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Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery

Year 2015, Volume: 2 Issue: 4, 275 - 77, 27.04.2015

Mustafa Zor Abdullah Ozer , Huseyin Demirtas Yigit Kilic Baris Mardin

Abstract

One year old patient followed with tetralogy of fallot (TOF) was admitted to our service for surgical repair. Ventricular septal defect (VSD) was repaired with a Dacron patch. The infundibular  muscle was resected to allow for unobstructed flow of blood to the pulmonary valve and the area above the pulmonary valve was opened with a polytetrafluoroethylene (PTFE) patch. The patient was intubated three times bacause of the  atelectasis ocurred in the lungs after the surgery. Atelectasis was treated with nebulised dornase alpha. It avoided the recurrence of atelectasis and the patient was discharged.

Keywords

Atelectasis; Dornase Alpha (Pulmozyme®); Congenital Heart Surgery

References

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  • Felcar JM, Guitti JCS, Marson AC, Cardoso JR. Fisioterapiapré-operatória na prevenção das complicações pulmonares emcirurgia cardíaca pediátrica. Rev Bras Cir Cardiovasc. 2008; 23(3):383-8.
  • Andrejaitiene J, Sirvinskas E, Bolys R. The influence of cardiopulmonary bypass on respiratory dysfunction in early postoperative period. Medicina (Kaunas). 2004; 40(Suppl1):7-12.
  • Kavanagh BP. Perioperative atelectasis. Minerva Anestesiol. 2008; 74(6):285-7.
  • Undern-Sternberg BS, Petak F, Saudan S, Pellegrini M, Erb TO, Habre W. Effect of cardiopulmonary bypass and aortic clamping on functional residual capacity and ventilation distribution in children. J Thorac Cardiovasc Surg. 2007; 134(5): 1193-8.
  • Nina RVAH, Gama MEA, Santos AM, Nina VJS, Figueiredo NETO JA, Mendes VGG, et al. O escore de risco ajustado para cirurgia em cardiopatias congênitas (RACHS-1) pode ser aplicado em nosso meio? Rev Bras Cir Cardiovasc. 2007; 22(4): 425-31.
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  • Lee A. Fleisher. Anesthesia and uncommon disease. Elsevier Health Sciences, 2012; Sixth Ed. pp (6-7)
  • Oh AY, Kim YH, Kim BK, Kim HS, Kim CS Unexpected tracheomalacia in Marfan syndrome during general anesthesia for correction of scoliosis. Anesth Analg 2002; 95: 331-2.
  • Kanter RK, Pollack MM, Wright WW, et al. Treatment of severe tracheobronchomalacia with continuous positive airway pressure (CPAP). Anesthesiology 1982; 57: 54–6.
  • Shah PL, Scott SF, Knight RA, et al. In vivo effect of rhDNase 1 on sputum in patients with cystic fibrosis. Thorax 1996;51(2):119-25.
  • Hassan NO, Chess PR. Rescue use of DNase in critical lung atelectasis and mucus retention in premature neonates. Pediatrics 2001;108:468.
  • Toulemiat B, Conoscenti G, Fine J. Recombinant human Dnase in management of lobar atelectasis due to retained secretions. Thorax 1995;50:1319-21.

Treatment of postoperative atelectasis with dornase alpha (Pulmozyme®) after congenital heart surgery

