Psoriasis triggered by bupropion in a patient with major depression

Abstract

Despite extensive use of antidepressants in patients with psoriasis, there have been very few case reports of antidepressant-related psoriasis. In this case, a patient with major depression who was treated with varies types of antidepressants including fluoxetine, reboxetine, bupropion, and venlafaxine, and in who pre-existing psoriatic lesions were aggravated after bupropion treatment. Clinicians should be aware of the influence of bupropion to aggravate pre-existing psoriasis.

Keywords

• psoriasis, major depression, bupropion, antidepressant, side effect

Major depresyon hastasında bupropion tedavisiyle tetiklenen psöriasis

Öz

Antidepresanların psöriazis hastalarında sıkça kullanılmalarına karşın, çok az sayıda antidepresanlar ile ilişkili psöriazis vakaları bulunmaktadır. Bu olguda major depresyonu olan hasta, sıra ile fluoksetin, reboksetin, bupropion ve venlafaksin gibi farklı grup antidepresanlar ile tedavisi uygulanmıştır ve hastanın bupropion tedavisi sonrasında önceden var olan psöriatik lezyonları alevlenmiştir. Klinisyenler bupropionun daha önceden var olan psöriazisi alevlendirici etkilerinin farkında olmalıdır.

Anahtar Kelimeler

• psöriazis, major depresyon, bupropion, antidepresan, yan etki

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