Relationship Between Premature ventricular complexes and Neutrophil–Lymphocyte Ratio in asymptomatic healty young men

Abstract

Background: Premature ventricular complexes (PVC) are a relatively common electrocardiographic abnormality presenting in individuals without overt cardiovascular disease. There is no clear mortality benefit from VPB suppression in asymptomatic patients. In addition, It has been showed  that evidence for structural heart disease consistent with non-ischemic scarring possibly due to inflammation in patients with premature ventricular beats . This situation  suggests that the mechanisms by which VPBs can be also  generated with  include  clinical and subclinical inflammation. The neutrophil–lymphocyte ratio (NLR) is an easy, cheap, noninvasive, and universally available laboratory marker used to evaluate clinical and subclinical systemic inflammation.We investigated the NLR in  asymptomatic  healty young men  with  PVC(structural heart disease excluded with cardiac magnetic resonance imaging)   compared with controls.

Methods: The study group consisted of  21  asymptomatic(or atypical complaint)  healty young men  with PVC ( mean age 22.7 ± 2.0 years.

Results:There were no significant differences between the 2 groups with respect to age, gender, body mass index, smoking, as well as glucose, creatinine, total cholesterol, triglyceride, LDL-C, HDL-C,  hemoglobin levels, white blood cell count, and red cell distribution width.  The NLR was significantly higher among the men  with PVC than that of the control group (2.7 ±0.7 vs 1.5 ± 0.4, respectively; P < .001).

Conclusions: We  found that the NLR is significantly elevated in asymptomatic  healty young men  with PVC  compared with control participants. The increased NLR values might indicate subclinical and clinical inflammation in asymptomatic  healty young men  with PVC ,and we must  consider that there

 

Keywords

• Premature ventricular complexes (PVC), neutrophil–lymphocyte ratio (NLR), inflammation

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