Major acute pain complications in Congolese children with sickle cell disease

Abstract

Sickle cell disease is the most frequent genetic blood disorder in the world and pain complications are the most prominent clinical aspects in sickle cell population.

Objectives: Describe the morbidity feature of major acute pain complications in children with sickle cell disease and outcome.

Material and Methods: 166 sickle cell disease children (4.3%) with a mean age of 85.31 months old±60.40 admitted in the pediatric intensive care unit for major acute pain complications were enrolled in the study from January to December 2014. Major acute pain complications were defined as acute sickle cell related pain with an intensity assessed at 3 on the Wong-Baker faces pain rating scale. 

Results:  Over the period study, 118 patients were admitted for diffuse vaso occlusive crisis (70.09%). Localized vaso occlusive crisis occurred in 13.25%, acute chest syndrome in 09.64% and hand foot syndrome in 06. 02%. The most common trigger factors were bacterial infections (65.12%) followed by malaria (34.88%). Mortality of 12.05% was recorded while 27.71% were discharged and 60.24% transferred to other departments. The mortality rate was significantly higher in the range age over 5 years (p=0.004)

Keywords

• Sickle cell disease,Major acute pain; Intensive care department; Congo

Major acute pain complications in Congolese children with sickle cell disease Lydie Ocini Ngolet1*, Moyen Engoba2, Alexis Elira Dokekias1, Kocko Innocent1, George Moyen2

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