Year 2015, Volume: 2 Issue: 4, 275 - 77, 27.04.2015

Mustafa Zor Abdullah Ozer , Huseyin Demirtas Yigit Kilic Baris Mardin

Abstract

References

  • Pinto Jr VC, Daher CV, Sallum FS, Janete MB, Croti UA. Situação das cirurgias cardíacas congênitas no Brasil. Rev Bras Cir Cardiovascular. 2004; 19(2): 3-4
  • Felcar JM, Guitti JCS, Marson AC, Cardoso JR. Fisioterapiapré-operatória na prevenção das complicações pulmonares emcirurgia cardíaca pediátrica. Rev Bras Cir Cardiovasc. 2008; 23(3):383-8.
  • Andrejaitiene J, Sirvinskas E, Bolys R. The influence of cardiopulmonary bypass on respiratory dysfunction in early postoperative period. Medicina (Kaunas). 2004; 40(Suppl1):7-12.
  • Kavanagh BP. Perioperative atelectasis. Minerva Anestesiol. 2008; 74(6):285-7.
  • Undern-Sternberg BS, Petak F, Saudan S, Pellegrini M, Erb TO, Habre W. Effect of cardiopulmonary bypass and aortic clamping on functional residual capacity and ventilation distribution in children. J Thorac Cardiovasc Surg. 2007; 134(5): 1193-8.
  • Nina RVAH, Gama MEA, Santos AM, Nina VJS, Figueiredo NETO JA, Mendes VGG, et al. O escore de risco ajustado para cirurgia em cardiopatias congênitas (RACHS-1) pode ser aplicado em nosso meio? Rev Bras Cir Cardiovasc. 2007; 22(4): 425-31.
  • Healy, Fiona; D. Hanna, Brian; Zinman, Raezelle Current Respiratory Medicine Reviews, Volume 7, Number 2, April 2011 , pp. 78-86(9 Bentham Science Publishers
  • Lee A. Fleisher. Anesthesia and uncommon disease. Elsevier Health Sciences, 2012; Sixth Ed. pp (6-7)
  • Oh AY, Kim YH, Kim BK, Kim HS, Kim CS Unexpected tracheomalacia in Marfan syndrome during general anesthesia for correction of scoliosis. Anesth Analg 2002; 95: 331-2.
  • Kanter RK, Pollack MM, Wright WW, et al. Treatment of severe tracheobronchomalacia with continuous positive airway pressure (CPAP). Anesthesiology 1982; 57: 54–6.
  • Shah PL, Scott SF, Knight RA, et al. In vivo effect of rhDNase 1 on sputum in patients with cystic fibrosis. Thorax 1996;51(2):119-25.
  • Hassan NO, Chess PR. Rescue use of DNase in critical lung atelectasis and mucus retention in premature neonates. Pediatrics 2001;108:468.
  • Toulemiat B, Conoscenti G, Fine J. Recombinant human Dnase in management of lobar atelectasis due to retained secretions. Thorax 1995;50:1319-21.
There are 13 citations in total.

Details

Primary Language English
Authors

Mustafa Zor This is me

Abdullah Ozer

Huseyin Demirtas This is me

Yigit Kilic This is me

Baris Mardin This is me

Publication Date April 27, 2015
Published in Issue Year 2015 Volume: 2 Issue: 4

Cite

APA Zor, M., Ozer, A., Demirtas, H., … Kilic, Y. (2015). Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery. Medical Science and Discovery, 2(4), 275-77. https://doi.org/10.17546/msd.38808
AMA Zor M, Ozer A, Demirtas H, Kilic Y, Mardin B. Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery. Med Sci Discov. June 2015;2(4):275-77. doi:10.17546/msd.38808
Chicago Zor, Mustafa, Abdullah Ozer, Huseyin Demirtas, Yigit Kilic, and Baris Mardin. “Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery”. Medical Science and Discovery 2, no. 4 (June 2015): 275-77. https://doi.org/10.17546/msd.38808.
EndNote Zor M, Ozer A, Demirtas H, Kilic Y, Mardin B (June 1, 2015) Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery. Medical Science and Discovery 2 4 275–77.
IEEE M. Zor, A. Ozer, H. Demirtas, Y. Kilic, and B. Mardin, “Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery”, Med Sci Discov, vol. 2, no. 4, pp. 275–77, 2015, doi: 10.17546/msd.38808.
ISNAD Zor, Mustafa et al. “Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery”. Medical Science and Discovery 2/4 (June2015), 275-77. https://doi.org/10.17546/msd.38808.
JAMA Zor M, Ozer A, Demirtas H, Kilic Y, Mardin B. Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery. Med Sci Discov. 2015;2:275–77.
MLA Zor, Mustafa et al. “Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery”. Medical Science and Discovery, vol. 2, no. 4, 2015, pp. 275-77, doi:10.17546/msd.38808.
Vancouver Zor M, Ozer A, Demirtas H, Kilic Y, Mardin B. Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery. Med Sci Discov. 2015;2(4):275-77.