Examination of echocardiographic parameters for the early diagnosis of cardiac dysfunction in beta thalassemia major patients

Abstract

Objective: This study aimed to determine the utility of tissue Doppler, pulse-wave Doppler, and conventional echocardiography for the detection of cardiac dysfunction in the early period in beta thalassemia patients. Methods: Forty beta thalassemia major patients undergoing regular blood transfusion and chelation therapy and 30 healthy controls with similar demographic factors were included in the study. Both the patient and control groups were examined with, tissue Doppler, pulse-wave Doppler, motion-mode echocardiography. Ferritin values and T2* magnetic resonance measurements were recorded for those in the patient group. Results: Diastolic dysfunction indicators like early ventricular filling rate, atrial contraction rate, mitral A wave time, and reverse pulmonary venous flow velocity were higher in the patient group (p

Keywords

• Beta thalassemia major, cardiac dysfunction, pulse-wave Doppler echocardiography, tissue Doppler echocardiography, conventional echocardiography, T2* magnetic resonance

Examination of echocardiographic parameters for the early diagnosis of cardiac dysfunction in beta thalassemia major patients

Öz

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