significantly different and the difference between the SUVmax levels of the patients who died was not statistically significant. Discussion and Conclusion: FDG PET/CT is the gold standard imaging modality in the diagnosis and follow up of the lymphoma. Head and neck ENL is a special group of lymphoma with different prognosis. This analysis demonstrated that the mortality of the patients with high grade head and neck ENL might not be predicted by means of initial SUVmax levels.

Keywords

• lymphoma
• extranodal
• FDG
• SUV
• PET/CT

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