Each patients cancer is like fingerprint: where are we in molecular profiling in breast cancer diagnosis?

Volume: 1 Number: 1 March 1, 2014
  • Burcak Karaca
  • Harika Atmaca
  • Emir Bozkurt
  • Ruchan Uslu
EN TR

Each patients cancer is like fingerprint: where are we in molecular profiling in breast cancer diagnosis?

Abstract

Breast cancer is the leading cause of cancer related deaths in women. Since every patient has unique molecular profile of tumorigenesis, efficient treatment choice should be tailored according to each patients gene expression profile. Therefore, it is critical to investigate molecular patterns of each patient before choosing the right treatment. For this aim, many commercial breast cancer subtyping methods are available. This review focuses on new developments and methods in molecular profiling of breast cancer.

Keywords

References

  1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA: a cancer journal for clinicians. 2011;61(2):69-90.
  2. Gruvberger S, Ringner M, Chen Y, Panavally S, Saal LH, Borg A, et al. Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns. Cancer research. 2001;61(16):5979-84.
  3. Bertucci F, Borie N, Ginestier C, Groulet A, Charafe-Jauffret E, Adelaide J, et al. Identification and validation of an ERBB2 gene expression signature 2004;23(14):2564-75. cancers. Oncogene.
  4. Bieche I, Lerebours F, Tozlu S, Espie M, Marty M, Lidereau R. Molecular profiling of inflammatory breast cancer: identification of a poor-prognosis gene expression signature. Clinical cancer research : an official journal of the American Association for Cancer Research. 2004;10(20):6789-95.
  5. Perou CM, Sorlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, et al. Molecular portraits of human 2000;406(6797):747-52. tumours. Nature.
  6. West M, Blanchette C, Dressman H, Huang E, Ishida S, Spang R, et al. Predicting the clinical status of human breast cancer by using gene expression profiles. Proceedings of the National Academy of Sciences of the United States of America. 2001;98(20):11462-7.
  7. van 't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, Mao M, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 2002;415(6871):530-6.
  8. Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proceedings of the National Academy of Sciences of the United States of America. 2001;98(19):10869-74.

Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Burcak Karaca This is me

Harika Atmaca This is me

Emir Bozkurt This is me

Ruchan Uslu This is me

Publication Date

March 1, 2014

Submission Date

December 26, 2014

Acceptance Date

-

Published in Issue

Year 2014 Volume: 1 Number: 1

APA
Karaca, B., Atmaca, H., Bozkurt, E., & Uslu, R. (2014). Each patients cancer is like fingerprint: where are we in molecular profiling in breast cancer diagnosis? Medical Science and Discovery, 1(1), 2-8. https://doi.org/10.17546/msd.70695
AMA
1.Karaca B, Atmaca H, Bozkurt E, Uslu R. Each patients cancer is like fingerprint: where are we in molecular profiling in breast cancer diagnosis? Med Sci Discov. 2014;1(1):2-8. doi:10.17546/msd.70695
Chicago
Karaca, Burcak, Harika Atmaca, Emir Bozkurt, and Ruchan Uslu. 2014. “Each Patients Cancer Is Like Fingerprint: Where Are We in Molecular Profiling in Breast Cancer Diagnosis?”. Medical Science and Discovery 1 (1): 2-8. https://doi.org/10.17546/msd.70695.
EndNote
Karaca B, Atmaca H, Bozkurt E, Uslu R (March 1, 2014) Each patients cancer is like fingerprint: where are we in molecular profiling in breast cancer diagnosis? Medical Science and Discovery 1 1 2–8.
IEEE
[1]B. Karaca, H. Atmaca, E. Bozkurt, and R. Uslu, “Each patients cancer is like fingerprint: where are we in molecular profiling in breast cancer diagnosis?”, Med Sci Discov, vol. 1, no. 1, pp. 2–8, Mar. 2014, doi: 10.17546/msd.70695.
ISNAD
Karaca, Burcak - Atmaca, Harika - Bozkurt, Emir - Uslu, Ruchan. “Each Patients Cancer Is Like Fingerprint: Where Are We in Molecular Profiling in Breast Cancer Diagnosis?”. Medical Science and Discovery 1/1 (March 1, 2014): 2-8. https://doi.org/10.17546/msd.70695.
JAMA
1.Karaca B, Atmaca H, Bozkurt E, Uslu R. Each patients cancer is like fingerprint: where are we in molecular profiling in breast cancer diagnosis? Med Sci Discov. 2014;1:2–8.
MLA
Karaca, Burcak, et al. “Each Patients Cancer Is Like Fingerprint: Where Are We in Molecular Profiling in Breast Cancer Diagnosis?”. Medical Science and Discovery, vol. 1, no. 1, Mar. 2014, pp. 2-8, doi:10.17546/msd.70695.
Vancouver
1.Burcak Karaca, Harika Atmaca, Emir Bozkurt, Ruchan Uslu. Each patients cancer is like fingerprint: where are we in molecular profiling in breast cancer diagnosis? Med Sci Discov. 2014 Mar. 1;1(1):2-8. doi:10.17546/msd.70695