Examination of P300 in Veteran Males: Aging, Physical Activity and Cognitive Processing

Abstract

Aim: In the recent years, the effects of long term exercise on physiological systems have been thoroughly investigated. The aim of this study was to investigate the effect of long-term physical exercise on cognitive processing in elderly male athletes. Materials and Methods: Master athletes who had been exercising regularly (EME), healthy sedentary elderly volunteers (HSE) and healthy sedentary middle-aged volunteers (HSMA) were included in the study. Indirect maximum oxygen uptake capacity (VO2max) was determined by Astrand Test. Cognitive function (P300) was recorded at the same time of the day and in the same setting in all subjects Results: Mean latency of P300 was 320.50±20.4 ms in EME, 344.70±24.48 ms in the HSE and 303.20±33.79 ms in the HSMA group. Mean amplitudes of P300 were 11.03 ±7.60 mV, 10.39±5.48 mV and 23.90 ±9.56mV in the EME, HSE and HSMA groups, respectively. Mean indirect maximum oxygen uptake capacity was 32.18±5.7, 18.07±5.0 and 15.8±5.0 ml/min/kg in the HSE, EME and HSMA groups, respectively Conclusion: Results of this study indicate that long-term regular exercise affected cognitive functions positively. Even though the difference in P300 latency and amplitude between EME and HSMA groups was not statistically significant, that between HSE and HSMA was. We conclude that long-term exercise slows down the age-related decline in physical and cognitive performance

Keywords

• P300, Aerobic exercise, Aging, Male

Examination of P300 in Veteran Males: Aging, Physical Activity and Cognitive Processing

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References

1. 1. Bashore TR. Age, physical fitness, and mental processing speed. Annual review of gerontology & geriatrics. 1989;9:120-44.
2. 2. Dustman RE, Emmerson R, Shearer D. Physical activity, age and cognitive neuropsychological function. Journal of Aging Physical Activity. 1994;2:143-181.
3. 3. Dustman RE, Emmerson RY, Ruhling RO, Shearer DE, Steinhaus LA, Johnson SC, et al. Age and fitness effects on EEG, ERPs, visual sensitivity, and cognition. Neurobiology of aging. 1990;11(3):193-200.
4. 4. Hawkins HL, Kramer AF, Capaldi D. Aging, exercise, and attention. Psychology and aging. 1992;7(4):643-53.
5. 5. Spirduso WW. Physical fitness, aging, and psychomotor speed: a review. Journal of gerontology. 1980;35(6):850- 65.
6. 6. Dustman RE, Ruhling RO, Russell EM, Shearer DE, Bonekat HW, Shigeoka JW, et al. Aerobic exercise training and improved neuropsychological function of older individuals. Neurobiology of aging. 1984;5(1):35- 42.
7. 7. Baylor AM, Spirduso WW. Systematic aerobic exercise and components of reaction time in older women. Journal of gerontology. 1988;43(5):P121-6.
8. 8. Blumenthal JA, Madden DJ. Effects of aerobic exercise training, age, and physical fitness on memory-search performance. Psychology and aging. 1988;3(3):280-5.

9. 9. Dustman RE, Emmerson RY, Ruhling RO, Shearer DE, Steinhaus LA, Johnson SC, et al. Age and fitness effects on EEG, ERPs, visual sensitivity, and cognition. Neurobiology of aging. 1990;11(3):193-200.
10. 10. Stones MJ, Kozma A. Age, exercise, and coding performance. Psychology and aging. 1989;4(2):190-4.
11. 11. Cote J, Salmela J, Papathanasopoulu KP. Effects of progressive exercise on attentional focus. Perceptual and motor skills. 1992;75(2):351-4.
12. 12. Anderson KJ. Arousal and the inverted-U hypothesis: A critique of Neiss's “reconceptualizing arousal”. Psychological Bulletin. 1990;107:96-100.
13. 13. Arcelin R, Delignieres D, Brisswalter J. Selective effects of physical exercise on choice reaction processes. Perceptual and motor skills. 1998;87(1):175-85.
14. 14. Donchin E, Coles MGH. Is the P300 component a manifestation of context updating? Behavioral and Brain Sciences. 1988;11:357-374.
15. 15. Polich J. Clinical application of the P300 event-related brain potential. Physical medicine and rehabilitation clinics of North America. 2004;15(1):133-61.
16. 16. Polich J, Kok A. Cognitive and biological determinants of P300: an integrative review. Biological psychology. 1995;41(2):103-46.
17. 17. Lardon MT, Polich J. EEG changes from long-term physical exercise. Biological psychology. 1996;44(1):19- 30.
18. 18. Polich J, Lardon MT. P300 and long-term physical exercise. Electroencephalography and clinical neurophysiology. 1997;103(4):493-8.
19. 19. Angevaren M, Aufdemkampe G, Verhaar HJ, Aleman A, Vanhees L. Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment. The Cochrane database of systematic reviews. 2008(2):CD005381.
20. 20. McDowell K, Kerick SE, Santa Maria DL, Hatfield BD. Aging, physical activity, and cognitive processing: an examination of P300. Neurobiology of aging. 2003;24(4):597-606.
21. 21. Daffner KR, Ryan KK, Williams DM, Budson AE, Rentz DM, Scinto LF, et al. Age-related differences in novelty and target processing among cognitively high performing adults. Neurobiology of aging. 2005;26(9):1283-95.
22. 22. Soltani M, Knight RT. Neural origins of the P300. Critical reviews in neurobiology. 2000;14(3-4):199-224.
23. 23. Astrand PO, Rodahl K. Training Methods and Biological Long-term. Textbook of work physiology. New York: McGraw Hill Co. 1986.
24. 24. Bashore TR, van der Molen MW. Discovery of the P300: a tribute. Biological psychology. 1991;32(2-3):155-71.
25. 25. Johnson R, Jr. On the neural generators of the P300 component of the event-related potential. Psychophysiology. 1993;30(1):90-7.
26. 26. Polich J. P300 in clinical applications: Meaning, method and measurement. Niedermeyer E, Lopes da Silva F, editors. Electroencephalography: Basic principles, clinical applications, and related fields. Baltimore: Williams & Wilkins. 1993.
27. 27. Kok A. Internal and external control: a two-factor model of amplitude change of event-related potentials. Acta psychologica. 1990;74(2-3):203-36.
28. 28. Boutcher SH, Landers DM. The effects of vigorous exercise on anxiety, heart rate, and alpha activity of runners and nonrunners. Psychophysiology. 1988;25(6):696-702.
29. 29. Geisler MW, Squires NK. Exercise and pain differentially affect the P300 event-related brain potential. Psychophysiology. 1992;29:14.
30. 30. Bashore TR, Goddard PH. Preservative and restorative effects of aerobic fitness on the age related slowing of mental speed. Cerella J, Rhybash J, Hoyer W, editors. Adult Information Processing: Limits On Loss. New York: Academic Press. 1993.
31. 31. Dustman RE, Shearer DE, Emmerson RY. EEG and event-related potentials in normal aging. Progress in neurobiology. 1993;41(3):369-40